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Tea Pemovska, PhD
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Individualized systems medicine strategy to tailor treatments for patients with chemorefractory acute myeloid leukemia
T Pemovska, M Kontro, B Yadav, H Edgren, S Eldfors, A Szwajda, ...
Cancer discovery 3 (12), 1416-1429, 2013
449*2013
Quantitative scoring of differential drug sensitivity for individually optimized anticancer therapies
B Yadav, T Pemovska, A Szwajda, E Kulesskiy, M Kontro, R Karjalainen, ...
Scientific reports 4 (1), 1-10, 2014
3192014
Axitinib effectively inhibits BCR-ABL1 (T315I) with a distinct binding conformation
T Pemovska, E Johnson, M Kontro, GA Repasky, J Chen, P Wells, ...
Nature 519 (7541), 102-105, 2015
2632015
Novel activating STAT5B mutations as putative drivers of T-cell acute lymphoblastic leukemia
M Kontro, H Kuusanmäki, S Eldfors, T Burmeister, EI Andersson, ...
Leukemia 28 (8), 1738-1742, 2014
1262014
Proposed diagnostic criteria for classical chronic myelomonocytic leukemia (CMML), CMML variants and pre-CMML conditions
P Valent, A Orazi, MR Savona, MM Patnaik, F Onida, ...
haematologica 104 (10), 1935, 2019
1242019
JAK1/2 and BCL2 inhibitors synergize to counteract bone marrow stromal cell–induced protection of AML
R Karjalainen, T Pemovska, M Popa, M Liu, KK Javarappa, MM Majumder, ...
Blood, The Journal of the American Society of Hematology 130 (6), 789-802, 2017
1222017
Recent advances in combinatorial drug screening and synergy scoring
T Pemovska, JW Bigenzahn, G Superti-Furga
Current opinion in pharmacology 42, 102-110, 2018
1022018
HOX gene expression predicts response to BCL-2 inhibition in acute myeloid leukemia
M Kontro, A Kumar, MM Majumder, S Eldfors, A Parsons, T Pemovska, ...
Leukemia 31 (2), 301-309, 2017
892017
Functional Precision Medicine Provides Clinical Benefit in Advanced Aggressive Hematological Cancers and Identifies Exceptional Responders
C Kornauth, T Pemovska, GI Vladimer, G Bayer, M Bergmann, S Eder, ...
Cancer discovery, candisc. 0538.2021, 2021
862021
Discovery of novel drug sensitivities in T-PLL by high-throughput ex vivo drug testing and mutation profiling
EI Andersson, S Pützer, B Yadav, O Dufva, S Khan, L He, L Sellner, ...
Leukemia 32 (3), 774-787, 2018
862018
Enhanced sensitivity to glucocorticoids in cytarabine-resistant AML
D Malani, A Murumägi, B Yadav, M Kontro, S Eldfors, A Kumar, ...
Leukemia 31 (5), 1187-1195, 2017
542017
Idelalisib sensitivity and mechanisms of disease progression in relapsed TCF3-PBX1 acute lymphoblastic leukemia
S Eldfors, H Kuusanmäki, M Kontro, MM Majumder, A Parsons, H Edgren, ...
Leukemia 31 (1), 51-57, 2017
532017
Development of metastatic HER2+ breast cancer is independent of the adaptive immune system
M Ciampricotti, K Vrijland, CS Hau, T Pemovska, CW Doornebal, ...
The Journal of pathology 224 (1), 56-66, 2011
412011
Combined chemosensitivity and chromatin profiling prioritizes drug combinations in CLL
C Schmidl, GI Vladimer, AF Rendeiro, S Schnabl, T Krausgruber, ...
Nature chemical biology 15 (3), 232-240, 2019
392019
Novel drug candidates for blast phase chronic myeloid leukemia from high-throughput drug sensitivity and resistance testing
PO Pietarinen, T Pemovska, M Kontro, B Yadav, JP Mpindi, EI Andersson, ...
Blood cancer journal 5 (5), e309-e309, 2015
352015
From drug response profiling to target addiction scoring in cancer cell models
B Yadav, P Gopalacharyulu, T Pemovska, SA Khan, A Szwajda, J Tang, ...
Disease models & mechanisms 8 (10), 1255-1264, 2015
202015
Differentiation status of primary chronic myeloid leukemia cells affects sensitivity to BCR-ABL1 inhibitors
PO Pietarinen, CA Eide, P Ayuda-Durán, S Potdar, H Kuusanmäki, ...
Oncotarget 8 (14), 22606, 2017
192017
8‐chloro‐adenosine activity in FLT3‐ITD acute myeloid leukemia
R Buettner, LXT Nguyen, B Kumar, C Morales, C Liu, LS Chen, ...
Journal of cellular physiology 234 (9), 16295-16303, 2019
162019
Core-binding factor leukemia hijacks the T-cell–prone PU. 1 antisense promoter
E van der Kouwe, G Heller, A Czibere, JA Pulikkan, C Agreiter, ...
Blood, The Journal of the American Society of Hematology 138 (15), 1345-1358, 2021
142021
Deep Morphology Learning Enhances Ex Vivo Drug Profiling-Based Precision Medicine
T Heinemann, C Kornauth, Y Severin, GI Vladimer, T Pemovska, ...
Blood Cancer Discovery 3 (6), 502-515, 2022
112022
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Articles 1–20