Suivre
Lawrence Heisler
Lawrence Heisler
Ontario Institute of Cancer Research
Adresse e-mail validée de oicr.on.ca
Titre
Citée par
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Année
Pan-cancer analysis of whole genomes
Nature 578 (7793), 82-93, 2020
1686*2020
Prediction of acute myeloid leukaemia risk in healthy individuals
S Abelson, G Collord, SWK Ng, O Weissbrod, N Mendelson Cohen, ...
Nature 559 (7714), 400-404, 2018
7802018
Genomic hallmarks of localized, non-indolent prostate cancer
M Fraser, VY Sabelnykova, TN Yamaguchi, LE Heisler, J Livingstone, ...
Nature 541 (7637), 359-364, 2017
5942017
Tracing the origins of relapse in acute myeloid leukaemia to stem cells
LI Shlush, A Mitchell, L Heisler, S Abelson, SWK Ng, A Trotman-Grant, ...
Nature 547 (7661), 104-108, 2017
5612017
A renewed model of pancreatic cancer evolution based on genomic rearrangement patterns
F Notta, M Chan-Seng-Yue, M Lemire, Y Li, GW Wilson, AA Connor, ...
Nature 538 (7625), 378-382, 2016
5582016
Molecular landmarks of tumor hypoxia across cancer types
V Bhandari, C Hoey, LY Liu, E Lalonde, J Ray, J Livingstone, R Lesurf, ...
Nature genetics 51 (2), 308-318, 2019
5242019
Genotype to phenotype: a complex problem
RD Dowell, O Ryan, A Jansen, D Cheung, S Agarwala, T Danford, ...
Science 328 (5977), 469-469, 2010
4542010
Quantitative phenotyping via deep barcode sequencing
AM Smith, LE Heisler, J Mellor, F Kaper, MJ Thompson, M Chee, FP Roth, ...
Genome research 19 (10), 1836-1842, 2009
3632009
Childhood cerebellar tumours mirror conserved fetal transcriptional programs
MC Vladoiu, I El-Hamamy, LK Donovan, H Farooq, BL Holgado, ...
Nature 572 (7767), 67-73, 2019
3562019
Widespread and functional RNA circularization in localized prostate cancer
S Chen, V Huang, X Xu, J Livingstone, F Soares, J Jeon, Y Zeng, JT Hua, ...
Cell 176 (4), 831-843. e22, 2019
3442019
A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing
TS Alioto, I Buchhalter, S Derdak, B Hutter, MD Eldridge, E Hovig, ...
Nature communications 6 (1), 1-13, 2015
3232015
Highly-multiplexed barcode sequencing: an efficient method for parallel analysis of pooled samples
AM Smith, LE Heisler, RP St. Onge, E Farias-Hesson, IM Wallace, ...
Nucleic acids research 38 (13), e142-e142, 2010
2662010
Mapping the cellular response to small molecules using chemogenomic fitness signatures
AY Lee, RP St. Onge, MJ Proctor, IM Wallace, AH Nile, PA Spagnuolo, ...
Science 344 (6180), 208-211, 2014
2632014
The evolutionary landscape of localized prostate cancers drives clinical aggression
SMG Espiritu, LY Liu, Y Rubanova, V Bhandari, EM Holgersen, LM Szyca, ...
Cell 173 (4), 1003-1013. e15, 2018
2282018
Germline BRCA2 mutations drive prostate cancers with distinct evolutionary trajectories
RA Taylor, M Fraser, J Livingstone, SMG Espiritu, H Thorne, V Huang, ...
Nature communications 8 (1), 13671, 2017
2282017
Distinct Transcriptional Profiles in Ex Vivo CD4+ and CD8+ T Cells Are Established Early in Human Immunodeficiency Virus Type 1 Infection and Are Characterized by a …
MD Hyrcza, C Kovacs, M Loutfy, R Halpenny, L Heisler, S Yang, O Wilkins, ...
Journal of virology 81 (7), 3477-3486, 2007
2062007
Androgen-dependent cell cycle arrest and apoptotic death in PC-3 prostatic cell cultures expressing a full-length human androgen receptor
LE Heisler, A Evangelou, AM Lew, J Trachtenberg, HP Elsholtz, TJ Brown
Molecular and cellular endocrinology 126 (1), 59-73, 1997
2051997
Genomic DNA functions as a universal external standard in quantitative real-time PCR
JJ Yun, LE Heisler, IIL Hwang, O Wilkins, SK Lau, M Hyrcza, ...
Nucleic acids research 34 (12), e85-e85, 2006
2032006
The proteogenomic landscape of curable prostate cancer
A Sinha, V Huang, J Livingstone, J Wang, NS Fox, N Kurganovs, ...
Cancer Cell 35 (3), 414-427. e6, 2019
1922019
CpG Island microarray probe sequences derived from a physical library are representative of CpG Islands annotated on the human genome
LE Heisler, D Torti, PC Boutros, J Watson, C Chan, N Winegarden, ...
Nucleic acids research 33 (9), 2952-2961, 2005
1222005
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