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Anna Rutkowska
Anna Rutkowska
Heidelberg
Verified email at gsk.com
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Year
Multiplexed proteome dynamics profiling reveals mechanisms controlling protein homeostasis
MM Savitski, N Zinn, M Faelth-Savitski, D Poeckel, S Gade, I Becher, ...
Cell 173 (1), 260-274. e25, 2018
2002018
Molecular mechanism and structure of Trigger Factor bound to the translating ribosome
F Merz, D Boehringer, C Schaffitzel, S Preissler, A Hoffmann, T Maier, ...
The EMBO journal 27 (11), 1622-1632, 2008
1852008
Click chemistry enables preclinical evaluation of targeted epigenetic therapies
DS Tyler, J Vappiani, T Cañeque, EYN Lam, A Ward, O Gilan, YC Chan, ...
Science 356 (6345), 1397-1401, 2017
1312017
Identifying drug targets in tissues and whole blood with thermal-shift profiling
J Perrin, T Werner, N Kurzawa, A Rutkowska, DD Childs, M Kalxdorf, ...
Nature Biotechnology 38 (3), 303-308, 2020
1262020
Association of condensin with chromosomes depends on DNA binding by its HEAT-repeat subunits
I Piazza, A Rutkowska, A Ori, M Walczak, J Metz, V Pelechano, M Beck, ...
Nature structural & molecular biology 21 (6), 560-568, 2014
1242014
Discovery of a first-in-class reversible DNMT1-selective inhibitor with improved tolerability and efficacy in acute myeloid leukemia
MB Pappalardi, K Keenan, M Cockerill, WA Kellner, A Stowell, C Sherk, ...
Nature cancer 2 (10), 1002-1017, 2021
1172021
The C-terminal domain of Escherichia coli trigger factor represents the central module of its chaperone activity
F Merz, A Hoffmann, A Rutkowska, B Zachmann-Brand, B Bukau, ...
Journal of biological chemistry 281 (42), 31963-31971, 2006
1172006
Dynamics of trigger factor interaction with translating ribosomes
A Rutkowska, MP Mayer, A Hoffmann, F Merz, B Zachmann-Brand, ...
Journal of Biological Chemistry 283 (7), 4124-4132, 2008
1112008
Functional Dissection of Escherichia coli Trigger Factor: Unraveling the Function of Individual Domains
G Kramer, A Rutkowska, RD Wegrzyn, H Patzelt, TA Kurz, F Merz, ...
Journal of bacteriology 186 (12), 3777-3784, 2004
1062004
Trigger factor forms a protective shield for nascent polypeptides at the ribosome
A Hoffmann, F Merz, A Rutkowska, B Zachmann-Brand, E Deuerling, ...
Journal of biological chemistry 281 (10), 6539-6545, 2006
1042006
A rapidly reversible chemical dimerizer system to study lipid signaling in living cells
S Feng, V Laketa, F Stein, A Rutkowska, A MacNamara, S Depner, ...
Angewandte Chemie 126 (26), 6838-6841, 2014
812014
A modular probe strategy for drug localization, target identification and target occupancy measurement on single cell level
A Rutkowska, DW Thomson, J Vappiani, T Werner, KM Mueller, L Dittus, ...
ACS chemical biology 11 (9), 2541-2550, 2016
782016
Large-scale purification of ribosome-nascent chain complexes for biochemical and structural studies
A Rutkowska, M Beerbaum, N Rajagopalan, J Fiaux, P Schmieder, ...
Febs Letters 583 (14), 2407-2413, 2009
522009
Condensin: crafting the chromosome landscape
I Piazza, CH Haering, A Rutkowska
Chromosoma 122, 175-190, 2013
472013
Protein tango: the toolbox to capture interacting partners
A Rutkowska, C Schultz
Angewandte Chemie International Edition 51 (33), 8166-8176, 2012
472012
A FlAsH‐Based Cross‐Linker to Study Protein Interactions in Living Cells
A Rutkowska, CH Haering, C Schultz
Angewandte Chemie International Edition 50 (52), 12655-12658, 2011
412011
Characterization of Apo‐Form Selective Inhibition of Indoleamine 2, 3‐Dioxygenase
RF Ortiz‐Meoz, L Wang, R Matico, A Rutkowska‐Klute, M De la Rosa, ...
ChemBioChem 22 (3), 516-522, 2021
242021
T‐CrAsH: A Heterologous Chemical Crosslinker
A Rutkowska, T Plass, JE Hoffmann, DA Yushchenko, S Feng, C Schultz
ChemBioChem 15 (12), 1765-1768, 2014
172014
Synthesis and Evaluation of Novel Ring‐Strained Noncanonical Amino Acids for Residue‐Specific Bioorthogonal Reactions in Living Cells
CD Reinkemeier, C Koehler, PF Sauter, NV Shymanska, C Echalier, ...
Chemistry–A European Journal 27 (19), 6094-6099, 2021
122021
FlAsH‐basierte Verknüpfungen von Proteinen in lebenden Zellen
A Rutkowska, CH Haering, C Schultz
Angewandte Chemie 123 (52), 12867-12870, 2011
92011
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Articles 1–20