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Todd Macfarlan
Todd Macfarlan
Verified email at nih.gov
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Cited by
Year
Embryonic stem cell potency fluctuates with endogenous retrovirus activity
TS Macfarlan, WD Gifford, S Driscoll, K Lettieri, HM Rowe, D Bonanomi, ...
Nature 487 (7405), 57-63, 2012
11032012
Ten things you should know about transposable elements
G Bourque, KH Burns, M Gehring, V Gorbunova, A Seluanov, M Hammell, ...
Genome biology 19, 1-12, 2018
10042018
Ataxin-3 is a histone-binding protein with two independent transcriptional corepressor activities
F Li, T Macfarlan, RN Pittman, D Chakravarti
Journal of Biological Chemistry 277 (47), 45004-45012, 2002
2932002
Endogenous retroviruses and neighboring genes are coordinately repressed by LSD1/KDM1A
TS Macfarlan, WD Gifford, S Agarwal, S Driscoll, K Lettieri, J Wang, ...
Genes & development 25 (6), 594-607, 2011
2672011
Long terminal repeats: from parasitic elements to building blocks of the transcriptional regulatory repertoire
PJ Thompson, TS Macfarlan, MC Lorincz
Molecular cell 62 (5), 766-776, 2016
2652016
Enhancer priming by H3K4 methyltransferase MLL4 controls cell fate transition
C Wang, JE Lee, B Lai, TS Macfarlan, S Xu, L Zhuang, C Liu, W Peng, ...
Proceedings of the National Academy of Sciences 113 (42), 11871-11876, 2016
2152016
Chromatin binding of SRp20 and ASF/SF2 and dissociation from mitotic chromosomes is modulated by histone H3 serine 10 phosphorylation
RJ Loomis, Y Naoe, JB Parker, V Savic, MR Bozovsky, T Macfarlan, ...
Molecular cell 33 (4), 450-461, 2009
2152009
TRIM28 repression of retrotransposon-based enhancers is necessary to preserve transcriptional dynamics in embryonic stem cells
HM Rowe, A Kapopoulou, A Corsinotti, L Fasching, TS Macfarlan, ...
Genome research 23 (3), 452-461, 2013
1832013
The KRAB zinc finger protein ZFP809 is required to initiate epigenetic silencing of endogenous retroviruses
G Wolf, P Yang, AC Füchtbauer, EM Füchtbauer, AM Silva, C Park, W Wu, ...
Genes & development 29 (5), 538-554, 2015
1822015
The role of KRAB-ZFPs in transposable element repression and mammalian evolution
P Yang, Y Wang, TS Macfarlan
Trends in Genetics 33 (11), 871-881, 2017
1812017
Regulation of histone acetylation and transcription by nuclear protein pp32, a subunit of the INHAT complex
S Seo, T Macfarlan, P McNamara, R Hong, Y Mukai, S Heo, D Chakravarti
Journal of Biological Chemistry 277 (16), 14005-14010, 2002
1632002
Transposable elements as genetic regulatory substrates in early development
WD Gifford, SL Pfaff, TS Macfarlan
Trends in cell biology 23 (5), 218-226, 2013
1592013
Deficiency of microRNA miR-34a expands cell fate potential in pluripotent stem cells
YJ Choi, CP Lin, D Risso, S Chen, TA Kim, MH Tan, JB Li, Y Wu, C Chen, ...
Science 355 (6325), eaag1927, 2017
1482017
LSD1n is an H4K20 demethylase regulating memory formation via transcriptional elongation control
J Wang, F Telese, Y Tan, W Li, C Jin, X He, H Basnet, Q Ma, D Merkurjev, ...
Nature neuroscience 18 (9), 1256-1264, 2015
1482015
Transposable elements shape the evolution of mammalian development
AD Senft, TS Macfarlan
Nature Reviews Genetics 22 (11), 691-711, 2021
1472021
A signaling role of histone-binding proteins and INHAT subunits pp32 and Set/TAF-Iβ in integrating chromatin hypoacetylation and transcriptional repression
SN Kutney, R Hong, T Macfarlan, D Chakravarti
Journal of Biological Chemistry 279 (29), 30850-30855, 2004
1132004
Spotting the enemy within: Targeted silencing of foreign DNA in mammalian genomes by the Krüppel-associated box zinc finger protein family
G Wolf, D Greenberg, TS Macfarlan
Mobile Dna 6, 1-20, 2015
1092015
DUX-miR-344-ZMYM2-mediated activation of MERVL LTRs induces a totipotent 2C-like state
F Yang, X Huang, R Zang, J Chen, M Fidalgo, C Sanchez-Priego, J Yang, ...
Cell stem cell 26 (2), 234-250. e7, 2020
1012020
Functional and antigenic characterization of human, rhesus macaque, pigtailed macaque, and murine DC-SIGN
F Baribaud, S Pöhlmann, T Sparwasser, MTY Kimata, YK Choi, ...
Journal of virology 75 (21), 10281-10289, 2001
1002001
The arms race between KRAB–zinc finger proteins and endogenous retroelements and its impact on mammals
M Bruno, M Mahgoub, TS Macfarlan
Annual Review of Genetics 53, 393-416, 2019
972019
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