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Oliver Wirths
Oliver Wirths
Associate Professor, University Medical Center Göttingen
Verified email at gwdg.de
Title
Cited by
Cited by
Year
Motor deficits, neuron loss, and reduced anxiety coinciding with axonal degeneration and intraneuronal Aβ aggregation in the 5XFAD mouse model of Alzheimer's disease
S Jawhar, A Trawicka, C Jenneckens, TA Bayer, O Wirths
Neurobiology of aging 33 (1), 196. e29-196. e40, 2012
5692012
Massive CA1/2 neuronal loss with intraneuronal and N-terminal truncated Aβ42 accumulation in a novel Alzheimer transgenic model
C Casas, N Sergeant, JM Itier, V Blanchard, O Wirths, N Van Der Kolk, ...
The American journal of pathology 165 (4), 1289-1300, 2004
5342004
A modified β‐amyloid hypothesis: intraneuronal accumulation of the β‐amyloid peptide–the first step of a fatal cascade
O Wirths, G Multhaup, TA Bayer
Journal of neurochemistry 91 (3), 513-520, 2004
5132004
Intraneuronal Aβ accumulation precedes plaque formation in β-amyloid precursor protein and presenilin-1 double-transgenic mice
O Wirths, G Multhaup, C Czech, V Blanchard, S Moussaoui, G Tremp, ...
Neuroscience letters 306 (1-2), 116-120, 2001
4192001
Hippocampal neuron loss exceeds amyloid plaque load in a transgenic mouse model of Alzheimer's disease
C Schmitz, BPF Rutten, A Pielen, S Schäfer, O Wirths, G Tremp, C Czech, ...
The American journal of pathology 164 (4), 1495-1502, 2004
3762004
Time sequence of maturation of dystrophic neurites associated with Aβ deposits in APP/PS1 transgenic mice
V Blanchard, S Moussaoui, C Czech, N Touchet, B Bonici, M Planche, ...
Experimental neurology 184 (1), 247-263, 2003
3502003
Intracellular accumulation of amyloid-Beta-a predictor for synaptic dysfunction and neuron loss in Alzheimer's disease
TA Bayer, O Wirths
Frontiers in aging neuroscience 2, 1359, 2010
2842010
Key factors in Alzheimer's disease: β‐amyloid precursor protein processing, metabolism and intraneuronal transport
TA Bayer, O Wirths, K Majtényi, T Hartmann, G Multhaup, K Beyreuther, ...
Brain Pathology 11 (1), 1-11, 2001
2572001
Pyroglutamate amyloid-β (Aβ): a hatchet man in Alzheimer disease
S Jawhar, O Wirths, TA Bayer
Journal of Biological Chemistry 286 (45), 38825-38832, 2011
2422011
Intraneuronal pyroglutamate-Abeta 3–42 triggers neurodegeneration and lethal neurological deficits in a transgenic mouse model
O Wirths, H Breyhan, H Cynis, S Schilling, HU Demuth, TA Bayer
Acta neuropathologica 118, 487-496, 2009
2082009
N-truncated amyloid β (Aβ) 4-42 forms stable aggregates and induces acute and long-lasting behavioral deficits
Y Bouter, K Dietrich, JL Wittnam, N Rezaei-Ghaleh, T Pillot, ...
Acta neuropathologica 126, 189-205, 2013
1942013
Overexpression of human Dickkopf-1, an antagonist of wingless/WNT signaling, in human hepatoblastomas and Wilms’ tumors
O Wirths, A Waha, S Weggen, P Schirmacher, T Kühne, CG Goodyer, ...
Laboratory investigation 83 (3), 429-434, 2003
1852003
Focusing the amyloid cascade hypothesis on N-truncated Abeta peptides as drug targets against Alzheimer’s disease
TA Bayer, O Wirths
Acta neuropathologica 127, 787-801, 2014
1702014
Intraneuronal APP/Aβ Trafficking and Plaque Formation in β‐Amyloid Precursor Protein and Presenilin‐1 Transgenic Mice
O Wirths, G Multhaup, C Czech, N Feldmann, V Blanchard, G Tremp, ...
Brain Pathology 12 (3), 275-286, 2002
1562002
Transient intraneuronal Aβ rather than extracellular plaque pathology correlates with neuron loss in the frontal cortex of APP/PS1KI mice
DZ Christensen, SL Kraus, A Flohr, MC Cotel, O Wirths, TA Bayer
Acta neuropathologica 116, 647-655, 2008
1522008
Axonopathy in an APP/PS1 transgenic mouse model of Alzheimer’s disease
O Wirths, J Weis, J Szczygielski, G Multhaup, TA Bayer
Acta neuropathologica 111, 312-319, 2006
1522006
Histone deacetylase inhibitor valproic acid inhibits cancer cell proliferation via down-regulation of the alzheimer amyloid precursor protein
V Venkataramani, C Rossner, L Iffland, S Schweyer, IY Tamboli, J Walter, ...
Journal of biological chemistry 285 (14), 10678-10689, 2010
1512010
Inflammatory changes are tightly associated with neurodegeneration in the brain and spinal cord of the APP/PS1KI mouse model of Alzheimer's disease
O Wirths, H Breyhan, A Marcello, MC Cotel, W Brück, TA Bayer
Neurobiology of aging 31 (5), 747-757, 2010
1502010
Age-dependent axonal degeneration in an Alzheimer mouse model
O Wirths, J Weis, R Kayed, TC Saido, TA Bayer
Neurobiology of aging 28 (11), 1689-1699, 2007
1462007
Neuron loss in transgenic mouse models of Alzheimer's disease
O Wirths, TA Bayer
International journal of Alzheimer’s disease 2010, 2010
1342010
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