Efferocytosis produces a prometastatic landscape during postpartum mammary gland involution JC Stanford, C Young, D Hicks, P Owens, A Williams, DB Vaught, ... The Journal of clinical investigation 124 (11), 4737-4752, 2014 | 132 | 2014 |
Rictor/mTORC2 Drives Progression and Therapeutic Resistance of HER2-Amplified Breast Cancers M Morrison Joly, DJ Hicks, B Jones, V Sanchez, MV Estrada, C Young, ... Cancer research 76 (16), 4752-4764, 2016 | 102 | 2016 |
MYC regulates ductal-neuroendocrine lineage plasticity in pancreatic ductal adenocarcinoma associated with poor outcome and chemoresistance AS Farrell, MM Joly, BL Allen-Petersen, PJ Worth, C Lanciault, D Sauer, ... Nature communications 8 (1), 1728, 2017 | 92 | 2017 |
Receptor tyrosine kinase ERBB4 mediates acquired resistance to ERBB2 inhibitors in breast cancer cells K Canfield, J Li, OM Wilkins, MM Morrison, M Ung, W Wells, CR Williams, ... Cell Cycle 14 (4), 648-655, 2015 | 84 | 2015 |
The receptor tyrosine kinase ErbB3 maintains the balance between luminal and basal breast epithelium JM Balko, TW Miller, MM Morrison, K Hutchinson, C Young, C Rinehart, ... Proceedings of the National Academy of Sciences 109 (1), 221-226, 2012 | 82 | 2012 |
Targeting eNOS in pancreatic cancer BL Lampson, SDS Kendall, BB Ancrile, MM Morrison, MJ Shealy, ... Cancer research 72 (17), 4472-4482, 2012 | 75 | 2012 |
Selective mTORC2 inhibitor therapeutically blocks breast cancer cell growth and survival TA Werfel, S Wang, MA Jackson, TE Kavanaugh, MM Joly, LH Lee, ... Cancer research 78 (7), 1845-1858, 2018 | 74 | 2018 |
Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis M Morrison Joly, MM Williams, DJ Hicks, B Jones, V Sanchez, CD Young, ... Breast Cancer Research 19, 1-15, 2017 | 73 | 2017 |
ErbB3 downregulation enhances luminal breast tumor response to antiestrogens RSC MM Morrison, K Hutchinson, MM Williams, JC The Journal of Clinical Investigation, 2013 | 64 | 2013 |
mTOR directs breast morphogenesis through the PKC-alpha-Rac1 signaling axis MM Morrison, CD Young, S Wang, T Sobolik, VM Sanchez, DJ Hicks, ... PLoS genetics 11 (7), e1005291, 2015 | 53 | 2015 |
Using what we already have: uncovering new drug repurposing strategies in existing omics data JM Pulley, JP Rhoads, RN Jerome, AP Challa, KB Erreger, MM Joly, ... Annual review of pharmacology and toxicology 60, 333-352, 2020 | 52 | 2020 |
Key survival factor, Mcl-1, correlates with sensitivity to combined Bcl-2/Bcl-xL blockade MM Williams, L Lee, DJ Hicks, MM Joly, D Elion, B Rahman, C McKernan, ... Molecular Cancer Research 15 (3), 259-268, 2017 | 48 | 2017 |
Activating PIK3CA mutations induce an epidermal growth factor receptor (EGFR)/extracellular signal-regulated kinase (ERK) paracrine signaling axis in basal-like breast cancer CD Young, LJ Zimmerman, D Hoshino, L Formisano, AB Hanker, ... Molecular & cellular proteomics 14 (7), 1959-1976, 2015 | 46* | 2015 |
ErbB3 drives mammary epithelial survival and differentiation during pregnancy and lactation MM Williams, DB Vaught, MM Joly, DJ Hicks, V Sanchez, P Owens, ... Breast Cancer Research 19, 1-14, 2017 | 28 | 2017 |
Intrinsic apoptotic pathway activation increases response to anti-estrogens in luminal breast cancers MM Williams, L Lee, T Werfel, MMM Joly, DJ Hicks, B Rahman, D Elion, ... Cell Death & Disease 9 (2), 21, 2018 | 24 | 2018 |
Decreased LRIG1 in fulvestrant-treated luminal breast cancer cells permits ErbB3 upregulation and increased growth MM Morrison, MM Williams, DB Vaught, D Hicks, J Lim, C McKernan, ... Oncogene 35 (9), 1143-1152, 2016 | 22 | 2016 |
Renin-angiotensin system modulation with synthetic angiotensin (1-7) and angiotensin II type 1 receptor–biased ligand in adults with COVID-19: two randomized clinical trials WH Self, MS Shotwell, KW Gibbs, M De Wit, DC Files, M Harkins, ... Jama 329 (14), 1170-1182, 2023 | 15 | 2023 |
Repurposing of a thromboxane receptor inhibitor based on a novel role in metastasis identified by phenome-wide association study TA Werfel, DJ Hicks, B Rahman, WE Bendeman, MT Duvernay, JG Maeng, ... Molecular cancer therapeutics 19 (12), 2454-2464, 2020 | 14 | 2020 |
Leveraging human genetics to identify safety signals prior to drug marketing approval and clinical use RN Jerome, MM Joly, N Kennedy, JK Shirey-Rice, DM Roden, ... Drug safety 43, 567-582, 2020 | 11 | 2020 |
Evaluating automated electronic case report form data entry from electronic health records AC Cheng, MK Banasiewicz, JD Johnson, L Sulieman, N Kennedy, ... Journal of Clinical and Translational Science 7 (1), e29, 2023 | 9 | 2023 |