| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 10693 | 2021 |
| Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies MA Nalls, C Blauwendraat, CL Vallerga, K Heilbron, S Bandres-Ciga, ... The Lancet Neurology 18 (12), 1091-1102, 2019 | 1538 | 2019 |
| Intraneuronal Aβ, non-amyloid aggregates and neurodegeneration in a Drosophila model of Alzheimer’s disease DC Crowther, KJ Kinghorn, E Miranda, R Page, JA Curry, FAI Duthie, ... Neuroscience 132 (1), 123-135, 2005 | 434 | 2005 |
| Loss of PLA2G6 leads to elevated mitochondrial lipid peroxidation and mitochondrial dysfunction KJ Kinghorn, JI Castillo-Quan, F Bartolome, PR Angelova, L Li, S Pope, ... Brain 138 (7), 1801-1816, 2015 | 181 | 2015 |
| Lithium promotes longevity through GSK3/NRF2-dependent hormesis JI Castillo-Quan, L Li, KJ Kinghorn, DK Ivanov, LS Tain, C Slack, F Kerr, ... Cell reports 15 (3), 638-650, 2016 | 180 | 2016 |
| A Drosophila Model of Neuronopathic Gaucher Disease Demonstrates Lysosomal-Autophagic Defects and Altered mTOR Signalling and Is Functionally Rescued … KJ Kinghorn, S Grönke, JI Castillo-Quan, NS Woodling, L Li, E Sirka, ... Journal of Neuroscience 36 (46), 11654-11670, 2016 | 135 | 2016 |
| Misfolded PrP impairs the UPS by interaction with the 20S proteasome and inhibition of substrate entry P Deriziotis, R André, DM Smith, R Goold, KJ Kinghorn, M Kristiansen, ... The EMBO journal 30 (15), 3065-3077, 2011 | 134 | 2011 |
| Identification of candidate Parkinson disease genes by integrating genome-wide association study, expression, and epigenetic data sets DA Kia, D Zhang, S Guelfi, C Manzoni, L Hubbard, RH Reynolds, J Botía, ... JAMA neurology 78 (4), 464-472, 2021 | 116 | 2021 |
| Mitochondria function associated genes contribute to Parkinson’s Disease risk and later age at onset KJ Billingsley, IA Barbosa, S Bandrés-Ciga, JP Quinn, VJ Bubb, ... npj Parkinson's Disease 5 (1), 8, 2019 | 99 | 2019 |
| Neuroserpin binds Aβ and is a neuroprotective component of amyloid plaques in Alzheimer disease KJ Kinghorn, DC Crowther, LK Sharp, C Nerelius, RL Davis, HT Chang, ... Journal of biological chemistry 281 (39), 29268-29277, 2006 | 99 | 2006 |
| Moving beyond neurons: the role of cell type-specific gene regulation in Parkinson’s disease heritability RH Reynolds, J Botía, MA Nalls, J Hardy, SA Gagliano Taliun, M Ryten npj Parkinson's Disease 5 (1), 6, 2019 | 91 | 2019 |
| Practical genetics: alpha-1-antitrypsin deficiency and the serpinopathies DC Crowther, D Belorgey, E Miranda, KJ Kinghorn, LK Sharp, DA Lomas European journal of human genetics 12 (3), 167-172, 2004 | 88 | 2004 |
| A triple drug combination targeting components of the nutrient-sensing network maximizes longevity JI Castillo-Quan, LS Tain, KJ Kinghorn, L Li, S Grönke, Y Hinze, ... Proceedings of the National Academy of Sciences 116 (42), 20817-20819, 2019 | 79 | 2019 |
| The endocytic membrane trafficking pathway plays a major role in the risk of Parkinson's disease S Bandres‐Ciga, S Saez‐Atienzar, L Bonet‐Ponce, K Billingsley, D Vitale, ... Movement Disorders 34 (4), 460-468, 2019 | 78 | 2019 |
| Molecular mousetraps and the serpinopathies DA Lomas, D Belorgey, M Mallya, E Miranda, KJ Kinghorn, LK Sharp, ... Biochemical Society Transactions 33 (2), 321-330, 2005 | 78 | 2005 |
| Shifting equilibriums in Alzheimer’s disease: The complex roles of microglia in neuroinflammation, neuronal survival and neurogenesis SC Gray, KJ Kinghorn, NS Woodling Neural Regeneration Research 15 (7), 1208-1219, 2020 | 68 | 2020 |
| Penetrance of Parkinson's Disease in LRRK2 p.G2019S Carriers Is Modified by a Polygenic Risk Score H Iwaki, C Blauwendraat, MB Makarious, S Bandrés‐Ciga, HL Leonard, ... Movement Disorders 35 (5), 774-780, 2020 | 61 | 2020 |
| The emerging role of autophagic-lysosomal dysfunction in Gaucher disease and Parkinson's disease KJ Kinghorn, AM Asghari, JI Castillo-Quan Neural regeneration research 12 (3), 380-384, 2017 | 55 | 2017 |
| The genetic architecture of Parkinson disease in Spain: characterizing population‐specific risk, differential haplotype structures, and providing etiologic insight S Bandres‐Ciga, S Ahmed, MS Sabir, C Blauwendraat, ... Movement Disorders 34 (12), 1851-1863, 2019 | 54 | 2019 |
| Fine-tuning autophagy maximises lifespan and is associated with changes in mitochondrial gene expression in Drosophila I Bjedov, HM Cochemé, A Foley, D Wieser, NS Woodling, JI Castillo-Quan, ... PLoS genetics 16 (11), e1009083, 2020 | 51 | 2020 |
