TOP1 inhibition therapy protects against SARS-CoV-2-induced lethal inflammation JSY Ho, BWY Mok, L Campisi, T Jordan, S Yildiz, S Parameswaran, ... Cell 184 (10), 2618-2632. e17, 2021 | 83 | 2021 |
Sequence Specific Modeling of E. coli Cell-Free Protein Synthesis M Vilkhovoy, N Horvath, CH Shih, JA Wayman, K Calhoun, J Swartz, ... ACS synthetic biology 7 (8), 1844-1857, 2018 | 46 | 2018 |
Toward a genome scale sequence specific dynamic model of cell-free protein synthesis in Escherichia coli N Horvath, M Vilkhovoy, JA Wayman, K Calhoun, J Swartz, JD Varner Metabolic engineering communications 10, e00113, 2020 | 43 | 2020 |
Dynamic modeling of cell-free biochemical networks using effective kinetic models JA Wayman, A Sagar, JD Varner Processes 3 (1), 138-160, 2015 | 25 | 2015 |
Improving designer glycan production in Escherichia coli through model-guided metabolic engineering JA Wayman, C Glasscock, TJ Mansell, MP DeLisa, JD Varner Metabolic Engineering Communications 9, e00088, 2019 | 24 | 2019 |
Biological systems modeling of metabolic and signaling networks JA Wayman, JD Varner Current Opinion in Chemical Engineering 2 (4), 365-372, 2013 | 16 | 2013 |
Inflammatory blockade prevents injury to the developing pulmonary gas exchange surface in preterm primates A Toth, S Steinmeyer, P Kannan, J Gray, CM Jackson, S Mukherjee, ... Science Translational Medicine 14 (638), eabl8574, 2022 | 15 | 2022 |
maxATAC: Genome-scale transcription-factor binding prediction from ATAC-seq with deep neural networks TA Cazares, FW Rizvi, B Iyer, X Chen, M Kotliar, AT Bejjani, JA Wayman, ... PLOS Computational Biology 19 (1), e1010863, 2023 | 11 | 2023 |
Topoisomerase 1 inhibition therapy protects against SARS-CoV-2-induced inflammation and death in animal models JS Yuin Ho, B Wing-Yee Mok, L Campisi, T Jordan, S Yildiz, ... bioRxiv, 2020.12. 01.404483, 2020 | 8 | 2020 |
An atlas of gene regulatory networks for memory CD4+ T cells in youth and old age JA Wayman, A Thomas, A Bejjani, A Katko, M Almanan, A Godarova, ... bioRxiv, 2023.03. 07.531590, 2023 | 4 | 2023 |
Elevated CD153 Expression on Aged T Follicular Helper Cells is Vital for B cell Responses AL Thomas, JA Wayman, M Almanan, AT Bejjani, ER Miraldi, ... bioRxiv, 2023 | 2 | 2023 |
Alveolar epithelial progenitor cells drive lung regeneration via dynamic changes in chromatin topology modulated by lineage-specific Nkx2-1 activity A Toth, P Kannan, J Snowball, JM Kofron, JA Wayman, JP Bridges, ... bioRxiv, 2022.08. 30.505919, 2022 | 2 | 2022 |
Alveolar epithelial progenitor cells require Nkx2-1 to maintain progenitor-specific epigenomic state during lung homeostasis and regeneration A Toth, P Kannan, J Snowball, M Kofron, JA Wayman, JP Bridges, ... Nature Communications 14 (1), 8452, 2023 | 1 | 2023 |
High-resolution promoter interaction analysis in Type 3 Innate Lymphoid Cells implicates Batten Disease gene CLN3 in Crohn’s Disease aetiology V Malysheva, H Ray-Jones, TA Cazares, O Clay, D Ohayon, P Artemov, ... bioRxiv, 2022.10. 19.512842, 2022 | 1 | 2022 |
Accessible chromatin maps of inflammatory bowel disease intestine nominate cell-type mediators of genetic disease risk JA Wayman, Z Yang, E Angerman, E Bonkowski, I Jurickova, X Chen, ... bioRxiv, 2024.02. 09.579678, 2024 | | 2024 |
Accumulation of immune-suppressive CD4+ T cells in aging–tempering inflammaging at the expense of immunity AL Thomas, A Godarova, JA Wayman, ER Miraldi, DA Hildeman, ... Seminars in Immunology 70, 101836, 2023 | | 2023 |
IDENTIFYING PATHOGENIC CELL POPULATIONS WITH GENETIC VARIANT PREDISPOSITION IN PRIMARY SCLEROSING CHOLANGITIS THROUGH SINGLE-CELL MULTIOME PROFILING Z Yang, R Kudira, J Wayman, X Chen, A Bejjani, L Kottyan, M Weirauch, ... HEPATOLOGY 78, S2013-S2014, 2023 | | 2023 |
AMPHIREGULIN MEDIATES TREG-PROTECTION OF CHOLANGIOCYTES FROM IMMUNE MEDIATED INJURY AND ITS HEPATIC EXPRESSION IS ASSOCIATED WITH CLINICAL OUTCOME IN BILIARY ATRESIA R Kudira, L Pfuhler, J Wayman, Z Yang, I Osuji, S Dong, R Karns, ... HEPATOLOGY 74, 145A-146A, 2021 | | 2021 |
DISCOVERY OF THE CELL-CELL COMMUNICATION AND GENE REGULATORY NETWORKS DRIVING TOXIC BILE INDUCED BILIARY EPITHELIAL INJURY, REPAIR, AND LIVER FIBROSIS Z Yang, J Wayman, R Kudira, P Bariya, L Pfuhler, R Herro, K Roskin, ... HEPATOLOGY 74, 114A-115A, 2021 | | 2021 |
HEPATIC LYMPHOCYTE RESPONSES DRIVE HEPATIC FIBROSIS IN A NOVEL MODEL OF AUTOIMMUNE LIVER DISEASE FOLLOWING TOXIC BILE INJURY R Kudira, L Pfuhler, J Wayman, Z Yang, M Mullen, P Bariya, R Herro, ... HEPATOLOGY 74, 269A-270A, 2021 | | 2021 |