Ramona Curpan
Ramona Curpan
Researcher, Institute of Chemistry Timisoara of Romanian Academy
Verified email at acad-icht.tm.edu.ro
Cited by
Cited by
WOMBAT: world of molecular bioactivity
M Olah, M Mracec, L Ostopovici, R Rad, A Bora, N Hadaruga, I Olah, ...
Chemoinformatics in drug discovery 1, 2004
Chemoinformatics in drug discovery
R Mannhold, H Kubinyi, G Folkers
Wiley-VCH, 2005
A crowdsourcing evaluation of the NIH chemical probes
TI Oprea, CG Bologa, S Boyer, RF Curpan, RC Glen, AL Hopkins, ...
Nature chemical biology 5 (7), 441-447, 2009
Lead-like, drug-like or “Pub-like”: how different are they?
TI Oprea, TK Allu, DC Fara, RF Rad, L Ostopovici, CG Bologa
Journal of computer-aided molecular design 21 (1-3), 113-119, 2007
WOMBAT and WOMBAT‐PK: bioactivity databases for lead and drug discovery
M Olah, R Rad, L Ostopovici, A Bora, N Hadaruga, D Hadaruga, ...
Chemical biology: from small molecules to systems biology and drug design 1 …, 2007
The selective estrogen receptor modulator bazedoxifene inhibits hormone-independent breast cancer cell growth and down-regulates estrogen receptor α and cyclin D1
JS Lewis-Wambi, H Kim, R Curpan, R Grigg, MA Sarker, VC Jordan
Molecular pharmacology 80 (4), 610-620, 2011
Molecular mechanism of action of bisphenol and bisphenol A mediated by oestrogen receptor alpha in growth and apoptosis of breast cancer cells
S Sengupta, I Obiorah, PY Maximov, R Curpan, VC Jordan
British journal of pharmacology 169 (1), 167-178, 2013
ChemProt: a disease chemical biology database
O Taboureau, SK Nielsen, K Audouze, N Weinhold, D Edsgärd, FS Roque, ...
Nucleic acids research 39 (suppl_1), D367-D372, 2010
Structure− function relationships of estrogenic triphenylethylenes related to endoxifen and 4-hydroxytamoxifen
PY Maximov, CB Myers, RF Curpan, JS Lewis-Wambi, VC Jordan
Journal of medicinal chemistry 53 (8), 3273-3283, 2010
Chemical biology
SL Schreiber, TM Kapoor, G Wess, GN Wess
Wiley-VCH, 2007
Highly efficient synthesis and characterization of the GPR30-selective agonist G-1 and related tetrahydroquinoline analogs
R Burai, C Ramesh, M Shorty, R Curpan, C Bologa, LA Sklar, T Oprea, ...
Organic & biomolecular chemistry 8 (9), 2252-2259, 2010
Detection of intracellular granularity induction in prostate cancer cell lines by small molecules using the HyperCyt® high-throughput flow cytometry system
MK Haynes, JJ Strouse, A Waller, A Leitao, RF Curpan, C Bologa, ...
Journal of biomolecular screening 14 (6), 596-609, 2009
Estrogen receptor mutations found in breast cancer metastases integrated with the molecular pharmacology of selective ER modulators
VC Jordan, R Curpan, PY Maximov
JNCI: Journal of the National Cancer Institute 107 (6), 2015
The molecular, cellular and clinical consequences of targeting the estrogen receptor following estrogen deprivation therapy
P Fan, PY Maximov, RF Curpan, B Abderrahman, VC Jordan
Molecular and cellular endocrinology 418, 245-263, 2015
High-throughput screen for the chemical inhibitors of antiapoptotic bcl-2 family proteins by multiplex flow cytometry
RF Curpan, PC Simons, D Zhai, SM Young, MB Carter, CG Bologa, ...
Assay and drug development technologies 9 (5), 465-474, 2011
Defining the conformation of the estrogen receptor complex that controls estrogen-induced apoptosis in breast cancer
I Obiorah, S Sengupta, R Curpan, VC Jordan
Molecular pharmacology 85 (5), 789-799, 2014
Structural determinants of the alpha2 adrenoceptor subtype selectivity
L Ostopovici-Halip, R Curpăn, M Mracec, CG Bologa
Journal of Molecular Graphics and Modelling 29 (8), 1030-1038, 2011
The conformation of the estrogen receptor directs estrogen-induced apoptosis in breast cancer: a hypothesis
P Maximov, S Sengupta, JS Lewis-Wambi, HR Kim, RF Curpan, ...
Hormone molecular biology and clinical investigation 5 (1), 27-34, 2011
Influence of the length and positioning of the antiestrogenic side chain of endoxifen and 4-hydroxytamoxifen on gene activation and growth of estrogen receptor positive cancer …
PY Maximov, DJ Fernandes, RE McDaniel, CB Myers, RF Curpan, ...
Journal of medicinal chemistry 57 (11), 4569-4583, 2014
Exploring the biological promiscuity of high-throughput screening hits through DFT calculations
R Curpan, S Avram, R Vianello, C Bologa
Bioorganic and Medicinal Chemistry 22 (8), 2461-2468, 2014
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