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François Halloy
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RNA‐PROTACs: degraders of RNA‐binding proteins
A Ghidini, A Cléry, F Halloy, FHT Allain, J Hall
Angewandte Chemie 133 (6), 3200-3206, 2021
1192021
Recessive mutations in RTN4IP1 cause isolated and syndromic optic neuropathies
C Angebault, PO Guichet, Y Talmat-Amar, M Charif, S Gerber, ...
The American Journal of Human Genetics 97 (5), 754-760, 2015
622015
Synthesis and cellular activity of stereochemically-pure 2′-O-(2-methoxyethyl)-phosphorothioate oligonucleotides
M Li, HL Lightfoot, F Halloy, AL Malinowska, C Berk, A Behera, ...
Chemical communications 53 (3), 541-544, 2017
512017
WFS1 in optic neuropathies: mutation findings in nonsyndromic optic atrophy and assessment of clinical severity
J Grenier, I Meunier, V Daien, C Baudoin, F Halloy, B Bocquet, C Blanchet, ...
Ophthalmology 123 (9), 1989-1998, 2016
492016
Innovative developments and emerging technologies in RNA therapeutics
F Halloy, A Biscans, KE Bujold, A Debacker, AC Hill, A Lacroix, O Luige, ...
RNA Biology 19 (1), 313-332, 2022
252022
Delta-aminolevulinic acid synthase 2 expression in combination with iron as modifiers of disease severity in erythropoietic protoporphyria
J Barman-Aksözen, F Halloy, PS Iyer, D Schümperli, AE Minder, J Hall, ...
Molecular genetics and metabolism 128 (3), 304-308, 2019
202019
Delivery of oligonucleotides to bone marrow to modulate ferrochelatase splicing in a mouse model of erythropoietic protoporphyria
F Halloy, PS Iyer, P Ćwiek, A Ghidini, J Barman-Aksözen, ...
Nucleic Acids Research 48 (9), 4658-4671, 2020
172020
Chemical synthesis of long RNAs with terminal 5′‐phosphate groups
U Pradère, F Halloy, J Hall
Chemistry–A European Journal 23 (22), 5210-5213, 2017
162017
Repurposing of glycine transport inhibitors for the treatment of erythropoietic protoporphyria
F Halloy, PS Iyer, A Ghidini, V Lysenko, J Barman-Aksözen, ...
Cell Chemical Biology 28 (8), 1221-1234. e6, 2021
112021
Carrier-free gene silencing by amphiphilic nucleic acid conjugates in differentiated intestinal cells
E Moroz, SH Lee, K Yamada, F Halloy, S Martínez-Montero, H Jahns, ...
Molecular Therapy-Nucleic Acids 5, 2016
112016
Increased Affinity of 2′‐O‐(2‐Methoxyethyl)‐Modified Oligonucleotides to RNA through Conjugation of Spermine at Cytidines
E Decuypere, A Lepikhina, F Halloy, J Hall
Helvetica Chimica Acta 102 (12), e1900222, 2019
52019
Efficient Synthesis of 2'-O-Methoxyethyl Oligonucleotide-Cationic Peptide Conjugates
F Halloy, AC Hill, J Hall
ChemMedChem 16 (22), 3391-3395, 2021
42021
Peptide Conjugates of a 2′-O-Methoxyethyl Phosphorothioate Splice-Switching Oligonucleotide Show Increased Entrapment in Endosomes
AC Hill, JP Becker, D Slominski, F Halloy, C Søndergaard, J Ravn, J Hall
ACS omega 8 (43), 40463-40481, 2023
12023
Systemic delivery of a splice-switching oligonucleotide heteroduplex corrects splicing in central nervous system and muscle in spinal muscular atrophy mice
F Halloy, N Ahlskog, M Wood
bioRxiv, 2024.01. 24.577012, 2024
2024
Analysis of Oligonucleotide Biodistribution and Metabolization in Experimental Animals (in Alternative splicing pp335-350)
J Hall, D Schümperli, F Halloy
Methods in Molecular Biology 2537, 2022
2022
Analysis of Oligonucleotide Biodistribution and Metabolization in Experimental Animals
F Halloy, P Brönnimann, J Hall, D Schümperli
Alternative Splicing: Methods and Protocols, 335-350, 2022
2022
Therapeutic Strategies for the Treatment of Erythropoietic Protoporphyria
F Halloy
ETH Zurich, 2020
2020
Genetic analyses of autosomal optic neuropathies reveal novel physiopathological pathways involved in optic nerve degeneration
G Lenaers, F Halloy, N Hieu, C Megy, C Delettre, I Meunier, A Roubertie, ...
Acta Ophthalmologica 91, 2013
2013
New candidate genes for inherited optic atrophy
C Delettre, M Hebrard, F Halloy, C Hamel, G Lenaers
Investigative Ophthalmology & Visual Science 54 (15), 1356-1356, 2013
2013
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