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Giovanni Solinas
Giovanni Solinas
University of Gothenburg, Department of Molecular and Clinical Medicine
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The E3 ubiquitin ligase itch couples JNK activation to TNFα-induced cell death by inducing c-FLIPL turnover
L Chang, H Kamata, G Solinas, JL Luo, S Maeda, K Venuprasad, YC Liu, ...
Cell 124 (3), 601-613, 2006
8652006
JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity
G Solinas, C Vilcu, JG Neels, GK Bandyopadhyay, JL Luo, W Naugler, ...
Cell metabolism 6 (5), 386-397, 2007
6442007
Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance
G Tuncman, J Hirosumi, G Solinas, L Chang, M Karin, GS Hotamisligil
Proceedings of the National Academy of Sciences 103 (28), 10741-10746, 2006
4502006
JNK1 and IKKβ: molecular links between obesity and metabolic dysfunction
G Solinas, M Karin
The FASEB Journal 24 (8), 2596-2611, 2010
4362010
JNK at the crossroad of obesity, insulin resistance, and cell stress response
G Solinas, B Becattini
Molecular metabolism 6 (2), 174-184, 2017
3932017
Saturated fatty acids inhibit induction of insulin gene transcription by JNK-mediated phosphorylation of insulin-receptor substrates
G Solinas, W Naugler, F Galimi, MS Lee, M Karin
Proceedings of the National Academy of Sciences 103 (44), 16454-16459, 2006
3632006
Body composition phenotypes in pathways to obesity and the metabolic syndrome
AG Dulloo, J Jacquet, G Solinas, JP Montani, Y Schutz
International journal of obesity 34 (2), S4-S17, 2010
3182010
Saturated fatty acids induce c-Src clustering within membrane subdomains, leading to JNK activation
RG Holzer, EJ Park, N Li, H Tran, M Chen, C Choi, G Solinas, M Karin
Cell 147 (1), 173-184, 2011
3062011
Identification of a new JNK inhibitor targeting the JNK-JIP interaction site
JL Stebbins, SK De, T Machleidt, B Becattini, J Vazquez, C Kuntzen, ...
Proceedings of the National Academy of Sciences 105 (43), 16809-16813, 2008
2232008
De novo lipogenesis in metabolic homeostasis: More friend than foe?
G Solinas, J Borén, AG Dulloo
Molecular metabolism 4 (5), 367-377, 2015
2132015
The direct effect of leptin on skeletal muscle thermogenesis is mediated by substrate cycling between de novo lipogenesis and lipid oxidation
G Solinas, S Summermatter, D Mainieri, M Gubler, L Pirola, MP Wymann, ...
FEBS letters 577 (3), 539-544, 2004
1272004
Leptin directly stimulates thermogenesis in skeletal muscle
AG Dulloo, MJ Stock, G Solinas, O Boss, JP Montani, J Seydoux
FEBS letters 515 (1-3), 109-113, 2002
1072002
Substrate cycling between de novo lipogenesis and lipid oxidation: a thermogenic mechanism against skeletal muscle lipotoxicity and glucolipotoxicity
AG Dulloo, M Gubler, JP Montani, J Seydoux, G Solinas
International Journal of Obesity 28 (4), S29-S37, 2004
1042004
Obesity promotes the expansion of metastasis-initiating cells in breast cancer
M Bousquenaud, F Fico, G Solinas, C Rüegg, A Santamaria-Martínez
Breast Cancer Research 20, 1-11, 2018
952018
PER2 promotes glucose storage to liver glycogen during feeding and acute fasting by inducing Gys2 PTG and GL expression
F Zani, L Breasson, B Becattini, A Vukolic, JP Montani, U Albrecht, ...
Molecular metabolism 2 (3), 292-305, 2013
882013
Hyperinsulinemia and insulin resistance in the obese may develop as part of a homeostatic response to elevated free fatty acids: A mechanistic case-control and a population …
E Fryk, J Olausson, K Mossberg, L Strindberg, M Schmelz, H Brogren, ...
EBioMedicine, 2021
802021
Insulin-driven PI3K-AKT signaling in the hepatocyte is mediated by redundant PI3Kα and PI3Kβ activities and is promoted by RAS
A Molinaro, B Becattini, A Mazzoli, A Bleve, L Radici, I Maxvall, ...
Cell metabolism 29 (6), 1400-1409. e5, 2019
802019
A Role for Adipose Tissue De Novo Lipogenesis in Glucose Homeostasis During Catch-up Growth A Randle Cycle Favoring Fat Storage
H Marcelino, C Veyrat-Durebex, S Summermatter, D Sarafian, ...
Diabetes, 2012
712012
PI3Kγ within a nonhematopoietic cell type negatively regulates diet-induced thermogenesis and promotes obesity and insulin resistance
B Becattini, R Marone, F Zani, D Arsenijevic, J Seydoux, JP Montani, ...
Proceedings of the National Academy of Sciences 108 (42), E854-E863, 2011
652011
Thrifty metabolism that favors fat storage after caloric restriction: a role for skeletal muscle phosphatidylinositol‐3‐kinase activity and AMP‐activated protein kinase
S Summermatter, D Mainieri, AP Russell, J Seydoux, JP Montani, ...
The FASEB Journal 22 (3), 774-785, 2008
632008
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