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Bryan P. Simpson, PhD
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Year
Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain
BE Deverman, PL Pravdo, BP Simpson, SR Kumar, KY Chan, A Banerjee, ...
Nature biotechnology 34 (2), 204-209, 2016
9282016
Targeted long-read sequencing captures CRISPR editing and AAV integration outcomes in brain
BP Simpson, CM Yrigollen, A Izda, BL Davidson
Molecular Therapy 31 (3), 760-773, 2023
122023
CRISPR–Cas Gene Editing for Neurological Disease
BP Simpson, BL Davidson
Nervous System Drug Delivery, 365-376, 2019
12019
Compositions and methods for treating fragile X syndrome and related syndromes
BL Davidson, CM Yrigollen, A Monteys, B Simpson
US Patent 11,497,816, 2022
2022
Crispr/cas9 gene editing of atxn2 for the treatment of spinocerebellar ataxia type 2
B Simpson, B Davidson, AM Monteys
US Patent App. 17/594,651, 2022
2022
The Molecular and Behavioral Phenotypes Altered in CGG Knock-In Mice Edited Using CRISPR
CM Yrigollen, B Simpson, E Lim, YH Chen, B Davidson
MOLECULAR THERAPY 30 (4), 135-135, 2022
2022
Long-Read Nanopore Sequencing Reveals Outcomes of AAV-CRISPR Editing in the Brain of Transgenic Mouse Models
BP Simpson, CM Yrigollen, PT Ranum, BL Davidson
MOLECULAR THERAPY 30 (4), 390-391, 2022
2022
Using Nanopore Sequencing to Characterize On-Target CRISPR-Mediated Gene Editing
BP Simpson, CM Yrigollen, PT Ranum, BL Davidson
MOLECULAR THERAPY 28 (4), 278-279, 2020
2020
CRISPR-Cas9 Gene Editing Strategies of ATXN2 for the Treatment of Spinocerebellar Ataxia Type 2
BP Simpson, MS Keiser, AM Monteys, BL Davidson
MOLECULAR THERAPY 27 (4), 112-112, 2019
2019
252. Using Cre-Dependent In Vivo Selection to Identify AAV Variants That Enable Efficient and Widespread Gene Transfer to the Adult Central Nervous System
BE Deverman, PL Pravdo, BP Simpson, SR Kumar, Y Luo, KY Chan, ...
Molecular Therapy 24, S99, 2016
2016
Engineering Recombinant AAV Vectors for More Efficient and Restricted Gene Expression in the CNS after Systemic Administration
BE Deverman, B Simpson, P Pravdo, A Banerjee, PH Patterson
MOLECULAR THERAPY 22, S118-S118, 2014
2014
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Articles 1–11