| Brd4 binds to active enhancers to control cell identity gene induction in adipogenesis and myogenesis JE Lee, YK Park, S Park, Y Jang, N Waring, A Dey, K Ozato, B Lai, ... Nature communications 8 (1), 2217, 2017 | 189 | 2017 |
| HIF-1-dependent induction of Jumonji domain-containing protein (JMJD) 3 under hypoxic conditions HY Lee, K Choi, H Oh, YK Park, H Park Molecules and cells 37 (1), 43-50, 2014 | 95 | 2014 |
| Glucocorticoid receptor accelerates, but is dispensable for, adipogenesis YK Park, K Ge Molecular and cellular biology 37 (2), e00260-16, 2017 | 89 | 2017 |
| Clioquinol, a Cu (II)/Zn (II) chelator, inhibits both ubiquitination and asparagine hydroxylation of hypoxia-inducible factor-1α, leading to expression of vascular endothelial … SM Choi, KO Choi, YK Park, H Cho, EG Yang, H Park Journal of biological chemistry 281 (45), 34056-34063, 2006 | 74 | 2006 |
| Depletion of Nsd2-mediated histone H3K36 methylation impairs adipose tissue development and function L Zhuang, Y Jang, YK Park, JE Lee, S Jain, E Froimchuk, A Broun, C Liu, ... Nature Communications 9 (1), 1796, 2018 | 67 | 2018 |
| Nitric oxide donor,(±)-S-nitroso-N-acetylpenicillamine, stabilizes transactive hypoxia-inducible factor-1α by inhibiting von Hippel-Lindau recruitment and asparagine hydroxylation YK Park, DR Ahn, M Oh, T Lee, EG Yang, M Son, H Park Molecular pharmacology 74 (1), 236-245, 2008 | 61 | 2008 |
| Distinct Roles of Transcription Factors KLF4, Krox20, and Peroxisome Proliferator-Activated Receptor γ in Adipogenesis YK Park, L Wang, A Giampietro, B Lai, JE Lee, K Ge Molecular and cellular biology 37 (2), e00554-16, 2017 | 60 | 2017 |
| H3. 3K4M destabilizes enhancer H3K4 methyltransferases MLL3/MLL4 and impairs adipose tissue development Y Jang, A Broun, C Wang, YK Park, L Zhuang, JE Lee, E Froimchuk, C Liu, ... Nucleic Acids Research 47 (2), 607-620, 2019 | 59 | 2019 |
| Estrogen receptor beta inhibits transcriptional activity of hypoxia inducible factor-1 through the downregulation of arylhydrocarbon receptor nuclear translocator W Lim, Y Park, J Cho, C Park, J Park, YK Park, H Park, YJ Lee Breast Cancer Research 13, 1-12, 2011 | 50 | 2011 |
| Interplay of BAF and MLL4 promotes cell type-specific enhancer activation YK Park, JE Lee, Z Yan, K McKernan, T O’Haren, W Wang, W Peng, K Ge Nature communications 12 (1), 1630, 2021 | 42 | 2021 |
| Differentiated embryo chondrocyte 1 (DEC1) represses PPARγ2 gene through interacting with CCAAT/enhancer binding protein β (C/EBPβ) YK Park, H Park Molecules and cells 33, 575-581, 2012 | 41 | 2012 |
| Hypoxia-inducible factor-2α-dependent hypoxic induction of Wnt10b expression in adipogenic cells YK Park, B Park, S Lee, K Choi, Y Moon, H Park Journal of Biological Chemistry 288 (36), 26311-26322, 2013 | 37 | 2013 |
| Prevention of CCAAT/enhancer-binding protein β DNA binding by hypoxia during adipogenesis YK Park, H Park Journal of biological chemistry 285 (5), 3289-3299, 2010 | 31 | 2010 |
| MED1 is a lipogenesis coactivator required for postnatal adipose expansion Y Jang, YK Park, JE Lee, D Wan, N Tran, O Gavrilova, K Ge Genes & Development 35 (9-10), 713-728, 2021 | 15 | 2021 |
| MLL3/MLL4 methyltransferase activities control early embryonic development and embryonic stem cell differentiation in a lineage-selective manner G Xie, JE Lee, AD Senft, YK Park, Y Jang, S Chakraborty, JJ Thompson, ... Nature Genetics 55 (4), 693-705, 2023 | 14 | 2023 |
| BET inhibitors target the SCLC-N subtype of small-cell lung cancer by blocking NEUROD1 transactivation H Chen, L Gesumaria, YK Park, TG Oliver, DS Singer, K Ge, DS Schrump Molecular Cancer Research 21 (2), 91-101, 2023 | 14 | 2023 |
| MLL3/MLL4 methyltransferase activities regulate embryonic stem cell differentiation independent of enhancer H3K4me1 G Xie, JE Lee, K McKernan, YK Park, Y Jang, C Liu, W Peng, K Ge bioRxiv, 2020.09. 14.296558, 2020 | 7 | 2020 |
| Interplay of BAF and MLL4 promotes cell type-specific enhancer activation. Nat Commun 12, 1630 YK Park, JE Lee, Z Yan, K McKernan, T O’Haren, W Wang, W Peng, K Ge | 5 | 2021 |
| a Cu (II)/Zn (II) chelator inhibits both ubiquitination and asparagine hydroxylation of HIF-1alpha, leading to expression of VEGF and EPO in normoxic cells SM Choi, KO Choi, YK Park, H Cho, EG Yang, HC Park J Biol Chem 281, 34056-34063, 2006 | 2 | 2006 |
| H3. 3K4M destabilizes enhancer epigenomic writers MLL3/4 and impairs adipose tissue development Y Jang, C Wang, A Broun, YK Park, L Zhuang, JE Lee, E Froimchuk, C Liu, ... bioRxiv, 301986, 2018 | | 2018 |
Kai Ge, PhDSenior Investigator and Section Chief, NIDDK, NIHAdresse e-mail validée de nih.gov
