Sarah Mundt
Sarah Mundt
Institute of Experimental Immunology, University of Zurich
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Conventional DCs sample and present myelin antigens in the healthy CNS and allow parenchymal T cell entry to initiate neuroinflammation
S Mundt, D Mrdjen, SG Utz, M Greter, B Schreiner, B Becher
Science immunology 4 (31), eaau8380, 2019
Inhibition of the immunoproteasome ameliorates experimental autoimmune encephalomyelitis
M Basler, S Mundt, T Muchamuel, C Moll, J Jiang, M Groettrup, CJ Kirk
EMBO molecular medicine 6 (2), 226-238, 2014
The immunoproteasome: a novel drug target for autoimmune diseases
M Basler, S Mundt, A Bitzer, C Schmidt, M Gröttrup
Clin Exp Rheumatol 33 (4 Suppl 92), S74-9, 2015
ATG-dependent phagocytosis in dendritic cells drives myelin-specific CD4+ T cell pathogenicity during CNS inflammation
CW Keller, C Sina, MB Kotur, G Ramelli, S Mundt, I Quast, LA Ligeon, ...
Proceedings of the National Academy of Sciences 114 (52), E11228-E11237, 2017
The CNS immune landscape from the viewpoint of a T cell
S Mundt, M Greter, A Flügel, B Becher
Trends in neurosciences 42 (10), 667-679, 2019
Twin study reveals non-heritable immune perturbations in multiple sclerosis
F Ingelfinger, LA Gerdes, V Kavaka, S Krishnarajah, E Friebel, E Galli, ...
Nature 603 (7899), 152-158, 2022
Inhibition and deficiency of the immunoproteasome subunit LMP7 attenuates LCMV‐induced meningitis
S Mundt, B Engelhardt, CJ Kirk, M Groettrup, M Basler
European journal of immunology 46 (1), 104-113, 2016
CYBB/NOX2 in conventional DCs controls T cell encephalitogenicity during neuroinflammation
CW Keller, MB Kotur, S Mundt, N Dokalis, LA Ligeon, AM Shah, M Prinz, ...
Autophagy 17 (5), 1244-1258, 2021
Inhibiting the immunoproteasome exacerbates the pathogenesis of systemic Candida albicans infection in mice
S Mundt, M Basler, S Buerger, H Engler, M Groettrup
Scientific reports 6 (1), 19434, 2016
Single-cell profiling of myasthenia gravis identifies a pathogenic T cell signature
F Ingelfinger, S Krishnarajah, M Kramer, SG Utz, E Galli, M Lutz, P Zwicky, ...
Acta neuropathologica 141, 901-915, 2021
The ubiquitin-like modifier FAT10 is selectively expressed in medullary thymic epithelial cells and modifies T cell selection
S Buerger, VL Herrmann, S Mundt, N Trautwein, M Groettrup, M Basler
The Journal of Immunology 195 (9), 4106-4116, 2015
Keratinocytes control skin immune homeostasis through de novo–synthesized glucocorticoids
TS Phan, L Schink, J Mann, VM Merk, P Zwicky, S Mundt, D Simon, ...
Science Advances 7 (5), eabe0337, 2021
The immunoproteasome subunit LMP7 is required in the murine thymus for filling up a hole in the T cell repertoire
M Basler, S Mundt, M Groettrup
European journal of immunology 48 (3), 419-429, 2018
The CNS mononuclear phagocyte system in health and disease
S Mundt, M Greter, B Becher
Neuron 110 (21), 3497-3512, 2022
Single-cell profiling of immune system alterations in lymphoid, barrier and solid tissues in aged mice
S Krishnarajah, F Ingelfinger, E Friebel, D Cansever, A Amorim, ...
Nature Aging 2 (1), 74-89, 2022
IL-12 regulates type 3 immunity through interfollicular keratinocytes in psoriasiform inflammation
P Zwicky, F Ingelfinger, BM Silva de Melo, F Ruchti, S Schärli, N Puertas, ...
Science immunology 6 (64), eabg9012, 2021
Analgesia in mice with experimental meningitis reduces pain without altering immune parameters
S Mundt, M Groettrup, M Basler
ALTEX-Alternatives to animal experimentation 32 (3), 183-189, 2015
No prolongation of skin allograft survival by immunoproteasome inhibition in mice
S Mundt, M Basler, B Sawitzki, M Groettrup
Molecular immunology 88, 32-37, 2017
Azathioprine therapy induces selective NK cell depletion and IFN-γ deficiency predisposing to herpesvirus reactivation
F Ingelfinger, C Sparano, D Bamert, D Reyes-Leiva, A Sethi, ...
Journal of Allergy and Clinical Immunology 151 (1), 280-286. e2, 2023
The dural sinus hub: more than just a brain drain
S Mundt, A Keller, M Greter
Cell 184 (4), 858-860, 2021
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