Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin … A Kuhn, DR Goldstein, A Hodges, AD Strand, T Sengstag, C Kooperberg, ... Human molecular genetics 16 (15), 1845-1861, 2007 | 379 | 2007 |
Length of uninterrupted CAG, independent of polyglutamine size, results in increased somatic instability, hastening onset of Huntington disease GEB Wright, JA Collins, C Kay, C McDonald, E Dolzhenko, Q Xia, ... The American Journal of Human Genetics 104 (6), 1116-1126, 2019 | 157 | 2019 |
A SNP in the HTT promoter alters NF-κB binding and is a bidirectional genetic modifier of Huntington disease K Bečanović, A Nørremølle, SJ Neal, C Kay, JA Collins, D Arenillas, T Lilja, ... Nature neuroscience 18 (6), 807-816, 2015 | 134 | 2015 |
Transcriptional changes in Huntington disease identified using genome-wide expression profiling and cross-platform analysis K Becanovic, MA Pouladi, RS Lim, A Kuhn, P Pavlidis, R Luthi-Carter, ... Human molecular genetics 19 (8), 1438-1452, 2010 | 126 | 2010 |
IL-22RA2 associates with multiple sclerosis and macrophage effector mechanisms in experimental neuroinflammation AD Beyeen, MZ Adzemovic, J Öckinger, P Stridh, K Becanovic, ... The Journal of Immunology 185 (11), 6883-6890, 2010 | 90 | 2010 |
An advanced intercross line resolves Eae18 into two narrow quantitative trait loci syntenic to multiple sclerosis candidate loci M Jagodic, K Becanovic, JR Sheng, X Wu, L Bäckdahl, JC Lorentzen, ... The Journal of Immunology 173 (2), 1366-1373, 2004 | 66 | 2004 |
Forkhead box protein p1 is a transcriptional repressor of immune signaling in the CNS: implications for transcriptional dysregulation in Huntington disease B Tang, K Becanovic, PA Desplats, B Spencer, AM Hill, C Connolly, ... Human molecular genetics 21 (14), 3097-3111, 2012 | 65 | 2012 |
Expression analysis of novel striatal-enriched genes in Huntington disease G Mazarei, SJ Neal, K Becanovic, R Luthi-Carter, EM Simpson, BR Leavitt Human molecular genetics 19 (4), 609-622, 2010 | 63 | 2010 |
Advanced intercross line mapping of Eae5 reveals Ncf-1 and CLDN4 as candidate genes for experimental autoimmune encephalomyelitis K Becanovic, M Jagodic, JR Sheng, I Dahlman, F Aboul-Enein, ... The Journal of Immunology 176 (10), 6055-6064, 2006 | 63 | 2006 |
p53 increases caspase-6 expression and activation in muscle tissue expressing mutant huntingtin DE Ehrnhoefer, NH Skotte, S Ladha, YTN Nguyen, X Qiu, Y Deng, ... Human molecular genetics 23 (3), 717-729, 2014 | 58 | 2014 |
New loci regulating rat myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis K Becanovic, E Wallstrom, B Kornek, A Glaser, KW Broman, I Dahlman, ... The Journal of Immunology 170 (2), 1062-1069, 2003 | 49 | 2003 |
Fine-mapping resolves Eae23 into two QTLs and implicates ZEB1 as a candidate gene regulating experimental neuroinflammation in rat P Stridh, M Thessen Hedreul, AD Beyeen, MZ Adzemovic, H Laaksonen, ... PLoS One 5 (9), e12716, 2010 | 36 | 2010 |
Resolution of a 16.8-Mb autoimmunity-regulating rat chromosome 4 region into multiple encephalomyelitis quantitative trait loci and evidence for epistasis M Jagodic, M Marta, K Becanovic, JR Sheng, R Nohra, T Olsson, ... The Journal of Immunology 174 (2), 918-924, 2005 | 33 | 2005 |
Multiple loci comprising immune-related genes regulate experimental neuroinflammation M Marta, P Stridh, K Becanovic, A Gillett, J Öckinger, JC Lorentzen, ... Genes & Immunity 11 (1), 21-36, 2010 | 29 | 2010 |
Paradoxical effects of arthritis‐regulating chromosome 4 regions on myelin oligodendrocyte glycoprotein‐induced encephalomyelitis in congenic rats K Becanovic, L Bäckdahl, E Wallström, F Aboul‐Enein, H Lassmann, ... European journal of immunology 33 (7), 1907-1916, 2003 | 25 | 2003 |
Eae19, a New Locus on Rat Chromosome 15 Regulating Experimental Autoimmune Encephalomyelitis JR Sheng, M Jagodic, I Dahlman, K Becanovic, R Nohra, M Marta, ... Genetics 170 (1), 283-289, 2005 | 23 | 2005 |
Definition of arthritis candidate risk genes by combining rat linkage-mapping results with human case-control association data L Bäckdahl, JP Guo, M Jagodic, K Becanovic, B Ding, T Olsson, ... Annals of the rheumatic diseases 68 (12), 1925-1932, 2009 | 15 | 2009 |
Current gene‐mapping strategies in experimental models of multiple sclerosis K Becanovic, M Jagodic, E Wallström, T Olsson Scandinavian Journal of immunology 60 (1‐2), 39-51, 2004 | 12 | 2004 |
Age-related mitochondrial alterations in brain and skeletal muscle of the YAC128 model of Huntington disease K Bečanović, M Asghar, I Gadawska, S Sachdeva, D Walker, ... npj Aging and Mechanisms of Disease 7 (1), 26, 2021 | 10 | 2021 |
Identification of Rat Quantitative Trait Loci that Regulate LPS‐Induced Pro‐Inflammatory Cytokine Responses HW XU, E WallstroÈm, K Becanovic, I Dahlman, JC Lorentzen Scandinavian journal of immunology 56 (3), 248-253, 2002 | 9 | 2002 |