| Beyond Wnt inhibition: new functions of secreted Frizzled-related proteins in development and disease P Bovolenta, P Esteve, JM Ruiz, E Cisneros, J Lopez-Rios J Cell Sci 121 (6), 737-746, 2008 | 777 | 2008 |
| Enhancer redundancy provides phenotypic robustness in mammalian development M Osterwalder, I Barozzi, V Tissières, Y Fukuda-Yuzawa, BJ Mannion, ... Nature 554 (7691), 239, 2018 | 571 | 2018 |
| Recapitulation of endochondral bone formation using human adult mesenchymal stem cells as a paradigm for developmental engineering C Scotti, B Tonnarelli, A Papadimitropoulos, A Scherberich, S Schaeren, ... Proceedings of the National Academy of Sciences 107 (16), 7251-7256, 2010 | 532 | 2010 |
| Vertebrate limb bud development: moving towards integrative analysis of organogenesis R Zeller, J López-Ríos, A Zuniga Nature Reviews Genetics 10 (12), 845-858, 2009 | 501 | 2009 |
| Progressive loss of function in a limb enhancer during snake evolution EZ Kvon, OK Kamneva, US Melo, I Barozzi, M Osterwalder, BJ Mannion, ... Cell 167 (3), 633-642. e11, 2016 | 315 | 2016 |
| Reduction of BMP4 activity by gremlin 1 enables ureteric bud outgrowth and GDNF/WNT11 feedback signalling during kidney branching morphogenesis O Michos, A Gonçalves, J Lopez-Rios, E Tiecke, F Naillat, K Beier, A Galli, ... Development 134 (13), 2397-2405, 2007 | 230 | 2007 |
| Genomic cloning and characterization of the human homeobox gene SIX6 reveals a cluster of SIX genes in chromosome 14 and associates SIX6 hemizygosity with bilateral … ME Gallardo, J Lopez-Rios, I Fernaud-Espinosa, B Granadino, R Sanz, ... Genomics 61 (1), 82-91, 1999 | 189 | 1999 |
| Six3 and Six6 activity is modulated by members of the groucho family J López-Ríos, K Tessmar, F Loosli, J Wittbrodt, P Bovolenta Development 130 (1), 185-195, 2003 | 144 | 2003 |
| Attenuated sensing of SHH by Ptch1 underlies evolution of bovine limbs J Lopez-Rios, A Duchesne, D Speziale, G Andrey, KA Peterson, ... Nature 511 (7507), 46-51, 2014 | 126 | 2014 |
| HAND2 targets define a network of transcriptional regulators that compartmentalize the early limb bud mesenchyme M Osterwalder, D Speziale, M Shoukry, R Mohan, R Ivanek, M Kohler, ... Developmental cell 31 (3), 345-357, 2014 | 117 | 2014 |
| GLI3 constrains digit number by controlling both progenitor proliferation and BMP-dependent exit to chondrogenesis J Lopez-Rios, D Speziale, D Robay, M Scotti, M Osterwalder, ... Developmental cell 22 (4), 837-848, 2012 | 112 | 2012 |
| Six9 (Optx2), a new member of the six gene family of transcription factors, is expressed at early stages of vertebrate ocular and pituitary development J López-Rı́os, ME Gallardo, SR de Córdoba, P Bovolenta Mechanisms of development 83 (1-2), 155-159, 1999 | 94 | 1999 |
| Dual RMCE for efficient re-engineering of mouse mutant alleles M Osterwalder, A Galli, B Rosen, WC Skarnes, R Zeller, J Lopez-Rios Nature methods 7 (11), 893-895, 2010 | 85 | 2010 |
| The Netrin-related domain of Sfrp1 interacts with Wnt ligands and antagonizes their activity in the anterior neural plate J Lopez-Rios, P Esteve, JM Ruiz, P Bovolenta Neural development 3 (1), 19, 2008 | 80 | 2008 |
| Hand2 Is an Essential Regulator for Two Notch-Dependent Functions within the Embryonic Endocardium NJ VanDusen, J Casanovas, JW Vincentz, BA Firulli, M Osterwalder, ... Cell reports 9 (6), 2071-2083, 2014 | 69 | 2014 |
| The many lives of SHH in limb development and evolution J Lopez-Rios Seminars in cell & developmental biology 49, 116-124, 2016 | 67 | 2016 |
| HAND2 Target Gene Regulatory Networks Control Atrioventricular Canal and Cardiac Valve Development F Laurent, A Girdziusaite, J Gamart, I Barozzi, M Osterwalder, JA Akiyama, ... Cell reports 19 (8), 1602-1613, 2017 | 62 | 2017 |
| HAND2 target gene regulatory networks control atrioventricular canal and cardiac valve development F Laurent, A Girdziusaite, J Gamart, I Barozzi, M Osterwalder, JA Akiyama, ... Cell reports 19 (8), 1602-1613, 2017 | 62 | 2017 |
| Genomic Cloning, Structure, Expression Pattern, and Chromosomal Location of the HumanSIX3Gene B Granadino, ME Gallardo, J López-Rı́os, R Sanz, C Ramos, C Ayuso, ... Genomics 55 (1), 100-105, 1999 | 52 | 1999 |
| SFRP1 is required for the proper establishment of the eye field in the medaka fish P Esteve, J Lopez-Rios, P Bovolenta Mechanisms of development 121 (7), 687-701, 2004 | 49 | 2004 |
