| Alleviating cancer drug toxicity by inhibiting a bacterial enzyme BD Wallace, H Wang, KT Lane, JE Scott, J Orans, JS Koo, M Venkatesh, ... Science 330 (6005), 831-835, 2010 | 994 | 2010 |
| Structure and inhibition of microbiome β-glucuronidases essential to the alleviation of cancer drug toxicity BD Wallace, AB Roberts, RM Pollet, JD Ingle, KA Biernat, SJ Pellock, ... Chemistry & biology 22 (9), 1238-1249, 2015 | 249 | 2015 |
| Pharmacologic targeting of bacterial β-glucuronidase alleviates nonsteroidal anti-inflammatory drug-induced enteropathy in mice A LoGuidice, BD Wallace, L Bendel, MR Redinbo, UA Boelsterli Journal of Pharmacology and Experimental Therapeutics 341 (2), 447-454, 2012 | 199 | 2012 |
| Molecular insights into microbial β-glucuronidase inhibition to abrogate CPT-11 toxicity AB Roberts, BD Wallace, MK Venkatesh, S Mani, MR Redinbo Molecular Pharmacology 84 (2), 208-217, 2013 | 143 | 2013 |
| Targeted inhibition of gut bacterial β-glucuronidase activity enhances anticancer drug efficacy AP Bhatt, SJ Pellock, KA Biernat, WG Walton, BD Wallace, BC Creekmore, ... Proceedings of the National Academy of Sciences 117 (13), 7374-7381, 2020 | 141 | 2020 |
| Recognition and repair of chemically heterogeneous structures at DNA ends SN Andres, MJ Schellenberg, BD Wallace, P Tumbale, RS Williams Environmental and molecular mutagenesis 56 (1), 1-21, 2015 | 90 | 2015 |
| Endogenous DNA 3′ blocks are vulnerabilities for BRCA1 and BRCA2 deficiency and are reversed by the APE2 nuclease A Álvarez-Quilón, JL Wojtaszek, MC Mathieu, T Patel, CD Appel, ... Molecular cell 78 (6), 1152-1165. e8, 2020 | 82 | 2020 |
| The human microbiome is a source of therapeutic drug targets BD Wallace, MR Redinbo Current opinion in chemical biology 17 (3), 379-384, 2013 | 76 | 2013 |
| Xenobiotic-sensing nuclear receptors involved in drug metabolism: a structural perspective BD Wallace, MR Redinbo Drug metabolism reviews 45 (1), 79-100, 2013 | 73 | 2013 |
| Characterization of the N-Acetyl-α-d-glucosaminyl l-Malate Synthase and Deacetylase Functions for Bacillithiol Biosynthesis in Bacillus anthracis, D Parsonage, GL Newton, RC Holder, BD Wallace, C Paige, CJ Hamilton, ... Biochemistry 49 (38), 8398-8414, 2010 | 72 | 2010 |
| Structural and functional analysis of the human nuclear xenobiotic receptor PXR in complex with RXRα BD Wallace, L Betts, G Talmage, RM Pollet, NS Holman, MR Redinbo Journal of molecular biology 425 (14), 2561-2577, 2013 | 63 | 2013 |
| Hydration changes accompanying the binding of minor groove ligands with DNA NN Degtyareva, BD Wallace, AR Bryant, KM Loo, JT Petty Biophysical journal 92 (3), 959-965, 2007 | 60 | 2007 |
| APE2 Zf-GRF facilitates 3′-5′ resection of DNA damage following oxidative stress BD Wallace, Z Berman, GA Mueller, Y Lin, T Chang, SN Andres, ... Proceedings of the National Academy of Sciences 114 (2), 304-309, 2017 | 59 | 2017 |
| Targeting the pregnane X receptor using microbial metabolite mimicry Z Dvořák, F Kopp, CM Costello, JS Kemp, H Li, A Vrzalová, M Štěpánková, ... EMBO molecular medicine 12 (4), e11621, 2020 | 55 | 2020 |
| Ribonucleotide triggered DNA damage and RNA-DNA damage responses BD Wallace, RS Williams RNA biology 11 (11), 1340-1346, 2014 | 28 | 2014 |
| A farmer-based approach to sustainable land management by matching enterprises with land capabilities and managing environmental impacts AD Mackay, MG Lambert, MK Krausse, AP Rhodes, BD Wallace, JS Scott New Zealand Research and Development Council, 1999 | 13 | 1999 |
| Structure of the sirtuin‐linked macrodomain SAV0325 from Staphylococcus aureus CD Appel, GK Feld, BD Wallace, RS Williams Protein Science 25 (9), 1682-1691, 2016 | 12 | 2016 |
| Turnover-Dependent Covalent Inactivation of Staphylococcus aureus Coenzyme A-Disulfide Reductase by Coenzyme A-Mimetics: Mechanistic and Structural … BD Wallace, JS Edwards, JR Wallen, WJA Moolman, ... Biochemistry 51 (39), 7699-7711, 2012 | 11 | 2012 |
| Selective beta-glucuronidase inhibitors as a treatment for side effects of camptothecin antineoplastic agents MR Redinbo, S Mani, A Williams, J Scott, LA Yeh, BD Wallace, KT Lane US Patent 8,557,808, 2013 | 5 | 2013 |
| Virtual screening for the discovery of microbiome β-glucuronidase inhibitors to alleviate cancer drug toxicity AP Challa, X Hu, YQ Zhang, J Hymes, BD Wallace, S Karavadhi, H Sun, ... Journal of chemical information and modeling 62 (7), 1783-1793, 2022 | 4 | 2022 |
