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Kyle Jeffrie Gaulton
Kyle Jeffrie Gaulton
Winkler Endowed Chair in Type 1 Diabetes; Associate Professor of Pediatrics, UCSD
Adresse e-mail validée de ucsd.edu - Page d'accueil
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The genetic architecture of type 2 diabetes
C Fuchsberger, J Flannick, TM Teslovich, A Mahajan, V Agarwala, ...
Nature 536 (7614), 41-47, 2016
12302016
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility
DIAbetes Genetics Replication And Meta-analysis (DIAGRAM) Consortium
Nature genetics 46 (3), 234-244, 2014
8912014
An expanded genome-wide association study of type 2 diabetes in Europeans
RA Scott, LJ Scott, R Mägi, L Marullo, KJ Gaulton, M Kaakinen, ...
Diabetes 66 (11), 2888-2902, 2017
7132017
A map of open chromatin in human pancreatic islets
KJ Gaulton, T Nammo, L Pasquali, JM Simon, PG Giresi, MP Fogarty, ...
Nature genetics 42 (3), 255-259, 2010
6422010
Pancreatic islet enhancer clusters enriched in type 2 diabetes risk-associated variants
L Pasquali, KJ Gaulton, SA Rodríguez-Seguí, L Mularoni, ...
Nature genetics 46 (2), 136-143, 2014
5592014
Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics
C Muus, MD Luecken, G Eraslan, L Sikkema, A Waghray, G Heimberg, ...
Nature medicine 27 (3), 546-559, 2021
540*2021
Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance
LA Lotta, P Gulati, FR Day, F Payne, H Ongen, M Van De Bunt, ...
Nature genetics 49 (1), 17-26, 2017
5252017
Genome-wide associations for birth weight and correlations with adult disease
M Horikoshi, RN Beaumont, FR Day, NM Warrington, MN Kooijman, ...
Nature 538 (7624), 248-252, 2016
4552016
Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors
NM Warrington, RN Beaumont, M Horikoshi, FR Day, Ø Helgeland, ...
Nature genetics 51 (5), 804-814, 2019
4472019
Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: a soft clustering analysis
MS Udler, J Kim, M von Grotthuss, S Bonàs-Guarch, JB Cole, J Chiou, ...
PLoS medicine 15 (9), e1002654, 2018
4222018
Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci
KJ Gaulton, T Ferreira, Y Lee, A Raimondo, R Mägi, ME Reschen, ...
Nature genetics 47 (12), 1415-1425, 2015
4072015
Detection of human adaptation during the past 2000 years
Y Field, EA Boyle, N Telis, Z Gao, KJ Gaulton, D Golan, L Yengo, ...
Science 354 (6313), 760-764, 2016
3832016
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation
A Mahajan, CN Spracklen, W Zhang, MCY Ng, LE Petty, H Kitajima, ...
Nature genetics 54 (5), 560-572, 2022
287*2022
An atlas of dynamic chromatin landscapes in mouse fetal development
DU Gorkin, I Barozzi, Y Zhao, Y Zhang, H Huang, AY Lee, B Li, J Chiou, ...
Nature 583 (7818), 744-751, 2020
2732020
Whole-exome sequencing identifies rare and low-frequency coding variants associated with LDL cholesterol
LA Lange, Y Hu, H Zhang, C Xue, EM Schmidt, ZZ Tang, C Bizon, ...
The American Journal of Human Genetics 94 (2), 233-245, 2014
2352014
The miRNA profile of human pancreatic islets and beta-cells and relationship to type 2 diabetes pathogenesis
M van de Bunt, KJ Gaulton, L Parts, I Moran, PR Johnson, CM Lindgren, ...
PloS one 8 (1), e55272, 2013
2312013
Choice of transcripts and software has a large effect on variant annotation
DJ McCarthy, P Humburg, A Kanapin, MA Rivas, K Gaulton, ...
Genome medicine 6, 1-16, 2014
2242014
A single-cell atlas of chromatin accessibility in the human genome
K Zhang, JD Hocker, M Miller, X Hou, J Chiou, OB Poirion, Y Qiu, YE Li, ...
Cell 184 (24), 5985-6001. e19, 2021
2062021
Interpreting type 1 diabetes risk with genetics and single-cell epigenomics
J Chiou, RJ Geusz, ML Okino, JY Han, M Miller, R Melton, E Beebe, ...
Nature 594 (7863), 398-402, 2021
1922021
Transcript expression data from human islets links regulatory signals from genome-wide association studies for type 2 diabetes and glycemic traits to their downstream effectors
M van de Bunt, JE Manning Fox, X Dai, A Barrett, C Grey, L Li, AJ Bennett, ...
PLoS genetics 11 (12), e1005694, 2015
1852015
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