| DNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activities A Shibata, D Moiani, AS Arvai, J Perry, SM Harding, MM Genois, R Maity, ... Molecular cell 53 (1), 7-18, 2014 | 615 | 2014 |
| Mre11 dimers coordinate DNA end bridging and nuclease processing in double-strand-break repair RS Williams, G Moncalian, JS Williams, Y Yamada, O Limbo, DS Shin, ... Cell 135 (1), 97-109, 2008 | 566 | 2008 |
| Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death JH Houl, Z Ye, CA Brosey, LPF Balapiti-Modarage, S Namjoshi, A Bacolla, ... Nature communications 10 (1), 5654, 2019 | 91 | 2019 |
| Supramolecular sensing with phosphonate cavitands M Melegari, M Suman, L Pirondini, D Moiani, C Massera, F Ugozzoli, ... Chemistry–A European Journal 14 (19), 5772-5779, 2008 | 88 | 2008 |
| MRE11 facilitates the removal of human topoisomerase II complexes from genomic DNA KC Lee, K Padget, H Curtis, IG Cowell, D Moiani, Z Sondka, NJ Morris, ... Biology open 1 (9), 863-873, 2012 | 83 | 2012 |
| Structural characterization of a Protein A mimetic peptide dendrimer bound to human IgG D Moiani, M Salvalaglio, C Cavallotti, A Bujacz, I Redzynia, G Bujacz, ... The Journal of Physical Chemistry B 113 (50), 16268-16275, 2009 | 58 | 2009 |
| RNF 4 interacts with both SUMO and nucleosomes to promote the DNA damage response LM Groocock, M Nie, J Prudden, D Moiani, T Wang, A Cheltsov, ... EMBO reports 15 (5), 601-608, 2014 | 51 | 2014 |
| Crystal structure of the first eubacterial Mre11 nuclease reveals novel features that may discriminate substrates during DNA repair D Das, D Moiani, HL Axelrod, MD Miller, D McMullan, KK Jin, P Abdubek, ... Journal of molecular biology 397 (3), 647-663, 2010 | 46 | 2010 |
| p38α MAP kinase C-terminal domain binding pocket characterized by crystallographic and computational analyses JJP Perry, RM Harris, D Moiani, AJ Olson, JA Tainer Journal of molecular biology 391 (1), 1-11, 2009 | 46 | 2009 |
| Targeting SARS-CoV-2 Nsp3 macrodomain structure with insights from human poly (ADP-ribose) glycohydrolase (PARG) structures with inhibitors CA Brosey, JH Houl, P Katsonis, LPF Balapiti-Modarage, S Bommagani, ... Progress in Biophysics and Molecular Biology 163, 171-186, 2021 | 43 | 2021 |
| Vitamin E enhances cancer immunotherapy by reinvigorating dendritic cells via targeting checkpoint SHP1 X Yuan, Y Duan, Y Xiao, K Sun, Y Qi, Y Zhang, Z Ahmed, D Moiani, J Yao, ... Cancer discovery 12 (7), 1742-1759, 2022 | 42 | 2022 |
| Molecular dynamic investigation of the interaction of supported affinity ligands with monoclonal antibodies L Zamolo, V Busini, D Moiani, D Moscatelli, C Cavallotti Biotechnology progress 24 (3), 527-539, 2008 | 35 | 2008 |
| Investigation of the influence of spacer arm on the structural evolution of affinity ligands supported on agarose V Busini, D Moiani, D Moscatelli, L Zamolo, C Cavallotti The Journal of Physical Chemistry B 110 (46), 23564-23577, 2006 | 33 | 2006 |
| Mre11 ATLD17/18 mutation retains Tel1/ATM activity but blocks DNA double-strand break repair O Limbo, D Moiani, A Kertokalio, C Wyman, JA Tainer, P Russell Nucleic acids research 40 (22), 11435-11449, 2012 | 30 | 2012 |
| GRB2 enforces homology-directed repair initiation by MRE11 Z Ye, S Xu, Y Shi, A Bacolla, A Syed, D Moiani, CL Tsai, Q Shen, G Peng, ... Science Advances 7 (32), eabe9254, 2021 | 26 | 2021 |
| Fragment-and structure-based drug discovery for developing therapeutic agents targeting the DNA Damage Response DM Wilson III, AM Deacon, MAJ Duncton, P Pellicena, MM Georgiadis, ... Progress in biophysics and molecular biology 163, 130-142, 2021 | 25 | 2021 |
| Oxoanion binding by guanidiniocarbonylpyrrole cations in water: A combined DFT and MD investigation D Moiani, C Cavallotti, A Famulari, C Schmuck Chemistry–A European Journal 14 (17), 5207-5219, 2008 | 23 | 2008 |
| Measuring H-bonding in supramolecular complexes by gas phase ion–molecule reactions E Kalenius, D Moiani, E Dalcanale, P Vainiotalo Chemical communications, 3865-3867, 2007 | 23 | 2007 |
| Targeting allostery with avatars to design inhibitors assessed by cell activity: dissecting MRE11 endo-and exonuclease activities D Moiani, DA Ronato, CA Brosey, AS Arvai, A Syed, JY Masson, E Petricci, ... Methods in enzymology 601, 205-241, 2018 | 22 | 2018 |
| An effective human uracil-DNA glycosylase inhibitor targets the open pre-catalytic active site conformation MT Nguyen, D Moiani, Z Ahmed, AS Arvai, S Namjoshi, DS Shin, ... Progress in biophysics and molecular biology 163, 143-159, 2021 | 14 | 2021 |
