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Harry P. De Koning
Harry P. De Koning
Professor of Parasite Biochemistry and Pharmacology, University of Glasgow
Bestätigte E-Mail-Adresse bei glasgow.ac.uk - Startseite
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Zitiert von
Zitiert von
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The animal trypanosomiases and their chemotherapy: a review
F Giordani, LJ Morrison, TG Rowan, HP De Koning, MP Barrett
Parasitology 143 (14), 1862-1889, 2016
4232016
Drugs and drug resistance in African trypanosomiasis
V Delespaux, HP de Koning
Drug resistance updates 10 (1-2), 30-50, 2007
3612007
Pentamidine uptake and resistance in pathogenic protozoa: past, present and future
PG Bray, MP Barrett, SA Ward, HP de Koning
Trends in parasitology 19 (5), 232-239, 2003
3252003
Drug resistance in African trypanosomiasis: the melarsoprol and pentamidine story
N Baker, HP de Koning, P Mäser, D Horn
Trends in parasitology 29 (3), 110-118, 2013
3072013
Mechanisms of Arsenical and Diamidine Uptake and Resistance in Trypanosoma brucei
E Matovu, ML Stewart, F Geiser, R Brun, P Mäser, LJM Wallace, ...
Eukaryotic Cell 2 (5), 1003-1008, 2003
2462003
Purine and pyrimidine transport in pathogenic protozoa: from biology to therapy
HP De Koning, DJ Bridges, RJS Burchmore
FEMS microbiology reviews 29 (5), 987-1020, 2005
2262005
Curcuminoid analogs with potent activity against Trypanosoma and Leishmania species
C Changtam, HP de Koning, H Ibrahim, MS Sajid, MK Gould, ...
European journal of medicinal chemistry 45 (3), 941-956, 2010
2232010
Nucleobase transporters
H de Koning, G Diallinas
Molecular membrane biology 17 (2), 75-94, 2000
2032000
Uptake of pentamidine in Trypanosoma brucei bruceiis mediated by three distinct transporters: implications for cross-resistance with arsenicals
HP De Koning
Molecular pharmacology 59 (3), 586-592, 2001
1902001
Aquaglyceroporin 2 controls susceptibility to melarsoprol and pentamidine in African trypanosomes
N Baker, L Glover, JC Munday, D Aguinaga Andrés, MP Barrett, ...
Proceedings of the National Academy of Sciences 109 (27), 10996-11001, 2012
1762012
Evolutionary genomics of epidemic visceral leishmaniasis in the Indian subcontinent
H Imamura, T Downing, F Van den Broeck, MJ Sanders, S Rijal, S Sundar, ...
Elife 5, e12613, 2016
1622016
Adenosine transporters in bloodstream forms of Trypanosoma brucei brucei: substrate recognition motifs and affinity for trypanocidal drugs
HP de Koning, SM Jarvis
Molecular pharmacology 56 (6), 1162-1170, 1999
1621999
Loss of the high-affinity pentamidine transporter is responsible for high levels of cross-resistance between arsenical and diamidine drugs in African trypanosomes
DJ Bridges, MK Gould, B Nerima, P Mäser, RJS Burchmore, ...
Molecular pharmacology 71 (4), 1098-1108, 2007
1522007
Transporters in African trypanosomes: role in drug action and resistance
HP de Koning
International journal for parasitology 31 (5-6), 512-522, 2001
1522001
Diamidines for human African trypanosomiasis
M Paine, M Wang, WD Wilson, HP De Koning, CA Olson, G Pohlig, ...
Current opinion in investigational drugs 11 (8), 876-883, 2010
149*2010
Trypanosoma brucei aquaglyceroporin 2 is a high-affinity transporter for pentamidine and melaminophenyl arsenic drugs and the main genetic determinant of …
JC Munday, AA Eze, N Baker, L Glover, C Clucas, D Aguinaga Andrés, ...
Journal of Antimicrobial Chemotherapy 69 (3), 651-663, 2014
1372014
The trypanocide diminazene aceturate is accumulated predominantly through the TbAT1 purine transporter: additional insights on diamidine resistance in African trypanosomes
HP de Koning, LF Anderson, M Stewart, RJS Burchmore, LJM Wallace, ...
Antimicrobial Agents and Chemotherapy 48 (5), 1515-1519, 2004
1302004
Diamidine Compounds: Selective Uptake and Targeting inPlasmodium falciparum
AMW Stead, PG Bray, IG Edwards, HP DeKoning, BC Elford, PA Stocks, ...
Molecular pharmacology 59 (5), 1298-1306, 2001
1222001
Different substrate recognition motifs of human and trypanosome nucleobase transporters: selective uptake of purine antimetabolites
LJM Wallace, D Candlish, HP De Koning
Journal of Biological Chemistry 277 (29), 26149-26156, 2002
1112002
Pharmacological Validation of Trypanosoma brucei Phosphodiesterases as Novel Drug Targets
HP de Koning, MK Gould, GJ Sterk, H Tenor, S Kunz, E Luginbuehl, ...
Journal of infectious diseases 206 (2), 229-237, 2012
1052012
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