Simon Knott
Simon Knott
Research Investigator, Cold Spring Harbor Laboratory
Verified email at
Cited by
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A model of breast cancer heterogeneity reveals vascular mimicry as a driver of metastasis
E Wagenblast, M Soto, S Gutiérrez-Angel, CA Hartl, AL Gable, AR Maceli, ...
Nature 520 (7547), 358-362, 2015
The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis
JJ Ipsaro, AD Haase, SR Knott, L Joshua-Tor, GJ Hannon
Nature 491 (7423), 279-283, 2012
Asparagine bioavailability governs metastasis in a model of breast cancer
SRV Knott, E Wagenblast, S Khan, SY Kim, M Soto, M Wagner, ...
Nature 554 (7692), 378-381, 2018
Forkhead transcription factors establish origin timing and long-range clustering in S. cerevisiae
SRV Knott, JM Peace, AZ Ostrow, Y Gan, AE Rex, CJ Viggiani, S Tavaré, ...
Cell 148 (1-2), 99-111, 2012
Genome-wide replication profiles indicate an expansive role for Rpd3L in regulating replication initiation timing or efficiency, and reveal genomic loci of Rpd3 function in …
SRV Knott, CJ Viggiani, S Tavaré, OM Aparicio
Genes & development 23 (9), 1077-1090, 2009
Rad53 regulates replication fork restart after DNA damage in Saccharomyces cerevisiae
SJ Szyjka, JG Aparicio, CJ Viggiani, S Knott, W Xu, S Tavaré, OM Aparicio
Genes & development 22 (14), 1906-1920, 2008
The level of origin firing inversely affects the rate of replication fork progression
Y Zhong, T Nellimoottil, JM Peace, SRV Knott, SK Villwock, JM Yee, ...
Journal of Cell Biology 201 (3), 373-383, 2013
A computational algorithm to predict shRNA potency
SRV Knott, AR Maceli, N Erard, K Chang, K Marran, X Zhou, A Gordon, ...
Molecular cell 56 (6), 796-807, 2014
Male-specific Fruitless isoforms have different regulatory roles conferred by distinct zinc finger DNA binding domains
JE Dalton, JM Fear, S Knott, BS Baker, LM McIntyre, MN Arbeitman
BMC genomics 14 (1), 1-15, 2013
Genome-wide network analysis reveals the global properties of IFN-β immediate transcriptional effects in humans
GH Fernald, S Knott, A Pachner, SJ Caillier, K Narayan, JR Oksenberg, ...
The Journal of Immunology 178 (8), 5076-5085, 2007
Complimentary mechanisms of dual checkpoint blockade expand unique T-cell repertoires and activate adaptive anti-tumor immunity in triple-negative breast tumors
EJ Crosby, J Wei, XY Yang, G Lei, T Wang, CX Liu, P Agarwal, AJ Korman, ...
Oncoimmunology 7 (5), e1421891, 2018
Dynamic, mating-induced gene expression changes in female head and brain tissues of Drosophila melanogaster
JE Dalton, TS Kacheria, SRV Knott, MS Lebo, A Nishitani, LE Sanders, ...
BMC genomics 11 (1), 1-13, 2010
Fkh1 and Fkh2 bind multiple chromosomal elements in the S. cerevisiae genome with distinct specificities and cell cycle dynamics
AZ Ostrow, T Nellimoottil, SRV Knott, CA Fox, S Tavare, OM Aparicio
PLoS One 9 (2), e87647, 2014
A CRISPR resource for individual, combinatorial, or multiplexed gene knockout
N Erard, SRV Knott, GJ Hannon
Molecular cell 67 (2), 348-354. e4, 2017
Genome-wide analysis of DNA synthesis by BrdU immunoprecipitation on tiling microarrays (BrdU-IP-chip) in Saccharomyces cerevisiae
CJ Viggiani, SRV Knott, OM Aparicio
Cold Spring Harbor Protocols 2010 (2), pdb. prot5385, 2010
lncRNA requirements for mouse acute myeloid leukemia and normal differentiation
MJ Delas, LR Sabin, E Dolzhenko, SRV Knott, EM Maravilla, BT Jackson, ...
Elife 6, e25607, 2017
Translocation of viable gut microbiota to mesenteric adipose drives formation of creeping fat in humans
CWY Ha, A Martin, GD Sepich-Poore, B Shi, Y Wang, K Gouin, ...
Cell 183 (3), 666-683. e17, 2020
RNF17 blocks promiscuous activity of PIWI proteins in mouse testes
KA Wasik, OH Tam, SR Knott, I Falciatori, M Hammell, VV Vagin, ...
Genes & development 29 (13), 1403-1415, 2015
Lymph node metastases develop through a wider evolutionary bottleneck than distant metastases
JG Reiter, WT Hung, IH Lee, S Nagpal, P Giunta, S Degner, G Liu, ...
Nature genetics 52 (7), 692-700, 2020
To promote and protect: coordinating DNA replication and transcription for genome stability
SRV Knott, CJ Viggiani, OM Aparicio
Epigenetics 4 (6), 362-365, 2009
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