| The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism JM Murphy, PE Czabotar, JM Hildebrand, IS Lucet, JG Zhang, ... Immunity 39 (3), 443-453, 2013 | 1141 | 2013 |
| Robust hyperparameter estimation protects against hypervariable genes and improves power to detect differential expression B Phipson, S Lee, IJ Majewski, WS Alexander, GK Smyth The annals of applied statistics 10 (2), 946, 2016 | 896 | 2016 |
| Molecular patterns of response and treatment failure after frontline venetoclax combinations in older patients with AML CD DiNardo, IS Tiong, A Quaglieri, S MacRaild, S Loghavi, FC Brown, ... Blood, The Journal of the American Society of Hematology 135 (11), 791-803, 2020 | 470 | 2020 |
| Colorectal cancer intrinsic subtypes predict chemotherapy benefit, deficient mismatch repair and epithelial‐to‐mesenchymal transition P Roepman, A Schlicker, J Tabernero, I Majewski, S Tian, V Moreno, ... International journal of cancer 134 (3), 552-562, 2014 | 401 | 2014 |
| Acquisition of the recurrent Gly101Val mutation in BCL2 confers resistance to venetoclax in patients with progressive chronic lymphocytic leukemia P Blombery, MA Anderson, J Gong, R Thijssen, RW Birkinshaw, ... Cancer discovery 9 (3), 342-353, 2019 | 379 | 2019 |
| ChIP-seq analysis reveals distinct H3K27me3 profiles that correlate with transcriptional activity MD Young, TA Willson, MJ Wakefield, E Trounson, DJ Hilton, ME Blewitt, ... Nucleic acids research 39 (17), 7415-7427, 2011 | 341 | 2011 |
| The BCL2 selective inhibitor venetoclax induces rapid onset apoptosis of CLL cells in patients via a TP53-independent mechanism MA Anderson, J Deng, JF Seymour, C Tam, SY Kim, J Fein, L Yu, ... Blood, The Journal of the American Society of Hematology 127 (25), 3215-3224, 2016 | 322 | 2016 |
| PIK3CA mutations are associated with decreased benefit to neoadjuvant human epidermal growth factor receptor 2–targeted therapies in breast cancer IJ Majewski, P Nuciforo, L Mittempergher, AJ Bosma, H Eidtmann, ... Journal of Clinical Oncology 33 (12), 1334, 2015 | 252 | 2015 |
| An α‐E‐catenin (CTNNA1) mutation in hereditary diffuse gastric cancer IJ Majewski, I Kluijt, A Cats, TS Scerri, D de Jong, RJC Kluin, S Hansford, ... The Journal of pathology 229 (4), 621-629, 2013 | 234 | 2013 |
| Mechanisms of therapy resistance in patient-derived xenograft models of BRCA1-deficient breast cancer P Ter Brugge, P Kristel, E Van Der Burg, U Boon, M De Maaker, E Lips, ... Journal of the National Cancer Institute 108 (11), djw148, 2016 | 198 | 2016 |
| Integration of genomic, transcriptomic and proteomic data identifies two biologically distinct subtypes of invasive lobular breast cancer M Michaut, SF Chin, I Majewski, TM Severson, T Bismeijer, L De Koning, ... Scientific reports 6 (1), 1-13, 2016 | 191 | 2016 |
| PIK3CA mutations are associated with reduced pathological complete response rates in primary HER2-positive breast cancer: pooled analysis of 967 patients from five prospective … S Loibl, I Majewski, V Guarneri, V Nekljudova, E Holmes, E Bria, ... Annals of Oncology 27 (8), 1519-1525, 2016 | 190 | 2016 |
| Structures of BCL-2 in complex with venetoclax reveal the molecular basis of resistance mutations RW Birkinshaw, J Gong, CS Luo, D Lio, CA White, MA Anderson, ... Nature communications 10 (1), 2385, 2019 | 167 | 2019 |
| JAFFA: High sensitivity transcriptome-focused fusion gene detection NM Davidson, IJ Majewski, A Oshlack Genome medicine 7, 1-12, 2015 | 162 | 2015 |
| Opposing roles of polycomb repressive complexes in hematopoietic stem and progenitor cells IJ Majewski, ME Ritchie, B Phipson, J Corbin, M Pakusch, A Ebert, ... Blood, The Journal of the American Society of Hematology 116 (5), 731-739, 2010 | 159 | 2010 |
| Identification of recurrent FGFR3 fusion genes in lung cancer through kinome‐centred RNA sequencing IJ Majewski, L Mittempergher, NM Davidson, A Bosma, SM Willems, ... The Journal of pathology 230 (3), 270-276, 2013 | 145 | 2013 |
| Chemotherapy and venetoclax in elderly acute myeloid leukemia trial (CAVEAT): a phase Ib dose-escalation study of venetoclax combined with modified intensive chemotherapy CC Chua, AW Roberts, J Reynolds, CY Fong, SB Ting, JM Salmon, ... Journal of Clinical Oncology 38 (30), 3506-3517, 2020 | 134 | 2020 |
| Polycomb repressive complex 2 (PRC2) restricts hematopoietic stem cell activity IJ Majewski, ME Blewitt, CA de Graaf, EJ McManus, M Bahlo, AA Hilton, ... PLoS biology 6 (4), e93, 2008 | 124 | 2008 |
| Taming the dragon: genomic biomarkers to individualize the treatment of cancer IJ Majewski, R Bernards Nature medicine 17 (3), 304-312, 2011 | 117 | 2011 |
| Comprehensive characterization of single-cell full-length isoforms in human and mouse with long-read sequencing L Tian, JS Jabbari, R Thijssen, Q Gouil, SL Amarasinghe, O Voogd, ... Genome biology 22, 1-24, 2021 | 111 | 2021 |
