Chemical properties of lipids strongly affect the kinetics of the membrane-induced aggregation of α-synuclein C Galvagnion, JWP Brown, MM Ouberai, P Flagmeier, M Vendruscolo, ... Proceedings of the National Academy of Sciences 113 (26), 7065-7070, 2016 | 302 | 2016 |
The small heat shock protein Hsp27 binds α-synuclein fibrils, preventing elongation and cytotoxicity D Cox, DR Whiten, JWP Brown, MH Horrocks, R San Gil, CM Dobson, ... Journal of Biological Chemistry 293 (12), 4486-4497, 2018 | 114 | 2018 |
β-Synuclein suppresses both the initiation and amplification steps of α-synuclein aggregation via competitive binding to surfaces JWP Brown, AK Buell, TCT Michaels, G Meisl, J Carozza, P Flagmeier, ... Scientific reports 6 (1), 36010, 2016 | 94 | 2016 |
Viral M45 and necroptosis‐associated proteins form heteromeric amyloid assemblies CLL Pham, N Shanmugam, M Strange, A O'Carroll, JWP Brown, ... EMBO reports 20 (2), e46518, 2019 | 82 | 2019 |
Single-molecule detection on a portable 3D-printed microscope JWP Brown, A Bauer, ME Polinkovsky, A Bhumkar, DJB Hunter, K Gaus, ... Nature Communications 10 (1), 5662, 2019 | 43 | 2019 |
Kinetic barriers to α-synuclein protofilament formation and conversion into mature fibrils JWP Brown, G Meisl, TPJ Knowles, AK Buell, CM Dobson, C Galvagnion Chemical communications 54 (56), 7854-7857, 2018 | 32 | 2018 |
Pathological mutations differentially affect the self-assembly and polymerisation of the innate immune system signalling adaptor molecule MyD88 A O’Carroll, B Chauvin, JWP Brown, A Meagher, J Coyle, J Schill, ... BMC biology 16, 1-16, 2018 | 27 | 2018 |
Rapid exchange of stably bound protein and DNA cargo on a DNA origami receptor JWP Brown, RG Alford, JC Walsh, RE Spinney, SY Xu, S Hertel, ... ACS nano 16 (4), 6455-6467, 2022 | 9 | 2022 |
A sticky situation: Aberrant protein–protein interactions in Parkinson’s disease J Brown, MH Horrocks Seminars in cell & developmental biology 99, 65-77, 2020 | 9 | 2020 |
Metallurgical Processing of PolyMet Mining's NorthMet Deposit for Recovery of Cu—Ni—Co—Zn—Pd—Pt—Au D Dreisinger, W Murray, D Hunter, K Baxter, M Wardell-Johnson, ... Proceedings of the ALTA World Forum on Nickel and Cobalt Hydrometallurgy …, 2005 | 6 | 2005 |
Passage through the expressive student subculture: the initiation and cessation of marijuana use JW Brown University of Southern California, 1971 | 3 | 1971 |
The N-end rule pathway regulates ER stress-induced clusterin release to the cytosol where it directs misfolded proteins for degradation S Satapathy, H Walker, J Brown, Y Gambin, MR Wilson Cell Reports 42 (9), 2023 | | 2023 |
Competing Interactions between Viral RHIM Amyloid-forming Proteins and Host Functional Amyloid Structures Modulate the Cellular Response to Infection M Sunde, CLL Pham, N Shanmugam, MODG Baker, M Steain, A O'Carroll, ... Biophysical Journal 118 (3), 180a-181a, 2020 | | 2020 |
MODULATION OF INTERACTOME BY PROTEIN SELF-ASSEMBLY: THE CASE OF ALPHA-SYNUCLEIN E Sierecki, A Leitao, J Brown, A Chappard, Y Gambin PROTEIN SCIENCE 28, 132-132, 2019 | | 2019 |
The Shifting Interactome of Alpha-Synuclein along its Aggregation Pathway E Sierecki, J Brown, A Leitao, A Chappard, Y Gambin PROTEIN SCIENCE 27, 73-73, 2018 | | 2018 |
Effects of Pathological Mutations on the Prion-Like Polymerisation of MyD88 A O’Carroll, B Chauvin, J Brown, A Meagher, J Coyle, D Hunter, ... bioRxiv, 351726, 2018 | | 2018 |
The small heat shock protein Hsp27 binds-synuclein fibrils, preventing elongation and cytotoxicity D Cox, DR Whiten, J Brown, MH Horrocks, R San Gil, CM Dobson, ... | | |
Supplementary Information: β-Synuclein suppresses both the initiation and amplification steps of α-synuclein aggregation via competitive binding to surfaces JWP Brown, AK Buell, TCT Michaels, G Meisl, J Carozza, P Flagmeier, ... | | |
Supporting Information: Chemical properties of lipids strongly affect the kinetics of the membrane-induced aggregation of α-synuclein C Galvagnion, JWP Brown, MM Ouberai, P Flagmeier, M Vendruscolo, ... | | |