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Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 L Galluzzi, I Vitale, SA Aaronson, JM Abrams, D Adam, P Agostinis, ... Cell Death & Differentiation 25 (3), 486-541, 2018 | 5386 | 2018 |
DRAM, a p53-induced modulator of autophagy, is critical for apoptosis D Crighton, S Wilkinson, J O'Prey, N Syed, P Smith, PR Harrison, ... Cell 126 (1), 121-134, 2006 | 1641 | 2006 |
Molecular definitions of autophagy and related processes L Galluzzi, EH Baehrecke, A Ballabio, P Boya, JM Bravo‐San Pedro, ... The EMBO journal 36 (13), 1811-1836, 2017 | 1523 | 2017 |
The alternative product from the human CDKN2A locus, p14ARF, participates in a regulatory feedback loop with p53 and MDM2 FJ Stott, S Bates, MC James, BB McConnell, M Starborg, S Brookes, ... The EMBO journal 17 (17), 5001-5014, 1998 | 1510 | 1998 |
Autophagy in malignant transformation and cancer progression L Galluzzi, F Pietrocola, JM Bravo‐San Pedro, RK Amaravadi, ... The EMBO journal 34 (7), 856-880, 2015 | 1242 | 2015 |
p53 and metabolism KH Vousden, KM Ryan Nature Reviews Cancer 9 (10), 691-700, 2009 | 1163 | 2009 |
Regulation and function of the p53 tumor suppressor protein KM Ryan, AC Phillips, KH Vousden Current opinion in cell biology 13 (3), 332-337, 2001 | 1026 | 2001 |
Role of NF-κB in p53-mediated programmed cell death KM Ryan, MK Ernst, NR Rice, KH Vousden Nature 404 (6780), 892-897, 2000 | 966 | 2000 |
Autophagy in major human diseases DJ Klionsky, G Petroni, RK Amaravadi, EH Baehrecke, A Ballabio, P Boya, ... The EMBO journal 40 (19), e108863, 2021 | 769 | 2021 |
p53 status determines the role of autophagy in pancreatic tumour development MT Rosenfeldt, J O’Prey, JP Morton, C Nixon, G MacKay, A Mrowinska, ... Nature 504 (7479), 296-300, 2013 | 723 | 2013 |
The multiple roles of autophagy in cancer MT Rosenfeldt, KM Ryan Carcinogenesis 32 (7), 955-963, 2011 | 366 | 2011 |
Mitochondrial inner membrane permeabilisation enables mt DNA release during apoptosis JS Riley, G Quarato, C Cloix, J Lopez, J O'Prey, M Pearson, J Chapman, ... The EMBO journal 37 (17), e99238, 2018 | 364 | 2018 |
Mannose impairs tumour growth and enhances chemotherapy PS Gonzalez, J O’Prey, S Cardaci, VJA Barthet, J Sakamaki, F Beaumatin, ... Nature 563 (7733), 719-723, 2018 | 342 | 2018 |
Induction of DNA synthesis and apoptosis are separable functions of E2F-1. AC Phillips, S Bates, KM Ryan, K Helin, KH Vousden Genes & development 11 (14), 1853-1863, 1997 | 339 | 1997 |
PUMA-and Bax-induced autophagy contributes to apoptosis KS Yee, S Wilkinson, J James, KM Ryan, KH Vousden Cell Death & Differentiation 16 (8), 1135-1145, 2009 | 278 | 2009 |
New frontiers in promoting tumour cell death: targeting apoptosis, necroptosis and autophagy JS Long, KM Ryan Oncogene 31 (49), 5045-5060, 2012 | 277 | 2012 |
Myc oncogenes: the enigmatic family KM Ryan, GD Birnie Biochemical Journal 314 (3), 713-721, 1996 | 274 | 1996 |
The role of autophagy in tumour development and cancer therapy MT Rosenfeldt, KM Ryan Expert reviews in molecular medicine 11, e36, 2009 | 258 | 2009 |
DRAM links autophagy to p53 and programmed cell death D Crighton, S Wilkinson, KM Ryan Autophagy 3 (1), 72-74, 2007 | 253 | 2007 |