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Andrea Locci
Andrea Locci
Senior Scientist, Abbott Laboratories
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Neurosteroid biosynthesis down‐regulation and changes in GABAA receptor subunit composition: a biomarker axis in stress‐induced cognitive and emotional …
A Locci, G Pinna
British journal of pharmacology 174 (19), 3226-3241, 2017
1242017
Neuroactive steroids and PTSD treatment
AM Rasmusson, CE Marx, SL Pineles, A Locci, ER Scioli-Salter, YI Nillni, ...
Neuroscience letters 649, 156-163, 2017
932017
Decreased allopregnanolone induced by hormonal contraceptives is associated with a reduction in social behavior and sexual motivation in female rats
F Santoru, R Berretti, A Locci, P Porcu, A Concas
Psychopharmacology 231, 3351-3364, 2014
692014
Stimulation of Peroxisome Proliferator-Activated Receptor-α by N-Palmitoylethanolamine Engages Allopregnanolone Biosynthesis to Modulate Emotional Behavior
A Locci, G Pinna
Biological psychiatry 85 (12), 1036-1045, 2019
652019
Comparison of memory, affective behavior, and neuropathology in APPNLGF knock-in mice to 5xFAD and APP/PS1 mice
A Locci, H Orellana, G Rodriguez, M Gottliebson, B McClarty, ...
Behavioural brain research 404, 113192, 2021
452021
Social isolation in early versus late adolescent mice is associated with persistent behavioral deficits that can be improved by neurosteroid-based treatment
A Locci, P Geoffroy, M Miesch, AG Mensah-Nyagan, G Pinna
Frontiers in Cellular Neuroscience 11, 208, 2017
452017
Social isolation as a promising animal model of PTSD comorbid suicide: neurosteroids and cannabinoids as possible treatment options
A Locci, G Pinna
Progress in neuro-psychopharmacology and biological psychiatry 92, 243-259, 2019
342019
Neonatal exposure to estradiol decreases hypothalamic allopregnanolone concentrations and alters agonistic and sexual but not affective behavior in adult female rats
R Berretti, F Santoru, A Locci, C Sogliano, A Calza, E Choleris, P Porcu, ...
Hormones and behavior 65 (2), 142-153, 2014
222014
Neonatal estradiol exposure to female rats changes GABAA receptor expression and function, and spatial learning during adulthood
A Locci, P Porcu, G Talani, F Santoru, R Berretti, E Giunti, V Licheri, ...
Hormones and behavior 87, 35-46, 2017
182017
Failure of Acute Ethanol Administration to Alter Cerebrocortical and Hippocampal Allopregnanolone Levels in C 57 BL/6 J and DBA/2 J Mice
P Porcu, A Locci, F Santoru, R Berretti, AL Morrow, A Concas
Alcoholism: Clinical and Experimental Research 38 (4), 948-958, 2014
152014
Sex differences in CRF1, CRF, and CRFBP expression in C57BL/6J mouse brain across the lifespan and in response to acute stress
A Locci, Y Yan, G Rodriguez, H Dong
Journal of Neurochemistry, 2020
112020
Changes in stress-stimulated allopregnanolone levels induced by neonatal estradiol treatment are associated with enhanced dopamine release in adult female rats: reversal by …
P Porcu, V Lallai, A Locci, S Catzeddu, V Serra, MG Pisu, M Serra, ...
Psychopharmacology 234, 749-760, 2017
102017
Preliminary evidence of a predictive clinical biomarker in pcdh19-related epilepsy: significant treatment effect of ganaxolone in biomarker-positive patients
J Sullivan, N Specchio, M Chez, G Pinna, A Locci, R Jarrar, A Poduri, ...
Annual meeting abstracts [Internet]. American Epilepsy Society, 2018
82018
Immunochemical Localization of GABAA Receptor Subunits in the Freshwater Polyp Hydra vulgaris (Cnidaria, Hydrozoa)
A Concas, R Imperatore, F Santoru, A Locci, P Porcu, L Cristino, ...
Neurochemical research 41, 2914-2922, 2016
72016
Sex-dependent sensitivity to positive allosteric modulation of GABA action in an APP knock-in mouse model of Alzheimer's disease: potential epigenetic regulation
J Auta, A Locci, A Guidotti, JM Davis, H Dong
Current Research in Neurobiology 3, 100025, 2022
62022
Neurosteroid-based biomarkers and therapeutic approaches to facilitate resilience after trauma
A Locci, F Khan, MA Khan, G Pinna
Facilitating Resilience after PTSD: A Translational Approach, 199-235, 2018
62018
Characterization of apathy-like behaviors in the 5xFAD mouse model of Alzheimer’s disease
R Keszycki, G Rodriguez, JT Dunn, A Locci, H Orellana, I Haupfear, ...
Neurobiology of Aging 126, 113-122, 2023
52023
Stimulation of PPAR-α by N-palmitoylethanolamine engages allopregnanolone biosynthesis to modulate emotional behavior
A Locci, G Pinna
Biol Psychiatr 85, 1036-45, 2019
42019
Stimulation of the endocannabinoid system by PEA engages neurosteroid biosynthesis to improve anxiety and fear in a PTSD mouse model
A Locci, G Pinna
Soc. Neurosci. Abstr 13420, 2017
32017
Characterization and comparison of memory and affective behavior in common transgenic mouse models of Alzheimer’s disease
H Dong, A Locci, RM Keszycki, HD Orellana, G Rodriguez, DW Fisher
2020 Alzheimer's Association International Conference, 2020
1*2020
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