Joakim Näsvall
Joakim Näsvall
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Real-time evolution of new genes by innovation, amplification, and divergence
J Näsvall, L Sun, JR Roth, DI Andersson
Science 338, 384–387, 2012
Evolution of new functions de novo and from preexisting genes
DI Andersson, J Jerlström-Hultqvist, J Näsvall
Cold Spring Harbor perspectives in biology 7 (6), a017996, 2015
The modified wobble nucleoside uridine-5-oxyacetic acid in tRNAProcmo5UGG promotes reading of all four proline codons in vivo
Rna 10 (10), 1662-1673, 2004
Evolution of antibiotic resistance without antibiotic exposure
A Knöppel, J Näsvall, DI Andersson
Antimicrobial agents and chemotherapy 61 (11), 2017
Activation of cryptic aminoglycoside resistance in Salmonella enterica
S Koskiniemi, M Pränting, E Gullberg, J Näsvall, DI Andersson
Molecular microbiology 80 (6), 1464-1478, 2011
The wobble hypothesis revisited: uridine-5-oxyacetic acid is critical for reading of G-ending codons
SJ Näsvall, P Chen, GR Björk
Rna 13 (12), 2151-2164, 2007
Genetic adaptation to growth under laboratory conditions in Escherichia coli and Salmonella enterica
A Knöppel, M Knopp, LM Albrecht, E Lundin, U Lustig, J Näsvall, ...
Frontiers in microbiology 9, 756, 2018
Minor fitness costs in an experimental model of horizontal gene transfer in bacteria
A Knöppel, PA Lind, U Lustig, J Näsvall, DI Andersson
Molecular biology and evolution 31 (5), 1220-1227, 2014
A'gain of function'mutation in a protein mediates production of novel modified nucleosides
P Chen, PF Crain, SJ Näsvall, SC Pomerantz, GR Björk
The EMBO journal 24 (10), 1842-1851, 2005
Compensating the fitness costs of synonymous mutations
A Knöppel, J Näsvall, DI Andersson
Molecular biology and evolution 33 (6), 1461-1477, 2016
Duplication-insertion recombineering: a fast and scar-free method for efficient transfer of multiple mutations in bacteria
J Näsvall, A Knöppel, DI Andersson
Nucleic acids research 45 (5), e33-e33, 2017
The ribosomal grip of the peptidyl-tRNA is critical for reading frame maintenance
SJ Näsvall, K Nilsson, GR Björk
Journal of molecular biology 385 (2), 350-367, 2009
Structural mechanism of AadA, a dual-specificity aminoglycoside adenylyltransferase from Salmonella enterica
AL Stern, SE Van der Verren, J Näsvall, H Gutiérrez-de-Terán, M Selmer
Journal of Biological Chemistry 293 (29), 11481-11490, 2018
Structural and functional innovations in the real-time evolution of new (βα) 8 barrel enzymes
MS Newton, X Guo, A Söderholm, J Näsvall, P Lundström, DI Andersson, ...
Proceedings of the National Academy of Sciences 114 (18), 4727-4732, 2017
Direct and Inverted Repeat stimulated excision (DIRex): Simple, single-step, and scar-free mutagenesis of bacterial genes
J Näsvall
PLOS One 12 (8), e0184126, 2017
Experimental determination and prediction of the fitness effects of random point mutations in the biosynthetic enzyme HisA
E Lundin, PC Tang, L Guy, J Näsvall, DI Andersson
Molecular biology and evolution 35 (3), 704-718, 2018
Structure of AadA from Salmonella enterica: a monomeric aminoglycoside (3′′)(9) adenyltransferase
Y Chen, J Näsvall, S Wu, DI Andersson, M Selmer
Acta Crystallographica Section D: Biological Crystallography 71 (11), 2267-2277, 2015
Two-step ligand binding in a (βα)8 barrel enzyme – substrate-bound structures shed new light on the catalytic cycle of HisA
A Söderholm, X Guo, MS Newton, GB Evans, J Näsvall, WM Patrick, ...
Journal of Biological Chemistry, 2015
Two groups of phenylalanine biosynthetic operon leader peptides genes: a high level of apparently incidental frameshifting in decoding Escherichia coli pheL
OL Gurvich, SJ Näsvall, PV Baranov, GR Björk, JF Atkins
Nucleic acids research 39 (8), 3079-3092, 2011
Mutational Pathways and Trade-Offs Between HisA and TrpF Functions: Implications for Evolution via Gene Duplication and Divergence
E Lundin, J Näsvall, DI Andersson
Frontiers in microbiology 11, 2516, 2020
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