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Eleanor H. Simpson
Eleanor H. Simpson
Bestätigte E-Mail-Adresse bei columbia.edu
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Transient and selective overexpression of dopamine D2 receptors in the striatum causes persistent abnormalities in prefrontal cortex functioning
C Kellendonk, EH Simpson, HJ Polan, G Malleret, S Vronskaya, V Winiger, ...
Neuron 49 (4), 603-615, 2006
6122006
A possible role for the striatum in the pathogenesis of the cognitive symptoms of schizophrenia
EH Simpson, C Kellendonk, E Kandel
Neuron 65 (5), 585-596, 2010
5382010
Genetic evidence for the bidirectional modulation of synaptic plasticity in the prefrontal cortex by D1 receptors
YY Huang, E Simpson, C Kellendonk, ER Kandel
Proceedings of the National Academy of Sciences 101 (9), 3236-3241, 2004
2752004
Transient overexpression of striatal D2 receptors impairs operant motivation and interval timing
MR Drew, EH Simpson, C Kellendonk, WG Herzberg, O Lipatova, ...
Journal of Neuroscience 27 (29), 7731-7739, 2007
2382007
COMT genotype predicts cortical-limbic D1 receptor availability measured with [11C] NNC112 and PET
M Slifstein, B Kolachana, EH Simpson, P Tabares, B Cheng, M Duvall, ...
Molecular psychiatry 13 (8), 821-827, 2008
2332008
Increasing dopamine D2 receptor expression in the adult nucleus accumbens enhances motivation
P Trifilieff, B Feng, E Urizar, V Winiger, RD Ward, KM Taylor, D Martinez, ...
Molecular psychiatry 18 (9), 1025, 2013
2282013
The behavioral neuroscience of motivation: an overview of concepts, measures, and translational applications
EH Simpson, PD Balsam
Behavioral neuroscience of motivation, 1-12, 2016
1672016
Modeling cognitive endophenotypes of schizophrenia in mice
C Kellendonk, EH Simpson, ER Kandel
Trends in neurosciences 32 (6), 347-358, 2009
1602009
Neural substrates underlying effort, time, and risk-based decision making in motivated behavior
MR Bailey, EH Simpson, PD Balsam
Neurobiology of Learning and Memory 133, 233-256, 2016
1212016
DRD2 C957T polymorphism interacts with the COMT Val158Met polymorphism in human working memory ability
H Xu, CB Kellendonk, EH Simpson, JG Keilp, GE Bruder, HJ Polan, ...
Schizophrenia research 90 (1-3), 104-107, 2007
1182007
Dissociation of hedonic reaction to reward and incentive motivation in an animal model of the negative symptoms of schizophrenia
RD Ward, EH Simpson, VL Richards, G Deo, K Taylor, JI Glendinning, ...
Neuropsychopharmacology 37 (7), 1699-1707, 2012
1122012
Using conditional mutagenesis to study the brain
A Morozov, C Kellendonk, E Simpson, F Tronche
Biological psychiatry 54 (11), 1125-1133, 2003
972003
Pharmacologic rescue of motivational deficit in an animal model of the negative symptoms of schizophrenia
EH Simpson, C Kellendonk, RD Ward, V Richards, O Lipatova, S Fairhurst, ...
Biological psychiatry 69 (10), 928-935, 2011
962011
Impaired timing precision produced by striatal D2 receptor overexpression is mediated by cognitive and motivational deficits.
RD Ward, C Kellendonk, EH Simpson, O Lipatova, MR Drew, S Fairhurst, ...
Behavioral neuroscience 123 (4), 720, 2009
952009
D2 receptor overexpression in the striatum leads to a deficit in inhibitory transmission and dopamine sensitivity in mouse prefrontal cortex
YC Li, C Kellendonk, EH Simpson, ER Kandel, WJ Gao
Proceedings of the National Academy of Sciences 108 (29), 12107-12112, 2011
862011
Transient and selective overexpression of D2 receptors in the striatum causes persistent deficits in conditional associative learning
ME Bach, EH Simpson, L Kahn, JJ Marshall, ER Kandel, C Kellendonk
Proceedings of the National Academy of Sciences 105 (41), 16027-16032, 2008
742008
Schizophrenia in translation: dissecting motivation in schizophrenia and rodents
EH Simpson, JA Waltz, C Kellendonk, PD Balsam
Schizophrenia bulletin 38 (6), 1111-1117, 2012
682012
The mouse Cer1 (Cerberus related or homologue) gene is not required for anterior pattern formation
EH Simpson, DK Johnson, P Hunsicker, R Suffolk, SA Jordan, IJ Jackson
Developmental Biology 213 (1), 202-206, 1999
671999
Increased dopamine D2 receptor activity in the striatum alters the firing pattern of dopamine neurons in the ventral tegmental area
S Krabbe, J Duda, J Schiemann, C Poetschke, G Schneider, ER Kandel, ...
Proceedings of the National Academy of Sciences 112 (12), E1498-E1506, 2015
662015
Selective overexpression of dopamine D3 receptors in the striatum disrupts motivation but not cognition
EH Simpson, V Winiger, DK Biezonski, I Haq, ER Kandel, C Kellendonk
Biological psychiatry 76 (10), 823-831, 2014
592014
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