| Introducing protein intrinsic disorder J Habchi, P Tompa, S Longhi, VN Uversky Chemical reviews 114 (13), 6561-6588, 2014 | 599 | 2014 |
| Systematic development of small molecules to inhibit specific microscopic steps of Aβ42 aggregation in Alzheimer’s disease J Habchi, S Chia, R Limbocker, B Mannini, M Ahn, M Perni, O Hansson, ... Proceedings of the National Academy of Sciences 114 (2), E200-E208, 2017 | 172 | 2017 |
| An anticancer drug suppresses the primary nucleation reaction that initiates the production of the toxic Aβ42 aggregates linked with Alzheimer’s disease J Habchi, P Arosio, M Perni, AR Costa, M Yagi-Utsumi, P Joshi, S Chia, ... Science advances 2 (2), e1501244, 2016 | 171 | 2016 |
| Structural disorder in viral proteins B Xue, D Blocquel, J Habchi, AV Uversky, L Kurgan, VN Uversky, ... Chemical reviews 114 (13), 6880-6911, 2014 | 162 | 2014 |
| Cholesterol catalyses Aβ42 aggregation through a heterogeneous nucleation pathway in the presence of lipid membranes J Habchi, S Chia, C Galvagnion, TCT Michaels, MMJ Bellaiche, ... Nature chemistry 10 (6), 673-683, 2018 | 155 | 2018 |
| Chemical kinetics for bridging molecular mechanisms and macroscopic measurements of amyloid fibril formation J Habchi, S Chia, G Meisl, M Vendruscolo, CM Dobson, TPJ Knowles Annual review of physical chemistry 69, 273-98, 2018 | 122 | 2018 |
| The inverted free energy landscape of an intrinsically disordered peptide by simulations and experiments D Granata, F Baftizadeh, J Habchi, C Galvagnion, A De Simone, ... Scientific reports 5 (1), 1-15, 2015 | 97 | 2015 |
| Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes R Limbocker, S Chia, FS Ruggeri, M Perni, R Cascella, GT Heller, G Meisl, ... Nature communications 10 (1), 1-13, 2019 | 94 | 2019 |
| Structural disorder within Henipavirus nucleoprotein and phosphoprotein: from predictions to experimental assessment J Habchi, L Mamelli, H Darbon, S Longhi PLoS One 5 (7), e11684, 2010 | 75 | 2010 |
| AFM-based single molecule techniques: unraveling the amyloid pathogenic species FS Ruggeri, J Habchi, A Cerreta, G Dietler Current pharmaceutical design 22 (26), 3950-3970, 2016 | 73 | 2016 |
| Atomic resolution description of the interaction between the nucleoprotein and phosphoprotein of Hendra virus G Communie, J Habchi, F Yabukarski, D Blocquel, R Schneider, ... PLoS pathogens 9 (9), e1003631, 2013 | 72 | 2013 |
| Structural disorder within paramyxovirus nucleoproteins and phosphoproteins J Habchi, S Longhi Molecular Biosystems 8 (1), 69-81, 2012 | 69 | 2012 |
| Characterization of the interactions between the nucleoprotein and the phosphoprotein of Henipavirus J Habchi, S Blangy, L Mamelli, MR Jensen, M Blackledge, H Darbon, ... Journal of Biological Chemistry 286 (15), 13583-13602, 2011 | 66 | 2011 |
| Molecular basis for structural heterogeneity of an intrinsically disordered protein bound to a partner by combined ESI-IM-MS and modeling A D’Urzo, A Konijnenberg, G Rossetti, J Habchi, J Li, P Carloni, F Sobott, ... Journal of The American Society for Mass Spectrometry 26 (3), 472-481, 2014 | 47 | 2014 |
| Compaction and binding properties of the intrinsically disordered C-terminal domain of Henipavirus nucleoprotein as unveiled by deletion studies D Blocquel, J Habchi, A Gruet, S Blangy, S Longhi Molecular bioSystems 8 (1), 392-410, 2012 | 46 | 2012 |
| Massively parallel C. elegans tracking provides multi-dimensional fingerprints for phenotypic discovery M Perni, PK Challa, JB Kirkegaard, R Limbocker, M Koopman, ... Journal of neuroscience methods 306, 57-67, 2018 | 44 | 2018 |
| SAR by kinetics for drug discovery in protein misfolding diseases S Chia, J Habchi, TCT Michaels, SIA Cohen, S Linse, CM Dobson, ... Proceedings of the National Academy of Sciences 115 (41), 10245-10250, 2018 | 42 | 2018 |
| Plasticity in structural and functional interactions between the phosphoprotein and nucleoprotein of measles virus Y Shu, J Habchi, S Costanzo, A Padilla, J Brunel, D Gerlier, M Oglesbee, ... Journal of Biological Chemistry 287 (15), 11951-11967, 2012 | 40 | 2012 |
| Assessing induced folding within the intrinsically disordered C-terminal domain of the Henipavirus nucleoproteins by site-directed spin labeling EPR spectroscopy M Martinho, J Habchi, Z El Habre, L Nesme, B Guigliarelli, V Belle, ... Journal of Biomolecular Structure and Dynamics 31 (5), 453-471, 2013 | 38 | 2013 |
| A fragment-based method of creating small-molecule libraries to target the aggregation of intrinsically disordered proteins P Joshi, S Chia, J Habchi, TPJ Knowles, CM Dobson, M Vendruscolo ACS combinatorial science 18 (3), 144-153, 2016 | 36 | 2016 |
