Thomas C T Michaels
Thomas C T Michaels
University of Cambridge and Harvard University
Email verificata su
Citata da
Citata da
Lipid vesicles trigger α-synuclein aggregation by stimulating primary nucleation
C Galvagnion, AK Buell, G Meisl, TCT Michaels, M Vendruscolo, ...
Nature chemical biology 11 (3), 229-234, 2015
Molecular mechanisms of protein aggregation from global fitting of kinetic models
G Meisl, JB Kirkegaard, P Arosio, TCT Michaels, M Vendruscolo, ...
Nature protocols 11 (2), 252-272, 2016
Kinetic analysis reveals the diversity of microscopic mechanisms through which molecular chaperones suppress amyloid formation
P Arosio, TCT Michaels, S Linse, C Månsson, C Emanuelsson, J Presto, ...
Nature communications 7 (1), 1-9, 2016
Secondary nucleation in amyloid formation
M Törnquist, TCT Michaels, K Sanagavarapu, X Yang, G Meisl, ...
Chemical Communications 54 (63), 8667-8684, 2018
Cholesterol catalyses Aβ42 aggregation through a heterogeneous nucleation pathway in the presence of lipid membranes
J Habchi, S Chia, C Galvagnion, TCT Michaels, MMJ Bellaiche, ...
Nature chemistry 10 (6), 673-683, 2018
Chemical kinetics for bridging molecular mechanisms and macroscopic measurements of amyloid fibril formation
TCT Michaels, A Šarić, J Habchi, S Chia, G Meisl, M Vendruscolo, ...
Annual review of physical chemistry 69, 273-298, 2018
Fabrication of fibrillosomes from droplets stabilized by protein nanofibrils at all-aqueous interfaces
Y Song, U Shimanovich, TCT Michaels, Q Ma, J Li, TPJ Knowles, ...
Nature communications 7 (1), 1-8, 2016
Physical determinants of the self-replication of protein fibrils
A Šarić, AK Buell, G Meisl, TCT Michaels, CM Dobson, S Linse, ...
Nature physics 12 (9), 874-880, 2016
Distinct thermodynamic signatures of oligomer generation in the aggregation of the amyloid-β peptide
SIA Cohen, R Cukalevski, TCT Michaels, A Šarić, M Törnquist, ...
Nature chemistry 10 (5), 523-531, 2018
Dynamic microfluidic control of supramolecular peptide self-assembly
ZA Arnon, A Vitalis, A Levin, TCT Michaels, A Caflisch, TPJ Knowles, ...
Nature communications 7 (1), 1-7, 2016
Dynamics of oligomer populations formed during the aggregation of Alzheimer’s Aβ42 peptide
TCT Michaels, A Šarić, S Curk, K Bernfur, P Arosio, G Meisl, AJ Dear, ...
Nature chemistry 12 (5), 445-451, 2020
Trodusquemine enhances Aβ 42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes
R Limbocker, S Chia, FS Ruggeri, M Perni, R Cascella, GT Heller, G Meisl, ...
Nature communications 10 (1), 1-13, 2019
Controlling the physical dimensions of peptide nanotubes by supramolecular polymer coassembly
L Adler-Abramovich, P Marco, ZA Arnon, RCG Creasey, TCT Michaels, ...
ACS nano 10 (8), 7436-7442, 2016
β-Synuclein suppresses both the initiation and amplification steps of α-synuclein aggregation via competitive binding to surfaces
JWP Brown, AK Buell, TCT Michaels, G Meisl, J Carozza, P Flagmeier, ...
Scientific reports 6 (1), 1-10, 2016
Budding-like division of all-aqueous emulsion droplets modulated by networks of protein nanofibrils
Y Song, TCT Michaels, Q Ma, Z Liu, H Yuan, S Takayama, TPJ Knowles, ...
Nature communications 9 (1), 1-7, 2018
Measurement of tau filament fragmentation provides insights into prion-like spreading
F Kundel, L Hong, B Falcon, WA McEwan, TCT Michaels, G Meisl, ...
ACS chemical neuroscience 9 (6), 1276-1282, 2018
Kinetics of spontaneous filament nucleation via oligomers: Insights from theory and simulation
A Šarić, TCT Michaels, A Zaccone, TPJ Knowles, D Frenkel
The Journal of chemical physics 145 (21), 211926, 2016
Quantitative analysis of co-oligomer formation by amyloid-beta peptide isoforms
M Iljina, GA Garcia, AJ Dear, J Flint, P Narayan, TCT Michaels, ...
Scientific reports 6 (1), 1-8, 2016
Dynamics of protein aggregation and oligomer formation governed by secondary nucleation
TCT Michaels, HW Lazell, P Arosio, TPJ Knowles
The Journal of chemical physics 143 (5), 08B602_1, 2015
Role of filament annealing in the kinetics and thermodynamics of nucleated polymerization
TCT Michaels, TPJ Knowles
The Journal of chemical physics 140 (21), 214904, 2014
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
Articoli 1–20