| Functionalized 3-amino-imidazo [1, 2-a] pyridines: a novel class of drug-like Mycobacterium tuberculosis glutamine synthetase inhibitors LR Odell, MT Nilsson, J Gising, O Lagerlund, D Muthas, A Nordqvist, ... Bioorganic & Medicinal Chemistry Letters 19 (16), 4790-4793, 2009 | 128 | 2009 |
| Trisubstituted Imidazoles as Mycobacterium tuberculosis Glutamine Synthetase Inhibitors J Gising, MT Nilsson, LR Odell, S Yahiaoui, M Lindh, H Iyer, AM Sinha, ... Journal of medicinal chemistry 55 (6), 2894-2898, 2012 | 82 | 2012 |
| Microwave-assisted synthesis of small molecules targeting the infectious diseases tuberculosis, HIV/AIDS, malaria and hepatitis C J Gising, LR Odell, M Larhed Organic & Biomolecular Chemistry 10 (14), 2713-2729, 2012 | 50 | 2012 |
| Synthesis, biological evaluation and X-ray crystallographic studies of imidazo [1, 2-a] pyridine-based Mycobacterium tuberculosis glutamine synthetase inhibitors A Nordqvist, MT Nilsson, O Lagerlund, D Muthas, J Gising, S Yahiaoui, ... MedChemComm 3 (5), 620-626, 2012 | 48 | 2012 |
| A straightforward microwave method for rapid synthesis of N-1, C-6 functionalized 3, 5-dichloro-2 (1 H)-pyrazinones J Gising, P Örtqvist, A Sandström, M Larhed Organic & Biomolecular Chemistry 7 (13), 2809-2815, 2009 | 37 | 2009 |
| Direct palladium (II)-catalyzed synthesis of arylamidines from aryltrifluoroborates J Savmarker, J Rydfjord, J Gising, LR Odell, M Larhed Organic Letters 14 (9), 2394-2397, 2012 | 34 | 2012 |
| Achiral pyrazinone-based inhibitors of the hepatitis C virus NS3 protease and drug-resistant variants with elongated substituents directed toward the S2 pocket J Gising, AK Belfrage, H Alogheli, A Ehrenberg, E Åkerblom, R Svensson, ... Journal of Medicinal Chemistry 57 (5), 1790-1801, 2014 | 28 | 2014 |
| Discovery of achiral inhibitors of the hepatitis C virus NS3 protease based on 2(1H)-pyrazinones P Örtqvist, J Gising, AE Ehrenberg, A Vema, A Borg, A Karlén, M Larhed, ... Bioorganic & medicinal chemistry 18 (17), 6512-6525, 2010 | 24 | 2010 |
| Variations of the P2 group in HIV-1 protease inhibitors containing a tertiary alcohol in the transition-state mimicking scaffold JK Ekegren, J Gising, H Wallberg, M Larhed, B Samuelsson, A Hallberg Organic & Biomolecular Chemistry 4 (16), 3040-3043, 2006 | 22 | 2006 |
| Optimization and Evaluation of 5‐Styryl‐Oxathiazol‐2‐one Mycobacterium tuberculosis Proteasome Inhibitors as Potential Antitubercular Agents F Russo, J Gising, L Åkerbladh, AK Roos, A Naworyta, SL Mowbray, ... ChemistryOpen 4 (3), 342-362, 2015 | 18 | 2015 |
| Design, synthesis and in vitro biological evaluation of oligopeptides targeting E. coli type I signal peptidase (LepB) M De Rosa, L Lu, E Zamaratski, N Szałaj, S Cao, H Wadensten, ... Bioorganic & Medicinal Chemistry 25 (3), 897-911, 2017 | 16 | 2017 |
| Structural features determining the intestinal epithelial permeability and efflux of novel HIV-1 protease inhibitors L Lazorova, I Hubatsch, JK Ekegren, J Gising, D Nakai, NM Zaki, ... Journal of pharmaceutical sciences 100 (9), 3763-3772, 2011 | 13 | 2011 |
| Efficient and Selective Palladium‐Catalysed C‐3 Urea Couplings to 3,5‐Dichloro‐2(1H)‐pyrazinones AK Belfrage, J Gising, F Svensson, E Åkerblom, C Sköld, A Sandström European Journal of Organic Chemistry 2015 (5), 978-986, 2015 | 12 | 2015 |
| A Series of Analogues to the AT2R Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode R Isaksson, J Lindman, J Wannberg, J Sallander, M Backlund, D Baraldi, ... ChemistryOpen 8 (1), 114-125, 2019 | 9 | 2019 |
| Syntheses of new tuberculosis inhibitors promoted by microwave irradiation M De Rosa, J Gising, LR Odell, M Larhed Upsala Journal of Medical Sciences 119 (2), 181-191, 2014 | 9 | 2014 |
| Discovery of pyrazinone based compounds that potently inhibit the drug-resistant enzyme variant R155K of the hepatitis C virus NS3 protease AK Belfrage, E Abdurakhmanov, E Åkerblom, P Brandt, A Oshalim, ... Bioorganic & Medicinal Chemistry 24 (12), 2603-2620, 2016 | 7 | 2016 |
| ENABLE: an engine for European antibacterial drug discovery and development M Olliver, L Griestop, D Hughes, AK Belfrage, J Gising, P Baranczewski, ... Nature Reviews Drug Discovery 20 (6), 407-408, 2021 | 6 | 2021 |
| N-(Methyloxycarbonyl) thiophene sulfonamides as high affinity AT2 receptor ligands J Wannberg, J Gising, J Lindman, J Salander, H Gutiérrez-de-Terán, ... Bioorganic & Medicinal Chemistry 29, 115859, 2021 | 6 | 2021 |
| 2-Alkyl substituted benzimidazoles as a new class of selective AT2 receptor ligands T Roy, NN Petersen, G Gopalan, J Gising, M Hallberg, M Larhed Bioorganic & Medicinal Chemistry 66, 116804, 2022 | 4 | 2022 |
| Diastereoselective Synthesis of N-Methylspiroindolines by Intramolecular Mizoroki–Heck Annulations J Lindman, G Gopalan, C Palo-Nieto, P Brandt, J Gising, M Larhed ACS omega 7 (36), 32525-32535, 2022 | 2 | 2022 |
