| Suppression of tumor lymphangiogenesis and lymph node metastasis by blocking vascular endothelial growth factor receptor 3 signaling Y He, K Kozaki, T Karpanen, K Koshikawa, S Yla-Herttuala, T Takahashi, ... Journal of the National Cancer Institute 94 (11), 819-825, 2002 | 720 | 2002 |
| A vascular endothelial growth factor antagonist is produced by the human placenta and released into the maternal circulation DE Clark, SK Smith, Y He, KA Day, DR Licence, AN Corps, R Lammoglia, ... Biology of reproduction 59 (6), 1540-1548, 1998 | 555 | 1998 |
| Vascular endothelial cell growth factor receptor 3–mediated activation of lymphatic endothelium is crucial for tumor cell entry and spread via lymphatic vessels Y He, I Rajantie, K Pajusola, M Jeltsch, T Holopainen, S Yla-Herttuala, ... Cancer research 65 (11), 4739-4746, 2005 | 554 | 2005 |
| Alternative splicing of vascular endothelial growth factor (VEGF)-R1 (FLT-1) pre-mRNA is important for the regulation of VEGF activity Y He, SK Smith, KA Day, DE Clark, DR Licence, DS Charnock-Jones Molecular endocrinology 13 (4), 537-545, 1999 | 344 | 1999 |
| Inhibition of lymphogenous metastasis using adeno-associated virus-mediated gene transfer of a soluble VEGFR-3 decoy receptor JM Lin, AS Lalani, TC Harding, M Gonzalez, WW Wu, B Luan, GH Tu, ... Cancer research 65 (15), 6901-6909, 2005 | 338 | 2005 |
| Role of lymphangiogenic factors in tumor metastasis Y He, T Karpanen, K Alitalo Biochimica Et Biophysica Acta (BBA)-Reviews on Cancer 1654 (1), 3-12, 2004 | 320 | 2004 |
| Normalization of tumor vessels by Tie2 activation and Ang2 inhibition enhances drug delivery and produces a favorable tumor microenvironment JS Park, IK Kim, S Han, I Park, C Kim, J Bae, SJ Oh, S Lee, JH Kim, ... Cancer cell 30 (6), 953-967, 2016 | 309 | 2016 |
| Preexisting lymphatic endothelium but not endothelial progenitor cells are essential for tumor lymphangiogenesis and lymphatic metastasis Y He, I Rajantie, M Ilmonen, T Makinen, MJ Karkkainen, P Haiko, ... Cancer research 64 (11), 3737-3740, 2004 | 273 | 2004 |
| PDGF-D induces macrophage recruitment, increased interstitial pressure, and blood vessel maturation during angiogenesis M Uutela, M Wirzenius, K Paavonen, I Rajantie, Y He, T Karpanen, ... Blood 104 (10), 3198-3204, 2004 | 266 | 2004 |
| Plastic roles of pericytes in the blood–retinal barrier DY Park, J Lee, J Kim, K Kim, S Hong, S Han, Y Kubota, HG Augustin, ... Nature communications 8 (1), 15296, 2017 | 255 | 2017 |
| Meningeal lymphatic vessels regulate brain tumor drainage and immunity X Hu, Q Deng, L Ma, Q Li, Y Chen, Y Liao, F Zhou, C Zhang, L Shao, ... Cell research 30 (3), 229-243, 2020 | 250 | 2020 |
| Distinct vascular endothelial growth factor signals for lymphatic vessel enlargement and sprouting M Wirzenius, T Tammela, M Uutela, Y He, T Odorisio, G Zambruno, ... The Journal of experimental medicine 204 (6), 1431-1440, 2007 | 216 | 2007 |
| Amelioration of sepsis by TIE2 activation–induced vascular protection S Han, SJ Lee, KE Kim, HS Lee, N Oh, I Park, E Ko, SJ Oh, YS Lee, D Kim, ... Science translational medicine 8 (335), 335ra55-335ra55, 2016 | 198 | 2016 |
| Activation of vascular endothelial growth factor receptor-3 in macrophages restrains TLR4-NF-κB signaling and protects against endotoxin shock Y Zhang, Y Lu, L Ma, X Cao, J Xiao, J Chen, S Jiao, Y Gao, C Liu, Z Duan, ... Immunity 40 (4), 501-514, 2014 | 168 | 2014 |
| VEGFR-3 ligand-binding and kinase activity are required for lymphangiogenesis but not for angiogenesis L Zhang, F Zhou, W Han, B Shen, J Luo, M Shibuya, Y He Cell research 20 (12), 1319-1331, 2010 | 159 | 2010 |
| Angiopoietin-2 exacerbates cardiac hypoxia and inflammation after myocardial infarction SJ Lee, C Lee, S Kang, I Park, YH Kim, SK Kim, SP Hong, H Bae, Y He, ... The Journal of clinical investigation 128 (11), 5018-5033, 2018 | 138 | 2018 |
| Akt/Protein kinase B is required for lymphatic network formation, remodeling, and valve development F Zhou, Z Chang, L Zhang, YK Hong, B Shen, B Wang, F Zhang, G Lu, ... The American journal of pathology 177 (4), 2124-2133, 2010 | 110 | 2010 |
| Tie2 expression on macrophages is required for blood vessel reconstruction and tumor relapse after chemotherapy L Chen, J Li, F Wang, C Dai, F Wu, X Liu, T Li, R Glauben, Y Zhang, G Nie, ... Cancer research 76 (23), 6828-6838, 2016 | 97 | 2016 |
| Impaired angiopoietin/Tie2 signaling compromises Schlemm’s canal integrity and induces glaucoma J Kim, DY Park, H Bae, D Kim, C Lee, S Song, TY Chung, DH Lim, ... The Journal of clinical investigation 127 (10), 3877-3896, 2017 | 93 | 2017 |
| Angiopoietin-1 overexpression modulates vascular endothelium to facilitate tumor cell dissemination and metastasis establishment T Holopainen, H Huang, C Chen, KE Kim, L Zhang, F Zhou, W Han, C Li, ... Cancer research 69 (11), 4656-4664, 2009 | 80 | 2009 |
