Chromodomain Y-like protein–mediated histone crotonylation regulates stress-induced depressive behaviors Y Liu, M Li, M Fan, Y Song, H Yu, X Zhi, K Xiao, S Lai, J Zhang, X Jin, ... Biological Psychiatry 85 (8), 635-649, 2019 | 85 | 2019 |
Severe deficiency of the voltage-gated sodium channel NaV1. 2 elevates neuronal excitability in adult mice J Zhang, X Chen, M Eaton, J Wu, Z Ma, S Lai, A Park, TS Ahmad, Z Que, ... Cell reports 36 (5), 2021 | 45 | 2021 |
Deficiency of anti-inflammatory cytokine IL-4 leads to neural hyperexcitability and aggravates cerebral ischemia–reperfusion injury X Chen, J Zhang, Y Song, P Yang, Y Yang, Z Huang, K Wang Acta Pharmaceutica Sinica B 10 (9), 1634-1645, 2020 | 40 | 2020 |
Hyperexcitability and pharmacological responsiveness of cortical neurons derived from human iPSCs carrying epilepsy-associated sodium channel Nav1. 2-L1342P genetic variant Z Que, MI Olivero-Acosta, J Zhang, M Eaton, AM Tukker, X Chen, J Wu, ... Journal of Neuroscience 41 (49), 10194-10208, 2021 | 30 | 2021 |
Traumatic stress produces delayed alterations of synaptic plasticity in basolateral amygdala HH Zhang, SQ Meng, XY Guo, JL Zhang, W Zhang, YY Chen, L Lu, ... Frontiers in psychology 10, 2394, 2019 | 21 | 2019 |
Generation and basic characterization of a gene‐trap knockout mouse model of Scn2a with a substantial reduction of voltage‐gated sodium channel Nav1.2 … M Eaton, J Zhang, Z Ma, AC Park, E Lietzke, CM Romero, Y Liu, ... Genes, Brain and Behavior 20 (4), e12725, 2021 | 18 | 2021 |
Deficiency of autism-related Scn2a gene in mice disrupts sleep patterns and circadian rhythms Z Ma, M Eaton, Y Liu, J Zhang, X Chen, X Tu, Y Shi, Z Que, ... Neurobiology of disease 168, 105690, 2022 | 16 | 2022 |
ERG3 potassium channel‐mediated suppression of neuronal intrinsic excitability and prevention of seizure generation in mice K Xiao, Z Sun, X Jin, W Ma, Y Song, S Lai, Q Chen, M Fan, J Zhang, ... The Journal of physiology 596 (19), 4729-4752, 2018 | 11 | 2018 |
Anticonvulsant effect of dipropofol by enhancing native GABA currents in cortical neurons in mice J Zhang, X Chen, M Kårbø, Y Zhao, L An, R Wang, KW Wang, Z Huang Journal of neurophysiology 120 (3), 1404-1414, 2018 | 11 | 2018 |
Inhibition of intracellular proton-sensitive Ca2+-permeable TRPV3 channels protects against ischemic brain injury X Chen, J Zhang, KW Wang Acta Pharmaceutica Sinica B 12 (5), 2330-2347, 2022 | 10 | 2022 |
PKA-RIIβ autophosphorylation modulates PKA activity and seizure phenotypes in mice J Zhang, C Zhang, X Chen, B Wang, W Ma, Y Yang, R Zheng, Z Huang Communications Biology 4 (1), 263, 2021 | 5 | 2021 |
Microglial over-pruning of synapses during development in autism-associated SCN2A-deficient mice and human cerebral organoids Y Yang, J Wu, J Zhang, X Chen, Z Que, K Wettschurack, B Deming, N Cui, ... Research Square, 2023 | 3 | 2023 |
Multi-Electrode Array of Sensory Neurons as an In Vitro Platform to Identify the Nociceptive Response to Pharmaceutical Buffer Systems of Injectable Biologics M Eaton, Z Que, J Zhang, K Beck, R Shi, J McDermott, M Ladisch, Y Yang Pharmaceutical Research 38, 1179-1186, 2021 | 3 | 2021 |
Human iPSC-derived microglia sense and dampen hyperexcitability of cortical neurons carrying the epilepsy-associated SCN2A-L1342P mutation Z Que, MI Olivero-Acosta, I Chen, J Zhang, K Wettschurack, J Wu, T Xiao, ... bioRxiv, 2023 | 1 | 2023 |
002C-3 protects the brain against ischemia-reperfusion injury by inhibiting autophagy and stimulating CaMKK/CaMKIV/HDAC4 pathways in mice J Zhang, T Hu, X Liu, Y Zhu, X Chen, Y Liu, Y Wang | | 2016 |
Anti-thrombotic effect of W007B, a newly synthesized compound, in vitro and in vivo K Hu, X Liu, Y Zhu, J Zhang, Y Liu, Y Wang | | 2014 |
Intervention of multiple pathways by multiple active components provides potent protection against cerebral ischemia injury J Zhang, T Hu, X Liu, Y Zhu, Y Wang | | 2014 |