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Holger Heyn
Holger Heyn
CNAG
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Zitiert von
Zitiert von
Jahr
Global epigenomic reconfiguration during mammalian brain development
R Lister, EA Mukamel, JR Nery, M Urich, CA Puddifoot, ND Johnson, ...
Science 341 (6146), 1237905, 2013
20162013
A landscape of pharmacogenomic interactions in cancer
F Iorio, TA Knijnenburg, DJ Vis, GR Bignell, MP Menden, M Schubert, ...
Cell 166 (3), 740-754, 2016
19572016
Machine learning identifies stemness features associated with oncogenic dedifferentiation
TM Malta, A Sokolov, AJ Gentles, T Burzykowski, L Poisson, JN Weinstein, ...
Cell 173 (2), 338-354. e15, 2018
18662018
Comparative analysis of single-cell RNA sequencing methods
C Ziegenhain, B Vieth, S Parekh, B Reinius, A Guillaumet-Adkins, ...
Molecular cell 65 (4), 631-643. e4, 2017
15742017
Validation of a DNA methylation microarray for 450,000 CpG sites in the human genome
J Sandoval, H Heyn, S Moran, J Serra-Musach, MA Pujana, M Bibikova, ...
Epigenetics 6 (6), 692-702, 2011
12022011
Distinct DNA methylomes of newborns and centenarians
H Heyn, N Li, HJ Ferreira, S Moran, DG Pisano, A Gomez, J Diez, ...
Proceedings of the National Academy of Sciences 109 (26), 10522-10527, 2012
9282012
DNA methylation profiling in the clinic: applications and challenges
H Heyn, M Esteller
Nature Reviews Genetics 13 (10), 679-692, 2012
8862012
SPOTlight: seeded NMF regression to deconvolute spatial transcriptomics spots with single-cell transcriptomes
M Elosua-Bayes, P Nieto, E Mereu, I Gut, H Heyn
Nucleic acids research 49 (9), e50-e50, 2021
4922021
Epigenetic profiling to classify cancer of unknown primary: a multicentre, retrospective analysis
S Moran, A Martínez-Cardús, S Sayols, E Musulén, C Balañá, ...
The Lancet Oncology 17 (10), 1386-1395, 2016
4852016
DNA methylation contributes to natural human variation
H Heyn, S Moran, I Hernando-Herraez, S Sayols, A Gomez, J Sandoval, ...
Genome research 23 (9), 1363-1372, 2013
4602013
Benchmarking single-cell RNA-sequencing protocols for cell atlas projects
E Mereu, A Lafzi, C Moutinho, C Ziegenhain, DJ McCarthy, ...
Nature biotechnology 38 (6), 747-755, 2020
4332020
A prognostic DNA methylation signature for stage I non–small-cell lung cancer
J Sandoval, J Mendez-Gonzalez, E Nadal, G Chen, FJ Carmona, ...
Journal of clinical oncology 31 (32), 4140-4147, 2013
3192013
Robustness and applicability of transcription factor and pathway analysis tools on single-cell RNA-seq data
CH Holland, J Tanevski, J Perales-Patón, J Gleixner, MP Kumar, E Mereu, ...
Genome biology 21, 1-19, 2020
2882020
The emerging landscape of spatial profiling technologies
JR Moffitt, E Lundberg, H Heyn
Nature Reviews Genetics 23 (12), 741-759, 2022
2792022
DNA methylation map of human atherosclerosis
S Zaina, H Heyn, FJ Carmona, N Varol, S Sayols, E Condom, ...
Circulation: Cardiovascular Genetics 7 (5), 692-700, 2014
2782014
Mutations in neutrophil elastase causing congenital neutropenia lead to cytoplasmic protein accumulation and induction of the unfolded protein response
I Köllner, B Sodeik, S Schreek, H Heyn, N von Neuhoff, ...
Blood 108 (2), 493-500, 2006
2352006
Identity noise and adipogenic traits characterize dermal fibroblast aging
MC Salzer, A Lafzi, A Berenguer-Llergo, C Youssif, A Castellanos, ...
Cell 175 (6), 1575-1590. e22, 2018
2282018
Epigenomic analysis detects aberrant super-enhancer DNA methylation in human cancer
H Heyn, E Vidal, HJ Ferreira, M Vizoso, S Sayols, A Gomez, S Moran, ...
Genome biology 17, 1-16, 2016
2242016
Tutorial: guidelines for the experimental design of single-cell RNA sequencing studies
A Lafzi, C Moutinho, S Picelli, H Heyn
Nature protocols 13 (12), 2742-2757, 2018
2162018
Dietary palmitic acid promotes a prometastatic memory via Schwann cells
G Pascual, D Domínguez, M Elosúa-Bayes, F Beckedorff, C Laudanna, ...
Nature 599 (7885), 485-490, 2021
2032021
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