May Marsh
May Marsh
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An automated microseed matrix-screening method for protein crystallization
A D'Arcy, F Villard, M Marsh
Acta Crystallographica Section D: Biological Crystallography 63 (4), 550-554, 2007
A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs
AE Prota, K Bargsten, JF Diaz, M Marsh, C Cuevas, M Liniger, C Neuhaus, ...
Proceedings of the National Academy of Sciences 111 (38), 13817-13821, 2014
Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons
T Weinert, N Olieric, R Cheng, S Brünle, D James, D Ozerov, D Gashi, ...
Nature communications 8 (1), 1-11, 2017
Structural basis of microtubule stabilization by laulimalide and peloruside A
AE Prota, K Bargsten, PT Northcote, M Marsh, KH Altmann, JH Miller, ...
Angewandte Chemie International Edition 53 (6), 1621-1625, 2014
Using a fragment‐based approach to target protein–protein interactions
DE Scott, MT Ehebauer, T Pukala, M Marsh, TL Blundell, ...
ChemBioChem 14 (3), 332-342, 2013
Microseed matrix screening for optimization in protein crystallization: what have we learned?
A D'Arcy, T Bergfors, SW Cowan-Jacob, M Marsh
Acta Crystallographica Section F: Structural Biology Communications 70 (9 …, 2014
Targeting protein–protein interactions and fragment-based drug discovery
E Valkov, T Sharpe, M Marsh, S Greive, M Hyvönen
Fragment-Based Drug Discovery and X-Ray Crystallography, 145-179, 2011
Biophysical and computational fragment-based approaches to targeting protein–protein interactions: applications in structure-guided drug discovery
A Winter, AP Higueruelo, M Marsh, A Sigurdardottir, WR Pitt, TL Blundell
Quarterly reviews of biophysics 45 (4), 383-426, 2012
An enantioselective artificial Suzukiase based on the biotin–streptavidin technology
A Chatterjee, H Mallin, J Klehr, J Vallapurackal, AD Finke, L Vera, ...
Chemical science 7 (1), 673-677, 2016
Structural basis for− 10 promoter element melting by environmentally induced sigma factors
S Campagne, ME Marsh, G Capitani, JA Vorholt, FHT Allain
Nature structural & molecular biology 21 (3), 269-276, 2014
Thermodynamic properties of water molecules at a protein–protein interaction surface
DJ Huggins, M Marsh, MC Payne
Journal of chemical theory and computation 7 (11), 3514-3522, 2011
NMR-based determination of the 3D structure of the ligand–protein interaction site without protein resonance assignment
J Orts, MA Wälti, M Marsh, L Vera, AD Gossert, P Güntert, R Riek
Journal of the American Chemical Society 138 (13), 4393-4400, 2016
Structural and Spectroscopic Consequences of Hexacoordination of a Bacteriochlorophyll Cofactor in the Rhodobacter sphaeroides Reaction Center,
D Frolov, M Marsh, LI Crouch, PK Fyfe, B Robert, R van Grondelle, ...
Biochemistry 49 (9), 1882-1892, 2010
Structural insights into plasticity and discovery of remdesivir metabolite GS-441524 binding in SARS-CoV-2 macrodomain
X Ni, M Schröder, V Olieric, ME Sharpe, V Hernandez-Olmos, ...
ACS medicinal chemistry letters 12 (4), 603-609, 2021
Structure of bacterial glutathione-S-transferase maleyl pyruvate isomerase and implications for mechanism of isomerisation
M Marsh, DK Shoemark, A Jacob, C Robinson, B Cahill, NY Zhou, ...
Journal of molecular biology 384 (1), 165-177, 2008
Crystal structures of fungal tectonin in complex with O-methylated glycans suggest key role in innate immune defense
R Sommer, ON Makshakova, T Wohlschlager, S Hutin, M Marsh, A Titz, ...
Structure 26 (3), 391-402. e4, 2018
The Structure of Ca2+ Sensor Case16 Reveals the Mechanism of Reaction to Low Ca2+ Concentrations
L Leder, W Stark, F Freuler, M Marsh, M Meyerhofer, T Stettler, LM Mayr, ...
Sensors 10 (9), 8143-8160, 2010
Crystal structures of Cg1458 reveal a catalytic lid domain and a common catalytic mechanism for the FAH family
T Ran, Y Gao, M Marsh, W Zhu, M Wang, X Mao, L Xu, D Xu, W Wang
Biochemical Journal 449 (1), 51-60, 2013
Comprehensive analysis of binding sites in tubulin
T Mühlethaler, D Gioia, AE Prota, ME Sharpe, A Cavalli, MO Steinmetz
Angewandte Chemie 133 (24), 13443-13454, 2021
A small-molecule inhibitor of the BRCA2-RAD51 interaction modulates RAD51 assembly and potentiates DNA damage-induced cell death
DE Scott, NJ Francis-Newton, ME Marsh, AG Coyne, G Fischer, ...
Cell chemical biology 28 (6), 835-847. e5, 2021
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