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Fernando E Sepulveda
Fernando E Sepulveda
Molecular basis of altered immune homeostasis laboratory, INSERM UMR 1163, Imagine Institute
Bestätigte E-Mail-Adresse bei inserm.fr - Startseite
Titel
Zitiert von
Zitiert von
Jahr
Critical role for asparagine endopeptidase in endocytic Toll-like receptor signaling in dendritic cells
FE Sepulveda, S Maschalidi, R Colisson, L Heslop, C Ghirelli, E Sakka, ...
Immunity 31 (5), 737-748, 2009
3182009
Therapeutic effect of JAK1/2 blockade on the manifestations of hemophagocytic lymphohistiocytosis in mice
S Maschalidi, FE Sepulveda, A Garrigue, A Fischer, G de Saint Basile
Blood, The Journal of the American Society of Hematology 128 (1), 60-71, 2016
1912016
Germline HAVCR2 mutations altering TIM-3 characterize subcutaneous panniculitis-like T cell lymphomas with hemophagocytic lymphohistiocytic syndrome
T Gayden, FE Sepulveda, DA Khuong-Quang, J Pratt, ET Valera, ...
Nature genetics 50 (12), 1650-1657, 2018
1752018
Human RIPK1 deficiency causes combined immunodeficiency and inflammatory bowel diseases
Y Li, M Führer, E Bahrami, P Socha, M Klaudel-Dreszler, A Bouzidi, Y Liu, ...
Proceedings of the National Academy of Sciences 116 (3), 970-975, 2019
1432019
Hemophagocytic syndrome: primary forms and predisposing conditions
FE Sepulveda, G de Saint Basile
Current opinion in immunology 49, 20-26, 2017
1182017
Distinct severity of HLH in both human and murine mutants with complete loss of cytotoxic effector PRF1, RAB27A, and STX11
FE Sepulveda, F Debeurme, G Ménasché, M Kurowska, M Côte, ...
Blood, The Journal of the American Society of Hematology 121 (4), 595-603, 2013
832013
Imprinting of CCR9 on CD4 T cells requires IL-4 signaling on mesenteric lymph node dendritic cells
R Elgueta, FE Sepulveda, F Vilches, L Vargas, JR Mora, MR Bono, ...
The Journal of Immunology 180 (10), 6501-6507, 2008
822008
A novel immunoregulatory role for NK-cell cytotoxicity in protection from HLH-like immunopathology in mice
FE Sepulveda, S Maschalidi, CAJ Vosshenrich, A Garrigue, M Kurowska, ...
Blood, The Journal of the American Society of Hematology 125 (9), 1427-1434, 2015
812015
LYST controls the biogenesis of the endosomal compartment required for secretory lysosome function
FE Sepulveda, A Burgess, X Heiligenstein, N Goudin, MM Ménager, ...
Traffic 16 (2), 191-203, 2015
792015
Graded defects in cytotoxicity determine severity of hemophagocytic lymphohistiocytosis in humans and mice
B Jessen, T Kögl, FE Sepulveda, G de Saint Basile, P Aichele, S Ehl
Frontiers in immunology 4, 71350, 2013
762013
Immune deficiency–related enteropathy-lymphocytopenia-alopecia syndrome results from tetratricopeptide repeat domain 7A deficiency
R Lemoine, J Pachlopnik-Schmid, HF Farin, A Bigorgne, M Debré, ...
Journal of allergy and clinical immunology 134 (6), 1354-1364. e6, 2014
752014
Asparagine endopeptidase controls anti-influenza virus immune responses through TLR7 activation
S Maschalidi, S Hässler, F Blanc, FE Sepulveda, M Tohme, M Chignard, ...
Public Library of Science 8 (8), e1002841, 2012
752012
Conventional dendritic cells require IRAP-Rab14 endosomes for efficient cross-presentation
M Weimershaus, S Maschalidi, F Sepulveda, B Manoury, P van Endert, ...
The Journal of Immunology 188 (4), 1840-1846, 2012
682012
Polygenic mutations in the cytotoxicity pathway increase susceptibility to develop HLH immunopathology in mice
FE Sepulveda, A Garrigue, S Maschalidi, M Garfa-Traore, G Ménasché, ...
Blood, The Journal of the American Society of Hematology 127 (17), 2113-2121, 2016
592016
HAVCR2 mutations are associated with severe hemophagocytic syndrome in subcutaneous panniculitis-like T-cell lymphoma
G Sonigo, M Battistella, M Beylot-Barry, S Ingen-Housz-Oro, N Franck, ...
Blood, The Journal of the American Society of Hematology 135 (13), 1058-1061, 2020
492020
UNC93B1 interacts with the calcium sensor STIM1 for efficient antigen cross-presentation in dendritic cells
S Maschalidi, P Nunes-Hasler, CR Nascimento, I Sallent, V Lannoy, ...
Nature communications 8 (1), 1640, 2017
432017
Dynamic formation of microvillus inclusions during enterocyte differentiation in Munc18-2–deficient intestinal organoids
MH Mosa, O Nicolle, S Maschalidi, FE Sepulveda, A Bidaud-Meynard, ...
Cellular and Molecular Gastroenterology and Hepatology 6 (4), 477-493. e1, 2018
382018
Cytotoxic granule secretion by lymphocytes and its link to immune homeostasis
G de Saint Basile, FE Sepulveda, S Maschalidi, A Fischer
F1000Research 4 (F1000 Faculty Rev), 2015
342015
Efficacy of ruxolitinib in subcutaneous panniculitis-like T-cell lymphoma and hemophagocytic lymphohistiocytosis
R Lévy, M Fusaro, F Guerin, A Chetouani, D Moshous, A Fischer, ...
Blood Advances 4 (7), 1383-1387, 2020
212020
Gene transfer into hematopoietic stem cells reduces HLH manifestations in a murine model of Munc13-4 deficiency
T Soheili, A Durand, FE Sepulveda, J Riviere, C Lagresle-Peyrou, ...
Blood advances 1 (27), 2781-2789, 2017
202017
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