TSPO Ligands Boost Mitochondrial Function and Pregnenolone Synthesis I Lejri, A Grimm, F Hallé, M Abarghaz, C Klein, M Maitre, M Schmitt, ... Journal of Alzheimer's Disease, 1-14, 2019 | 52 | 2019 |
The translocator protein ligand XBD173 improves clinical symptoms and neuropathological markers in the SJL/J mouse model of multiple sclerosis G Leva, C Klein, J Benyounes, F Hallé, F Bihel, N Collongues, J De Seze, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1863 (12 …, 2017 | 36 | 2017 |
Human erythrocytes release ATP by a novel pathway involving VDAC oligomerization independent of pannexin-1 I Marginedas-Freixa, CL Alvarez, M Moras, MF Leal Denis, C Hattab, ... Scientific reports 8 (1), 11384, 2018 | 35 | 2018 |
Emissive Synthetic Cofactors: Enzymatic Interconversions of tzA Analogues of ATP, NAD+, NADH, NADP+, and NADPH F Hallé, A Fin, AR Rovira, Y Tor Angewandte Chemie International Edition 57 (4), 1087-1090, 2018 | 31 | 2018 |
Mitochondria modulatory effects of new TSPO ligands in a cellular model of tauopathies A Grimm, I Lejri, F Hallé, M Schmitt, J Götz, F Bihel, A Eckert Journal of neuroendocrinology 32 (1), e12796, 2020 | 30 | 2020 |
TSPO ligands stimulate ZnPPIX transport and ROS accumulation leading to the inhibition of P. falciparum growth in human blood I Marginedas-Freixa, C Hattab, G Bouyer, F Halle, A Chene, SD Lefevre, ... Scientific reports 6 (1), 33516, 2016 | 18 | 2016 |
Discovery of imidazoquinazolinone derivatives as TSPO ligands modulating neurosteroidogenesis and cellular bioenergetics in neuroblastoma cells expressing amyloid precursor protein F Hallé, I Lejri, M Abarghaz, A Grimm, C Klein, M Maitre, M Schmitt, ... ChemistrySelect 2 (22), 6452-6457, 2017 | 9 | 2017 |
χ-Space Screening of Dermorphin-Based Tetrapeptides through Use of Constrained Arylazepinone and Quinolinone Scaffolds O Van der Poorten, R Van Den Hauwe, E Eiselt, C Betti, K Guillemyn, ... ACS Medicinal Chemistry Letters 8 (11), 1177-1182, 2017 | 6 | 2017 |
Pharmacomodulation of a ligand targeting the HBV capsid hydrophobic pocket M Briday, F Hallé, L Lecoq, S Radix, J Martin, R Montserret, M Dujardin, ... Chemical Science 13 (30), 8840-8847, 2022 | 3 | 2022 |
Crystal structure and identification of a pyrimido[6,1-b][1,3]oxazin-6-one derivative from the reaction of acrolein with 5-(phenoxymethyl)-2-amino-2-oxazoline J Guillon, S Rubio, S Savrimoutou, F Hallé, S Moreau, P Sonnet, ... Comptes Rendus. Chimie 21 (11), 987-992, 2018 | 3 | 2018 |
Synthesis of 3-amino-3,4-dihydro-1H-quinolin-2-ones through regioselective palladium-catalyzed intramolecular cyclization F Hallé, O Van der Poorten, C Doebelin, M Niederst, S Schneider, ... Tetrahedron Letters 57 (14), 1547-1550, 2016 | 3 | 2016 |
A Journey through Hemetsberger–Knittel, Leimgruber–Batcho and Bartoli Reactions: Access to Several Hydroxy 5‐ and 6‐Azaindoles S Radix, F Hallé, Z Mahiout, A Teissonnière, G Bouchez, L Auberger, ... Helvetica Chimica Acta 105 (3), e202100211, 2022 | 1 | 2022 |
Conception, développement et synthèse de ligands du TSPO dans le but de traiter les maladies neurodégénératives F Hallé Université de Strasbourg, 2015 | 1 | 2015 |
Synthesis and Evaluation of New 6-formyl-oxazolo [3, 2-a] pyrimidine derivatives as Potential Src Kinase Inhibitors J Guillon, F Hallé, S Savrimoutou, S Moreau, DH Caignard, P Sonnet 4th International Electronic Conference on Medicinal Chemistry, 5566, 2018 | | 2018 |
Development of imidazo [1, 2-c] quinazolin-5-ones as neuroprotective agents through 18kDa translocator protein (TSPO) activation F Halle, I Lejri, C Klein, M Schmitt, A Eckert, G Mensah, JJ Bourguignon, ... ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 251, 2016 | | 2016 |
L'avenir des ligands du TSPO 18KDA dans le traitement des affections neurologiques F Hallé | | 2014 |