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Thomas C T Michaels
Thomas C T Michaels
Assistant Professor University College London
Email verificata su cam.ac.uk
Titolo
Citata da
Citata da
Anno
Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation
C Galvagnion, AK Buell, G Meisl, TCT Michaels, M Vendruscolo, ...
Nature chemical biology 11 (3), 229-234, 2015
4582015
Molecular mechanisms of protein aggregation from global fitting of kinetic models
G Meisl, JB Kirkegaard, P Arosio, TCT Michaels, M Vendruscolo, ...
Nature protocols 11 (2), 252-272, 2016
4142016
Secondary nucleation in amyloid formation
M Törnquist, TCT Michaels, K Sanagavarapu, X Yang, G Meisl, ...
Chemical Communications 54 (63), 8667-8684, 2018
2102018
Kinetic analysis reveals the diversity of microscopic mechanisms through which molecular chaperones suppress amyloid formation
P Arosio, TCT Michaels, S Linse, C Månsson, C Emanuelsson, J Presto, ...
Nature communications 7 (1), 1-9, 2016
1802016
Cholesterol catalyses Aβ42 aggregation through a heterogeneous nucleation pathway in the presence of lipid membranes
J Habchi, S Chia, C Galvagnion, TCT Michaels, MMJ Bellaiche, ...
Nature chemistry 10 (6), 673-683, 2018
1502018
Dynamics of oligomer populations formed during the aggregation of Alzheimer’s Aβ42 peptide
TCT Michaels, A Šarić, S Curk, K Bernfur, P Arosio, G Meisl, AJ Dear, ...
Nature chemistry 12 (5), 445-451, 2020
1262020
Chemical kinetics for bridging molecular mechanisms and macroscopic measurements of amyloid fibril formation
TCT Michaels, A Šarić, J Habchi, S Chia, G Meisl, M Vendruscolo, ...
Annual review of physical chemistry 69, 273-298, 2018
1172018
Distinct thermodynamic signatures of oligomer generation in the aggregation of the amyloid-β peptide
SIA Cohen, R Cukalevski, TCT Michaels, A Šarić, M Törnquist, ...
Nature chemistry 10 (5), 523-531, 2018
1052018
Fabrication of fibrillosomes from droplets stabilized by protein nanofibrils at all-aqueous interfaces
Y Song, U Shimanovich, TCT Michaels, Q Ma, J Li, TPJ Knowles, ...
Nature Communications 7 (1), 1-8, 2016
1002016
Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes
R Limbocker, S Chia, FS Ruggeri, M Perni, R Cascella, GT Heller, G Meisl, ...
Nature communications 10 (1), 1-13, 2019
932019
Physical determinants of the self-replication of protein fibrils
A Šarić, AK Buell, G Meisl, TCT Michaels, CM Dobson, S Linse, ...
Nature physics 12 (9), 874-880, 2016
812016
Controlling the physical dimensions of peptide nanotubes by supramolecular polymer coassembly
L Adler-Abramovich, P Marco, ZA Arnon, RCG Creasey, TCT Michaels, ...
ACS nano 10 (8), 7436-7442, 2016
762016
Dynamic microfluidic control of supramolecular peptide self-assembly
ZA Arnon, A Vitalis, A Levin, TCT Michaels, A Caflisch, TPJ Knowles, ...
Nature communications 7 (1), 1-7, 2016
752016
β-Synuclein suppresses both the initiation and amplification steps of α-synuclein aggregation via competitive binding to surfaces
JWP Brown, AK Buell, TCT Michaels, G Meisl, J Carozza, P Flagmeier, ...
Scientific reports 6 (1), 1-10, 2016
702016
Budding-like division of all-aqueous emulsion droplets modulated by networks of protein nanofibrils
Y Song, TCT Michaels, Q Ma, Z Liu, H Yuan, S Takayama, TPJ Knowles, ...
Nature communications 9 (1), 1-7, 2018
612018
Measurement of tau filament fragmentation provides insights into prion-like spreading
F Kundel, L Hong, B Falcon, WA McEwan, TCT Michaels, G Meisl, ...
ACS chemical neuroscience 9 (6), 1276-1282, 2018
612018
Kinetic diversity of amyloid oligomers
AJ Dear, TCT Michaels, G Meisl, D Klenerman, S Wu, S Perrett, S Linse, ...
Proceedings of the National Academy of Sciences 117 (22), 12087-12094, 2020
572020
Kinetics of spontaneous filament nucleation via oligomers: Insights from theory and simulation
A Šarić, TCT Michaels, A Zaccone, TPJ Knowles, D Frenkel
The Journal of Chemical Physics 145 (21), 211926, 2016
562016
Quantitative analysis of co-oligomer formation by amyloid-beta peptide isoforms
M Iljina, GA Garcia, AJ Dear, J Flint, P Narayan, TCT Michaels, ...
Scientific reports 6 (1), 1-8, 2016
492016
Dynamics of protein aggregation and oligomer formation governed by secondary nucleation
TCT Michaels, HW Lazell, P Arosio, TPJ Knowles
The Journal of chemical physics 143 (5), 08B602_1, 2015
452015
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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