| Revealing the macromolecular targets of complex natural products D Reker, AM Perna, T Rodrigues, P Schneider, M Reutlinger, B Mönch, ... Nature chemistry 6 (12), 1072-1078, 2014 | 123 | 2014 |
| Therapeutic modulators of peroxisome proliferator-activated receptors (PPAR): a patent review (2008–present) C Lamers, M Schubert-Zsilavecz, D Merk Expert opinion on therapeutic patents 22 (7), 803-841, 2012 | 71 | 2012 |
| Nonacidic farnesoid X receptor modulators D Flesch, SY Cheung, J Schmidt, M Gabler, P Heitel, J Kramer, A Kaiser, ... Journal of Medicinal Chemistry 60 (16), 7199-7205, 2017 | 59 | 2017 |
| Extending the structure–activity relationship of anthranilic acid derivatives as Farnesoid X receptor modulators: Development of a highly potent partial Farnesoid X receptor … D Merk, C Lamers, K Ahmad, R Carrasco Gomez, G Schneider, ... Journal of Medicinal Chemistry 57 (19), 8035-8055, 2014 | 55 | 2014 |
| Molecular tuning of farnesoid X receptor partial agonism D Merk, S Sreeramulu, D Kudlinzki, K Saxena, V Linhard, SL Gande, ... Nature Communications 10 (1), 2915, 2019 | 51 | 2019 |
| N-Benzylbenzamides: A Novel Merged Scaffold for Orally Available Dual Soluble Epoxide Hydrolase/Peroxisome Proliferator-Activated Receptor γ Modulators R Blöcher, C Lamers, SK Wittmann, D Merk, M Hartmann, L Weizel, ... Journal of medicinal chemistry 59 (1), 61-81, 2016 | 45 | 2016 |
| Macrocyclization strategies for cyclic peptides and peptidomimetics C Bechtler, C Lamers RSC Medicinal Chemistry 12 (8), 1325-1351, 2021 | 42 | 2021 |
| Cyclic peptide FXII inhibitor provides safe anticoagulation in a thrombosis model and in artificial lungs J Wilbs, XD Kong, SJ Middendorp, R Prince, A Cooke, CT Demarest, ... Nature communications 11 (1), 3890, 2020 | 39 | 2020 |
| Anthranilic acid derivatives as novel ligands for farnesoid X receptor (FXR) D Merk, M Gabler, RC Gomez, D Flesch, T Hanke, A Kaiser, C Lamers, ... Bioorganic & medicinal chemistry 22 (8), 2447-2460, 2014 | 34 | 2014 |
| Medicinal chemistry and pharmacological effects of Farnesoid X Receptor (FXR) antagonists C Lamers, M Schubert-Zsilavecz, D Merk Current topics in medicinal chemistry 14 (19), 2188-2205, 2014 | 32 | 2014 |
| Anthranilic acid derivatives as nuclear receptor modulators—Development of novel PPAR selective and dual PPAR/FXR ligands D Merk, C Lamers, J Weber, D Flesch, M Gabler, E Proschak, ... Bioorganic & medicinal chemistry 23 (3), 499-514, 2015 | 29 | 2015 |
| Design and synthesis of dual modulators of soluble epoxide hydrolase and peroxisome proliferator-activated receptors E Buscató, R Blöcher, C Lamers, FM Klingler, S Hahn, D Steinhilber, ... Journal of medicinal chemistry 55 (23), 10771-10775, 2012 | 27 | 2012 |
| The promiscuous profile of complement receptor 3 in ligand binding, immune modulation, and pathophysiology C Lamers, CJ Plüss, D Ricklin Frontiers in Immunology 12, 662164, 2021 | 23 | 2021 |
| Compstatins: the dawn of clinical C3-targeted complement inhibition C Lamers, DC Mastellos, D Ricklin, JD Lambris Trends in Pharmacological Sciences, 2022 | 20 | 2022 |
| Novel prostaglandin receptor modulators–Part II: EP receptor modulators; a patent review (2002–2012) D Flesch, D Merk, C Lamers, M Schubert-Zsilavecz Expert opinion on therapeutic patents 23 (2), 233-267, 2013 | 15 | 2013 |
| Identification of pirinixic acid derivatives bearing a 2-aminothiazole moiety combines dual PPARα/γ activation and dual 5-LO/mPGES-1 inhibition T Hanke, C Lamers, RC Gomez, G Schneider, O Werz, ... Bioorganic & medicinal chemistry letters 24 (16), 3757-3763, 2014 | 13 | 2014 |
| Novel prostaglandin receptor modulators: a patent review (2002–2012)–part I: non-EP receptor modulators C Lamers, D Flesch, M Schubert-Zsilavecz, D Merk Expert opinion on therapeutic patents 23 (1), 47-77, 2013 | 12 | 2013 |
| SAR studies on FXR modulators led to the discovery of the first combined FXR antagonistic/TGR5 agonistic compound C Lamers, D Merk, M Gabler, D Flesch, A Kaiser, M Schubert-Zsilavecz Future medicinal chemistry 8 (2), 133-148, 2016 | 10 | 2016 |
| Molecular determinants for improved activity at PPARα: Structure–activity relationship of pirinixic acid derivatives, docking study and site-directed mutagenesis of PPARα C Lamers, M Dittrich, R Steri, E Proschak, M Schubert-Zsilavecz Bioorganic & Medicinal Chemistry Letters 24 (16), 4048-4052, 2014 | 10 | 2014 |
| Design and synthesis of fused soluble epoxide hydrolase/peroxisome proliferator-activated receptor modulators R Blöcher, C Lamers, SK Wittmann, O Diehl, T Hanke, D Merk, ... MedChemComm 7 (6), 1209-1216, 2016 | 7 | 2016 |
