Giulia Palermo
TitoloCitata daAnno
Catalytic metal ions and enzymatic processing of DNA and RNA
G Palermo, A Cavalli, ML Klein, M Alfonso-Prieto, M Dal Peraro, ...
Accounts of chemical research 48 (2), 220-228, 2015
762015
Fighting cancer with transition metal complexes: from naked DNA to protein and chromatin targeting strategies
G Palermo, A Magistrato, T Riedel, T Von Erlach, CA Davey, PJ Dyson, ...
ChemMedChem 11 (12), 1199-1210, 2016
582016
CRISPR-Cas9 conformational activation as elucidated from enhanced molecular simulations
G Palermo, Y Miao, RC Walker, M Jinek, JA McCammon
Proceedings of the National Academy of Sciences 114 (28), 7260-7265, 2017
532017
Effect of Electronegative Substituents and Angular Dependence on the Heteronuclear Spin−Spin Coupling Constant 3JC−H: An Empirical Prediction Equation …
G Palermo, R Riccio, G Bifulco
The Journal of organic chemistry 75 (6), 1982-1991, 2010
412010
Valence and conduction band tuning in halide perovskites for solar cell applications
S Meloni, G Palermo, N Ashari-Astani, M Grätzel, U Rothlisberger
Journal of Materials Chemistry A 4 (41), 15997-16002, 2016
392016
Molecular simulations highlight the role of metals in catalysis and inhibition of type II topoisomerase
G Palermo, M Stenta, A Cavalli, M Dal Peraro, M De Vivo
Journal of chemical theory and computation 9 (2), 857-862, 2013
392013
Striking plasticity of CRISPR-Cas9 and key role of non-target DNA, as revealed by molecular simulations
G Palermo, Y Miao, RC Walker, M Jinek, JA McCammon
ACS central science 2 (10), 756-763, 2016
362016
Covalent inhibitors of fatty acid amide hydrolase: a rationale for the activity of piperidine and piperazine aryl ureas
G Palermo, D Branduardi, M Masetti, A Lodola, M Mor, D Piomelli, ...
Journal of medicinal chemistry 54 (19), 6612-6623, 2011
362011
Protospacer Adjacent Motif-Induced Allostery Activates CRISPR-Cas9
G Palermo, CG Ricci, A Fernando, R Basak, M Jinek, I Rivalta, ...
Journal of the American Chemical Society, 2017
312017
Who activates the nucleophile in ribozyme catalysis? An answer from the splicing mechanism of group II introns
L Casalino, G Palermo, U Rothlisberger, A Magistrato
Journal of the American Chemical Society 138 (33), 10374-10377, 2016
312016
Computational insights into function and inhibition of fatty acid amide hydrolase
G Palermo, U Rothlisberger, A Cavalli, M De Vivo
European journal of medicinal chemistry 91, 15-26, 2015
302015
An optimized polyamine moiety boosts the potency of human type II topoisomerase poisons as quantified by comparative analysis centered on the clinical candidate F14512
G Palermo, E Minniti, ML Greco, L Riccardi, E Simoni, M Convertino, ...
Chemical Communications 51 (76), 14310-14313, 2015
292015
Allosteric cross-talk in chromatin can mediate drug-drug synergy
Z Adhireksan*, G Palermo*, T Riedel*, Z Ma, R Muhammad, ...
Nature Communications 8, 2017
272017
Keys to lipid selection in fatty acid amide hydrolase catalysis: structural flexibility, gating residues and multiple binding pockets
G Palermo, I Bauer, P Campomanes, A Cavalli, A Armirotti, S Girotto, ...
PLoS computational biology 11 (6), e1004231, 2015
242015
Development of Site-specific Mg2+-RNA Force Field Parameters: A Dream or Reality? Guidelines from Combined Molecular Dynamics and Quantum Mechanics Simulations
L Casalino, G Palermo, N Abdurakhmonova, U Rothlisberger, ...
Journal of Chemical Theory and Computation 13 (1), 340-352, 2017
232017
Allostery in its many disguises: from theory to applications
SJ Wodak, E Paci, NV Dokholyan, IN Berezovsky, A Horovitz, J Li, ...
Structure, 2019
222019
Anandamide hydrolysis in FAAH reveals a dual strategy for efficient enzyme-assisted amide bond cleavage via nitrogen inversion
G Palermo, P Campomanes, A Cavalli, U Rothlisberger, M De Vivo
The Journal of Physical Chemistry B 119 (3), 789-801, 2014
222014
Wagging the tail: Essential role of substrate flexibility in FAAH catalysis
G Palermo, P Campomanes, M Neri, D Piomelli, A Cavalli, ...
Journal of chemical theory and computation 9 (2), 1202-1213, 2013
212013
Key role of the REC lobe during CRISPR–Cas9 activation by ‘sensing’,‘regulating’, and ‘locking’the catalytic HNH domain
G Palermo, JS Chen, CG Ricci, I Rivalta, M Jinek, VS Batista, JA Doudna, ...
Quarterly reviews of biophysics 51, 2018
192018
The molecular basis for dual fatty acid amide hydrolase (FAAH)/cyclooxygenase (COX) inhibition
G Palermo, AD Favia, M Convertino, M De Vivo
ChemMedChem 11 (12), 1252-1258, 2016
192016
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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