| Characterization of ADAMTS-9 and ADAMTS-20 as a distinct ADAMTS subfamily related to Caenorhabditis elegans GON-1 RPT Somerville, JM Longpre, KA Jungers, JM Engle, M Ross, S Evanko, ... Journal of Biological Chemistry 278 (11), 9503-9513, 2003 | 389 | 2003 |
| Combination of high-fat/high-fructose diet and low-dose streptozotocin to model long-term type-2 diabetes complications DA Barrière, C Noll, G Roussy, F Lizotte, A Kessai, K Kirby, K Belleville, ... Scientific Reports 8 (1), 424, 2018 | 151 | 2018 |
| Characterization of proADAMTS5 processing by proprotein convertases JM Longpré, DR McCulloch, BH Koo, JP Alexander, SS Apte, R Leduc The international journal of biochemistry & cell biology 41 (5), 1116-1126, 2009 | 136 | 2009 |
| Discovery and structure–activity relationship of a bioactive fragment of ELABELA that modulates vascular and cardiac functions A Murza, X Sainsily, D Coquerel, J Côté, P Marx, É Besserer-Offroy, ... Journal of medicinal chemistry 59 (7), 2962-2972, 2016 | 133 | 2016 |
| ADAMTS7B, the full-length product of the ADAMTS7 gene, is a chondroitin sulfate proteoglycan containing a mucin domain RPT Somerville, JM Longpré, ED Apel, RM Lewis, LW Wang, JR Sanes, ... Journal of Biological Chemistry 279 (34), 35159-35175, 2004 | 126 | 2004 |
| Conjugation of a brain-penetrant peptide with neurotensin provides antinociceptive properties M Demeule, N Beaudet, A Régina, É Besserer-Offroy, A Murza, ... The Journal of clinical investigation 124 (3), 1199-1213, 2014 | 119 | 2014 |
| Functional selectivity profiling of the angiotensin II type 1 receptor using pathway-wide BRET signaling sensors Y Namkung, C LeGouill, S Kumar, Y Cao, LB Teixeira, V Lukasheva, ... Science signaling 11 (559), eaat1631, 2018 | 118 | 2018 |
| Cell-surface processing of pro-ADAMTS9 by furin BH Koo, JM Longpré, RPT Somerville, JP Alexander, R Leduc, SS Apte Journal of Biological Chemistry 281 (18), 12485-12494, 2006 | 81 | 2006 |
| Stability and degradation patterns of chemically modified analogs of apelin‐13 in plasma and cerebrospinal fluid A Murza, K Belleville, JM Longpré, P Sarret, É Marsault Peptide Science 102 (4), 297-303, 2014 | 77 | 2014 |
| Regulation of ADAMTS9 secretion and enzymatic activity by its propeptide BH Koo, JM Longpré, RPT Somerville, JP Alexander, R Leduc, SS Apte Journal of biological chemistry 282 (22), 16146-16154, 2007 | 75 | 2007 |
| Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs A Luginina, A Gusach, E Marin, A Mishin, R Brouillette, P Popov, ... Science advances 5 (10), eaax2518, 2019 | 74 | 2019 |
| The signaling signature of the neurotensin type 1 receptor with endogenous ligands É Besserer-Offroy, RL Brouillette, S Lavenus, U Froehlich, A Brumwell, ... European journal of pharmacology 805, 1-13, 2017 | 63 | 2017 |
| Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors A Gusach, A Luginina, E Marin, RL Brouillette, É Besserer-Offroy, ... Nature communications 10 (1), 5573, 2019 | 61 | 2019 |
| C-Terminal modifications of apelin-13 significantly change ligand binding, receptor signaling, and hypotensive action A Murza, E Besserer-Offroy, J Cote, P Berube, JM Longpre, R Dumaine, ... Journal of medicinal chemistry 58 (5), 2431-2440, 2015 | 58 | 2015 |
| Inhibition of human matriptase by eglin c variants A Désilets, JM Longpré, MÈ Beaulieu, R Leduc FEBS letters 580 (9), 2227-2232, 2006 | 57 | 2006 |
| Identification of prodomain determinants involved in ADAMTS-1 biosynthesis JM Longpré, R Leduc Journal of Biological Chemistry 279 (32), 33237-33245, 2004 | 55 | 2004 |
| Mechanistic insights into the role of the chemokine CCL2/CCR2 axis in dorsal root ganglia to peripheral inflammation and pain hypersensitivity MA Dansereau, É Midavaine, V Bégin-Lavallée, M Belkouch, N Beaudet, ... Journal of neuroinflammation 18, 1-18, 2021 | 51 | 2021 |
| Ectodomain shedding of furin: kinetics and role of the cysteine-rich region JB Denault, L Bissonnette, JM Longpré, G Charest, P Lavigne, R Leduc FEBS letters 527 (1-3), 309-314, 2002 | 49 | 2002 |
| Brain irradiation leads to persistent neuroinflammation and long-term neurocognitive dysfunction in a region-specific manner J Constanzo, É Midavaine, J Fouquet, M Lepage, M Descoteaux, K Kirby, ... Progress in Neuro-Psychopharmacology and Biological Psychiatry 102, 109954, 2020 | 41 | 2020 |
| Identification of 1-({[1-(4-Fluorophenyl)-5-(2-methoxyphenyl)-1H-pyrazol-3-yl]carbonyl}amino)cyclohexane Carboxylic Acid as a Selective Nonpeptide Neurotensin … JB Thomas, AM Giddings, RW Wiethe, S Olepu, KR Warner, P Sarret, ... Journal of Medicinal Chemistry 57 (12), 5318-5332, 2014 | 41 | 2014 |
