Jeffrey Nye
Jeffrey Nye
Johnson & Johnson Innovation, Janssen R&D, LLC
Verified email at - Homepage
Cited by
Cited by
aph-1 and pen-2 are required for Notch pathway signaling, γ-secretase cleavage of βAPP, and presenilin protein accumulation
R Francis, G McGrath, J Zhang, DA Ruddy, M Sym, J Apfeld, M Nicoll, ...
Developmental cell 3 (1), 85-97, 2002
Radial glial identity is promoted by Notch1 signaling in the murine forebrain
N Gaiano, JS Nye, G Fishell
Neuron 26 (2), 395-404, 2000
Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells
S Hitoshi, T Alexson, V Tropepe, D Donoviel, AJ Elia, JS Nye, RA Conlon, ...
Genes & development 16 (7), 846-858, 2002
The intracellular domain of mouse Notch: a constitutively activated repressor of myogenesis directed at the basic helix-loop-helix region of MyoD
R Kopan, JS Nye, H Weintraub
Development 120 (9), 2385-2396, 1994
Signal transduction by activated mNotch: importance of proteolytic processing and its regulation by the extracellular domain.
R Kopan, EH Schroeter, H Weintraub, JS Nye
Proceedings of the National Academy of Sciences 93 (4), 1683-1688, 1996
An activated Notch suppresses neurogenesis and myogenesis but not gliogenesis in mammalian cells
JS Nye, R Kopan, R Axel
Development 120 (9), 2421-2430, 1994
Porphyrins are endogenous ligands for the mitochondrial (peripheral-type) benzodiazepine receptor.
A Verma, JS Nye, SH Snyder
Proceedings of the National Academy of Sciences 84 (8), 2256-2260, 1987
Glycogen synthase kinase-3β modulates notch signaling and stability
DR Foltz, MC Santiago, BE Berechid, JS Nye
Current Biology 12 (12), 1006-1011, 2002
Safety and efficacy of galantamine in subjects with mild cognitive impairment
B Winblad, S Gauthier, L Scinto, H Feldman, GK Wilcock, L Truyen, ...
Neurology 70 (22), 2024-2035, 2008
Drug solubilizers to aid pharmacologists: amorphous cyclodextrin derivatives
J Pitha, T Irie, PB Sklar, JS Nye
Life sciences 43 (6), 493-502, 1988
Spatiotemporal selectivity of response to Notch1 signals in mammalian forebrain precursors
CB Chambers, Y Peng, H Nguyen, N Gaiano, G Fishell, JS Nye
Development 128 (5), 689-702, 2001
Autonomous and non-autonomous regulation of mammalian neurite development by Notch1 and Delta1
JL Franklin, BE Berechid, FB Cutting, A Presente, CB Chambers, DR Foltz, ...
Current Biology 9 (24), 1448-1457, 1999
Human cortical neuronal cell line: establishment from a patient with unilateral megalencephaly
GV Ronnett, LD Hester, JS Nye, K Connors, SH Snyder
Science 248 (4955), 603-605, 1990
Deletion of PBP/PPARBP, the gene for nuclear receptor coactivator peroxisome proliferator-activated receptor-binding protein, results in embryonic lethality
Y Zhu, C Qi, Y Jia, JS Nye, MS Rao, JK Reddy
Journal of Biological Chemistry 275 (20), 14779-14782, 2000
Developmental signalling: vertebrate ligands for Notch
JS Nye, R Kopan
Current Biology 5 (9), 966-969, 1995
Mutant lambda phage repressor with a specific defect in its positive control function.
L Guarente, JS Nye, A Hochschild, M Ptashne
Proceedings of the National Academy of Sciences 79 (7), 2236-2239, 1982
Innovative solutions to novel drug development in mental health
TR Insel, V Voon, JS Nye, VJ Brown, BM Altevogt, ET Bullmore, ...
Neuroscience & Biobehavioral Reviews 37 (10), 2438-2444, 2013
Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis
BTD Tobe, AM Crain, AM Winquist, B Calabrese, H Makihara, W Zhao, ...
Proceedings of the National Academy of Sciences 114 (22), E4462-E4471, 2017
CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice
R Mancuso, G Fryatt, M Cleal, J Obst, E Pipi, J Monzón-Sandoval, E Ribe, ...
Brain 142 (10), 3243-3264, 2019
Genetic studies in neural tube defects
EC Melvin, TM George, G Worley, A Franklin, J Mackey, K Viles, N Shah, ...
Pediatric neurosurgery 32 (1), 1-9, 2000
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