Christopher F. Rose

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Rajiv JalanProfessor of Hepatology, UCLVerified email at ucl.ac.uk
Davies N AProfessor, University College LondonVerified email at ucl.ac.uk
Nicolaas E DeutzCenter for Translational Research in Aging and Longevity, Texas A&M UniversityVerified email at tamu.edu
Constantine KarvellasDepartment of Critical Care and Division of Gastroenterology (Liver Unit),University of AlbertaVerified email at ualberta.ca
Ole-Martin FuskevågUiT, the Arctic University of NorwayVerified email at unn.no
Gabriella ten Have Ph.D.Center for Translational Research in Aging and Longevity, Texas A&M UniversityVerified email at tamu.edu
Aldo J. Montano-LozaUniversity of AlbertaVerified email at ualberta.ca
Jasmohan BajajVirginia Commonwealth University and McGuire VA Medical CenterVerified email at vcu.edu
Andres Duarte-RojoUniversity of PittsburghVerified email at upmc.edu
Farzaneh TamnanlooFaculty of Medicine, Université de MontréalVerified email at umontreal.ca
Rajeshwar MookerjeeProfessor of Translational Hepatology, University College LondonVerified email at ucl.ac.uk
Jean-Christophe LerouxETH ZürichVerified email at ethz.ch
Helmut KettenmannProfessor for Neurobiology, MDCVerified email at mdc-berlin.de
Hanne MæhreScientific researcher, NIBIO (Norwegian Institute of Bioeconomy Research)Verified email at nibio.no
Scott NybergProfessor of Surgery, Mayo ClinicVerified email at mayo.edu
Alan S. HazellAssociate professor, Department of medicine, University of MontrealVerified email at umontreal.ca
Vincent ForsterDr. sc. ETH ZürichVerified email at pharma.ethz.ch
Radha K. DhimanProfessor of Hepatology, Postgraduate Institute of Medical Education and Research, ChandigarhVerified email at pgimer.edu.in
Gitte DamAarhus University Hospital. Department of Hepatology and GastroenterologyVerified email at rm.dk
Cristina CudalbuCIBM MRI EPFL Animal Imaging and Technology SectionVerified email at epfl.ch

Christopher F. Rose

Research Professor, Université de Montréal

Verified email at umontreal.ca - Homepage

Hepatic encephalopathy


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Manganese deposition in basal ganglia structures results from both portal-systemic shunting and liver dysfunction C Rose, RF Butterworth, J Zayed, L Normandin, K Todd, A Michalak, ... Gastroenterology 117 (3), 640-644, 1999	342	1999
Hepatic encephalopathy: Novel insights into classification, pathophysiology and therapy CF Rose, P Amodio, JS Bajaj, RK Dhiman, S Montagnese, ... Journal of hepatology 73 (6), 1526-1547, 2020	293	2020
Identifying the direct effects of ammonia on the brain CR Bosoi, CF Rose Metabolic brain disease 24, 95-102, 2009	271	2009
Ammonia toxicity: from head to toe? S Dasarathy, RP Mookerjee, V Rackayova, V Rangroo Thrane, ... Metabolic brain disease 32, 529-538, 2017	223	2017
Astrocyte glutamine synthetase: pivotal in health and disease CF Rose, A Verkhratsky, V Parpura Biochemical Society Transactions 41 (6), 1518-1524, 2013	212	2013
Decreased glutamate transporter (GLT-1) expression in frontal cortex of rats with acute liver failure K Knecht, A Michalak, C Rose, JD Rothstein, RF Butterworth Neuroscience letters 229 (3), 201-203, 1997	209	1997
Neuroactive amino acids and glutamate (NMDA) receptors in frontal cortex of rats with experimental acute liver failure A Michalak, C Rose, J Butterworth, RF Butterworth Hepatology 24 (4), 908-913, 1996	204	1996
L‐Ornithine‐L‐aspartate lowers plasma and cerebrospinal fluid ammonia and prevents brain edema in rats with acute liver failure C Rose, A Michalak, KV Rao, G Quack, G Kircheis, RF Butterworth Hepatology 30 (3), 636-640, 1999	193	1999
Myosteatosis and sarcopenia are associated with hepatic encephalopathy in patients with cirrhosis RA Bhanji, C Moctezuma-Velazquez, A Duarte-Rojo, M Ebadi, S Ghosh, ... Hepatology international 12, 377-386, 2018	191	2018
Ammonia‐lowering strategies for the treatment of hepatic encephalopathy CF Rose Clinical Pharmacology & Therapeutics 92 (3), 321-331, 2012	161	2012
Mild hypothermia delays the onset of coma and prevents brain edema and extracellular brain glutamate accumulation in rats with acute liver failure C Rose, A Michalak, M Pannunzio, N Chatauret, A Rambaldi, ... Hepatology 31 (4), 872-877, 2000	156	2000
Acute insult of ammonia leads to calcium-dependent glutamate release from cultured astrocytes, an effect of pH C Rose, W Kresse, H Kettenmann Journal of biological chemistry 280 (22), 20937-20944, 2005	144	2005
Effects of hypothermia on brain glucose metabolism in acute liver failure: a 1H/13C-nuclear magnetic resonance study N Chatauret, C Zwingmann, C Rose, D Leibfritz, RF Butterworth Gastroenterology 125 (3), 815-824, 2003	123	2003
L-ornithine-L-aspartate in experimental portal-systemic encephalopathy: therapeutic efficacy and mechanism of action C Rose, A Michalak, P Pannunzio, G Therrien, G Quack, G Kircheis, ... Metabolic brain disease 13, 147-157, 1998	120	1998
Oxidative stress: a systemic factor implicated in the pathogenesis of hepatic encephalopathy CR Bosoi, CF Rose Metabolic brain disease 28, 175-178, 2013	113	2013
Role of manganese in the pathogenesis of portal-systemic encephalopathy GP Layrargues, C Rose, L Spahr, J Zayed, L Normandin, RF Butterworth Metabolic brain disease 13, 311-317, 1998	110	1998
L‐ornithine phenylacetate attenuates increased arterial and extracellular brain ammonia and prevents intracranial hypertension in pigs with acute liver failure LM Ytrebø, RG Kristiansen, H Mæhre, OM Fuskevåg, T Kalstad, ... Hepatology 50 (1), 165-174, 2009	106	2009
Effect of portacaval anastomosis on glutamine synthetase protein and gene expression in brain, liver and skeletal muscle P Desjardins, KVR Rao, A Michalak, C Rose, RF Butterworth Metabolic brain disease 14, 273-280, 1999	106	1999
Systemic oxidative stress is implicated in the pathogenesis of brain edema in rats with chronic liver failure. CR Bosoi, X Yang, J Huynh, C Parent-Robitaille, W Jiang, M Tremblay, ... Free radical biology & medicine 52 (7), 1228-1235, 2012	104	2012
Induction of astrocytic cyclooxygenase-2 in epileptic patients with hippocampal sclerosis P Desjardins, A Sauvageau, A Bouthillier, D Navarro, AS Hazell, C Rose, ... Neurochemistry international 42 (4), 299-303, 2003	103	2003

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