Structural insights into HDAC6 tubulin deacetylation and its selective inhibition Y Miyake, JJ Keusch, L Wang, M Saito, D Hess, X Wang, BJ Melancon, ... Nature chemical biology 12 (9), 748-754, 2016 | 289 | 2016 |
Memo is a copper-dependent redox protein with an essential role in migration and metastasis G MacDonald, I Nalvarte, T Smirnova, M Vecchi, N Aceto, A Doelemeyer, ... Science signaling 7 (329), ra56-ra56, 2014 | 164 | 2014 |
Expression cloning of a new member of the ABO blood group glycosyltransferases, iGb3 synthase, that directs the synthesis of isoglobo-glycosphingolipids JJ Keusch, SM Manzella, KA Nyame, RD Cummings, JU Baenziger Journal of Biological Chemistry 275 (33), 25308-25314, 2000 | 126 | 2000 |
Cloning of Gb3 synthase, the key enzyme in globo-series glycosphingolipid synthesis, predicts a family of α1, 4-glycosyltransferases conserved in plants, insects, and mammals JJ Keusch, SM Manzella, KA Nyame, RD Cummings, JU Baenziger Journal of Biological Chemistry 275 (33), 25315-25321, 2000 | 123 | 2000 |
Identification and characterization of aβ1, 3-glucosyltransferase that synthesizes the Glc-β1, 3-Fuc disaccharide on thrombospondin type 1 repeats K Kozma, JJ Keusch, B Hegemann, KB Luther, D Klein, D Hess, ... Journal of biological chemistry 281 (48), 36742-36751, 2006 | 96 | 2006 |
Structure of human POFUT2: insights into thrombospondin type 1 repeat fold and O‐fucosylation CI Chen, JJ Keusch, D Klein, D Hess, J Hofsteenge, H Gut The EMBO journal 31 (14), 3183-3197, 2012 | 85 | 2012 |
Peters plus syndrome is a new congenital disorder of glycosylation and involves defective O-glycosylation of thrombospondin type 1 repeats D Hess, JJ Keusch, SAL Oberstein, RCM Hennekam, J Hofsteenge Journal of biological chemistry 283 (12), 7354-7360, 2008 | 81 | 2008 |
The TRIM-NHL Protein LIN-41 Controls the Onset of Developmental Plasticity in Caenorhabditis elegans C Tocchini, JJ Keusch, SB Miller, S Finger, H Gut, MB Stadler, R Ciosk PLoS genetics 10 (8), e1004533, 2014 | 79 | 2014 |
Structural basis of Mec1-Ddc2-RPA assembly and activation on single-stranded DNA at sites of damage I Deshpande, A Seeber, K Shimada, JJ Keusch, H Gut, SM Gasser Molecular cell 68 (2), 431-445. e5, 2017 | 71 | 2017 |
Acyl coenzyme A thioesterase Them5/Acot15 is involved in cardiolipin remodeling and fatty liver development E Zhuravleva, H Gut, D Hynx, D Marcellin, CKE Bleck, C Genoud, P Cron, ... Molecular and cellular biology 32 (14), 2685-2697, 2012 | 65 | 2012 |
Influenza virus uses transportin 1 for vRNP debundling during cell entry Y Miyake, JJ Keusch, L Decamps, H Ho-Xuan, S Iketani, H Gut, U Kutay, ... Nature microbiology 4 (4), 578-586, 2019 | 60 | 2019 |
The effect on IgG glycosylation of altering beta 1, 4- galactosyltransferase-1 activity in B cells J Keusch, PM Lydyard, PJ Delves Glycobiology 8 (12), 1215-1220, 1998 | 43 | 1998 |
Dimerization of Sir3 via its C‐terminal winged helix domain is essential for yeast heterochromatin formation M Oppikofer, S Kueng, JJ Keusch, M Hassler, AG Ladurner, H Gut, ... The EMBO Journal 32 (3), 437-449, 2013 | 40 | 2013 |
Evolutionary plasticity of the NHL domain underlies distinct solutions to RNA recognition P Kumari, F Aeschimann, D Gaidatzis, JJ Keusch, P Ghosh, A Neagu, ... Nature communications 9 (1), 1549, 2018 | 39 | 2018 |
B lymphocyte galactosyltransferase protein levels in normal individuals and in patients with rheumatoid arthritis J Keusch, PM Lydyard, EG Berger, PJ Delves Glycoconjugate journal 15, 1093-1097, 1998 | 37 | 1998 |
β1, 4-Galactosyltransferase activity in B cells detected using a simple ELISA-based assay J Keusch, PM Lydyard, DA Isenberg, PJ Delves Glycobiology 5 (4), 365-370, 1995 | 37 | 1995 |
Analysis of different glycosylation states in IgG subclasses J Keusch, Y Levy, Y Shoenfeld, P Youinou Clinica chimica acta 252 (2), 147-158, 1996 | 36 | 1996 |
The Sir4 H‐BRCT domain interacts with phospho‐proteins to sequester and repress yeast heterochromatin I Deshpande, JJ Keusch, K Challa, V Iesmantavicius, SM Gasser, H Gut The EMBO journal 38 (20), e101744, 2019 | 9 | 2019 |
The effect on immunoglobulin glycosylation of altering in vivo production of immunoglobulin G P Jeddi, J Keusch, PM Lydyard, KB Bodman‐Smith, MS Chesnutt, ... Immunology 98 (3), 475-480, 1999 | 7 | 1999 |
Tiopronine-induced reduction of rheumatoid factor functional affinity and asialylated IgG in patients with rheumatoid arthritis. P Youinou, J Keusch, R Casburn-Budd, L Paolozzi, A Lamour, P Le Goff, ... Clinical and experimental rheumatology 10 (4), 333-338, 1992 | 7 | 1992 |