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Nadia Terranova
Nadia Terranova
Merck Serono S.A.
Bestätigte E-Mail-Adresse bei merckgroup.com
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The clinical pharmacology of cladribine tablets for the treatment of relapsing multiple sclerosis
R Hermann, MO Karlsson, AM Novakovic, N Terranova, M Fluck, ...
Clinical Pharmacokinetics 58, 283-297, 2019
632019
Application of machine learning in translational medicine: current status and future opportunities
N Terranova, K Venkatakrishnan, LJ Benincosa
The AAPS Journal 23 (4), 74, 2021
502021
Pharmacometrics Markup Language (PharmML): opening new perspectives for model exchange in drug development
MJ Swat, S Moodie, SM Wimalaratne, NR Kristensen, M Lavielle, A Mari, ...
CPT: pharmacometrics & systems pharmacology 4 (6), 316-319, 2015
412015
A predictive pharmacokinetic–pharmacodynamic model of tumor growth kinetics in xenograft mice after administration of anticancer agents given in combination
N Terranova, M Germani, F Del Bene, P Magni
Cancer chemotherapy and pharmacology 72, 471-482, 2013
372013
Mouse embryonic stem cells that survive γ‐rays exposure maintain pluripotent differentiation potential and genome stability
P Rebuzzini, D Pignalosa, G Mazzini, R Di Liberto, A Coppola, ...
Journal of cellular physiology 227 (3), 1242-1249, 2012
332012
Fast screening of covariates in population models empowered by machine learning
E Sibieude, A Khandelwal, JS Hesthaven, P Girard, N Terranova
Journal of Pharmacokinetics and Pharmacodynamics 48 (4), 597-609, 2021
312021
White paper: landscape on technical and conceptual requirements and competence framework in drug/disease modeling and simulation
G Vlasakakis, E Comets, A Keunecke, I Gueorguieva, P Magni, ...
CPT: pharmacometrics & systems pharmacology 2 (5), 1-8, 2013
212013
Population pharmacokinetic model selection assisted by machine learning
E Sibieude, A Khandelwal, P Girard, JS Hesthaven, N Terranova
Journal of Pharmacokinetics and Pharmacodynamics 49 (2), 257-270, 2022
192022
Population pharmacokinetics of ATR inhibitor berzosertib in phase I studies for different cancer types
N Terranova, M Jansen, M Falk, BS Hendriks
Cancer Chemotherapy and Pharmacology 87, 185-196, 2021
182021
Machine learning analysis of individual tumor lesions in four metastatic colorectal cancer clinical studies: linking tumor heterogeneity to overall survival
D Vera-Yunca, P Girard, ZP Parra-Guillen, A Munafo, IF Trocóniz, ...
The AAPS journal 22, 1-12, 2020
182020
Pharmacometric modeling and machine learning analyses of prognostic and predictive factors in the JAVELIN Gastric 100 phase III trial of avelumab
N Terranova, J French, H Dai, M Wiens, A Khandelwal, A Ruiz‐Garcia, ...
CPT: pharmacometrics & systems pharmacology 11 (3), 333-347, 2022
152022
Assessing similarity among individual tumor size lesion dynamics: the CICIL methodology
N Terranova, P Girard, K Ioannou, U Klinkhardt, A Munafo
CPT: pharmacometrics & systems pharmacology 7 (4), 228-236, 2018
142018
Predicting disease activity in patients with multiple sclerosis: An explainable machine‐learning approach in the Mavenclad trials
S Basu, A Munafo, AF Ben‐Amor, S Roy, P Girard, N Terranova
CPT: Pharmacometrics & Systems Pharmacology 11 (7), 843-853, 2022
122022
Model description language (MDL): a standard for modeling and simulation
MK Smith, SL Moodie, R Bizzotto, E Blaudez, E Borella, L Carrara, ...
CPT: pharmacometrics & systems pharmacology 6 (10), 647, 2017
122017
Resistance development: a major piece in the jigsaw puzzle of tumor size modeling
N Terranova, P Girard, U Klinkhardt, A Munafo
CPT: Pharmacometrics & Systems Pharmacology 4 (6), 320-323, 2015
122015
Effects of postponing treatment in the second year of cladribine administration: Clinical trial simulation analysis of absolute lymphocyte counts and relapse rate in patients …
N Terranova, C Hicking, F Dangond, A Munafo
Clinical pharmacokinetics 58, 325-333, 2019
112019
Modeling tumor growth inhibition and toxicity outcome after administration of anticancer agents in xenograft mice: a dynamic energy budget (DEB) approach
N Terranova, EM Tosca, E Borella, E Pesenti, M Rocchetti, P Magni
Journal of theoretical biology 450, 1-14, 2018
112018
A minimal model of tumor growth inhibition in combination regimens under the hypothesis of no interaction between drugs
P Magni, N Terranova, F Del Bene, M Germani, G De Nicolao
IEEE transactions on biomedical engineering 59 (8), 2161-2170, 2012
102012
TGI-Simulator: a visual tool to support the preclinical phase of the drug discovery process by assessing in silico the effect of an anticancer drug
N Terranova, P Magni
Computer methods and programs in biomedicine 105 (2), 162-174, 2012
102012
Artificial intelligence for quantitative modeling in drug discovery and development: an innovation and quality consortium perspective on use cases and best practices
N Terranova, D Renard, MH Shahin, S Menon, Y Cao, CECA Hop, ...
Clinical Pharmacology & Therapeutics 115 (4), 658-672, 2024
92024
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