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Aaron A. Thompson
Aaron A. Thompson
The Janssen Pharmaceutical Companies of Johnson & Johnson
Verified email at its.jnj.com
Title
Cited by
Cited by
Year
Structure of the human κ-opioid receptor in complex with JDTic
H Wu, D Wacker, M Mileni, V Katritch, GW Han, E Vardy, W Liu, ...
Nature 485 (7398), 327-332, 2012
10762012
Structural basis for allosteric regulation of GPCRs by sodium ions
W Liu, E Chun, AA Thompson, P Chubukov, F Xu, V Katritch, GW Han, ...
Science 337 (6091), 232-236, 2012
10022012
Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimetic
AA Thompson, W Liu, E Chun, V Katritch, H Wu, E Vardy, XP Huang, ...
Nature 485 (7398), 395-399, 2012
5902012
Molecular control of δ-opioid receptor signalling
G Fenalti, PM Giguere, V Katritch, XP Huang, AA Thompson, V Cherezov, ...
Nature 506 (7487), 191-196, 2014
5372014
Fusion partner toolchest for the stabilization and crystallization of G protein-coupled receptors
E Chun, AA Thompson, W Liu, CB Roth, MT Griffith, V Katritch, J Kunken, ...
Structure 20 (6), 967-976, 2012
4412012
Structural basis for proteolysis‐dependent activation of the poliovirus RNA‐dependent RNA polymerase
AA Thompson, OB Peersen
The EMBO journal 23 (17), 3462-3471, 2004
2762004
GPCR stabilization using the bicelle-like architecture of mixed sterol-detergent micelles
AA Thompson, JJ Liu, E Chun, D Wacker, H Wu, V Cherezov, RC Stevens
Methods 55 (4), 310-317, 2011
1052011
Analysis of flavivirus NS5 methyltransferase cap binding
BJ Geiss, AA Thompson, AJ Andrews, RL Sons, HH Gari, SM Keenan, ...
Journal of molecular biology 385 (5), 1643-1654, 2009
1042009
A single-domain llama antibody potently inhibits the enzymatic activity of botulinum neurotoxin by binding to the non-catalytic α-exosite binding region
J Dong, AA Thompson, Y Fan, J Lou, F Conrad, M Ho, M Pires-Alves, ...
Journal of molecular biology 397 (4), 1106-1118, 2010
982010
The importance of ligand-receptor conformational pairs in stabilization: spotlight on the N/OFQ G protein-coupled receptor
RL Miller, AA Thompson, C Trapella, R Guerrini, D Malfacini, N Patel, ...
Structure 23 (12), 2291-2299, 2015
862015
Stabilization of poliovirus polymerase by NTP binding and fingers–thumb interactions
AA Thompson, RA Albertini, OB Peersen
Journal of molecular biology 366 (5), 1459-1474, 2007
812007
Biochemical characterization of recombinant hepatitis C virus nonstructural protein 4B: evidence for ATP/GTP hydrolysis and adenylate kinase activity
AA Thompson, A Zou, J Yan, R Duggal, W Hao, D Molina, CN Cronin, ...
Biochemistry 48 (5), 906-916, 2009
772009
Structural Characterization of Three Novel Hydroxamate-Based Zinc Chelating Inhibitors of the Clostridium botulinum Serotype A Neurotoxin Light Chain …
AA Thompson, GS Jiao, S Kim, A Thai, L Cregar-Hernandez, ...
Biochemistry 50 (19), 4019-4028, 2011
392011
Nucleotide channel of RNA-dependent RNA polymerase used for intermolecular uridylylation of protein primer
AB Tellez, S Crowder, JF Spagnolo, AA Thompson, OB Peersen, ...
Journal of molecular biology 357 (2), 665-675, 2006
352006
Synthesis and properties of dodecyl trehaloside detergents for membrane protein studies
H Tao, Y Fu, A Thompson, SC Lee, N Mahoney, RC Stevens, Q Zhang
Langmuir 28 (30), 11173-11181, 2012
252012
Composition and process for the generation of a clear or translucent emissive coating
N Smith, CJ Gruszka, A Thompson, M Deemer
US Patent 11,142,654, 2021
232021
Novel fusion partners for the purpose of crystallizing g-protein coupled receptors
MA Hanson, CB Roth, RC Stevens, JM Kunken, MT Griffith, AA Thompson, ...
US Patent App. 13/470,104, 2012
102012
Method for rapid optimization of recombinant GPCR protein expression and stability using virus-like particles
TT Ho, JT Nguyen, J Liu, P Stanczak, AA Thompson, YG Yan, J Chen, ...
Protein Expression and Purification 133, 41-49, 2017
92017
Identification of small-molecule protein–protein interaction inhibitors for NKG2D
AA Thompson, MB Harbut, PP Kung, NK Karpowich, JD Branson, ...
Proceedings of the National Academy of Sciences 120 (18), e2216342120, 2023
32023
Full wwPDB X-ray Structure Validation Report i
H Wang, E Gouaux
Word wide protein data bank, 2009
22009
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