Deepa Sampath
Deepa Sampath
Associate Professor
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Association of a microRNA/TP53 feedback circuitry with pathogenesis and outcome of B-cell chronic lymphocytic leukemia
M Fabbri, A Bottoni, M Shimizu, R Spizzo, MS Nicoloso, S Rossi, ...
Jama 305 (1), 59-67, 2011
microRNA fingerprinting of CLL patients with chromosome 17p deletion identify a miR-21 score that stratifies early survival
S Rossi, M Shimizu, E Barbarotto, MS Nicoloso, F Dimitri, D Sampath, ...
Blood, The Journal of the American Society of Hematology 116 (6), 945-952, 2010
Mechanisms of apoptosis induction by nucleoside analogs
D Sampath, VA Rao, W Plunkett
Oncogene 22 (56), 9063-9074, 2003
Nucleoside analogs: molecular mechanisms signaling cell death
B Ewald, D Sampath, W Plunkett
Oncogene 27 (50), 6522-6537, 2008
Histone deacetylases mediate the silencing of miR-15a, miR-16, and miR-29b in chronic lymphocytic leukemia
D Sampath, C Liu, K Vasan, M Sulda, VK Puduvalli, WG Wierda, ...
Blood, The Journal of the American Society of Hematology 119 (5), 1162-1172, 2012
H2AX phosphorylation marks gemcitabine-induced stalled replication forks and their collapse upon S-phase checkpoint abrogation
B Ewald, D Sampath, W Plunkett
Molecular cancer therapeutics 6 (4), 1239-1248, 2007
S-Phase arrest by nucleoside analogues and abrogation of survival without cell cycle progression by 7-hydroxystaurosporine
Z Shi, A Azuma, D Sampath, YX Li, P Huang, W Plunkett
Cancer Research 61 (3), 1065-1072, 2001
Effects of nerve growth factor on glutathione peroxidase and catalase in PC 12 cells
D Sampath, GR Jackson, K Werrbach‐Perez, JR Perez‐Polo
Journal of neurochemistry 62 (6), 2476-2479, 1994
Pharmacodynamics of cytarabine alone and in combination with 7-hydroxystaurosporine (UCN-01) in AML blasts in vitro and during a clinical trial
D Sampath, J Cortes, Z Estrov, M Du, Z Shi, M Andreeff, V Gandhi, ...
Blood 107 (6), 2517-2524, 2006
miRNAs and their potential for use against cancer and other diseases
E Tili, JJ Michaille, V Gandhi, W Plunkett, D Sampath, GA Calin
Future Medicine Ltd 3 (5), 521-537, 2007
Specific activation of microRNA106b enables the p73 apoptotic response in chronic lymphocytic leukemia by targeting the ubiquitin ligase Itch for degradation
D Sampath, GA Calin, VK Puduvalli, G Gopisetty, C Taccioli, CG Liu, ...
Blood 113 (16), 3744-3753, 2009
TRAIL-induced apoptosis in gliomas is enhanced by Akt-inhibition and is independent of JNK activation
VK Puduvalli, D Sampath, JM Bruner, J Nangia, R Xu, AP Kyritsis
Apoptosis 10 (1), 233-243, 2005
Inhibition of cyclin-dependent kinase 2 by the Chk1-Cdc25A pathway during the S-phase checkpoint activated by fludarabine: dysregulation by 7-hydroxystaurosporine
D Sampath, Z Shi, W Plunkett
Molecular pharmacology 62 (3), 680-688, 2002
Epigenetic regulation of CD133/PROM1 expression in glioma stem cells by Sp1/myc and promoter methylation
G Gopisetty, J Xu, D Sampath, H Colman, VK Puduvalli
Oncogene 32 (26), 3119-3129, 2013
BRD4 profiling identifies critical chronic lymphocytic leukemia oncogenic circuits and reveals sensitivity to PLX51107, a novel structurally distinct BET inhibitor
HG Ozer, D El-Gamal, B Powell, ZA Hing, JS Blachly, B Harrington, ...
Cancer discovery 8 (4), 458-477, 2018
Design of new anticancer therapies targeting cell cycle checkpoint pathways
D Sampath, W Plunkett
Current opinion in oncology 13 (6), 484-490, 2001
Effects of nerve growth factor on catalase and glutathione peroxidase in a hydrogen peroxide-resistant pheochromocytoma subclone
GR Jackson, D Sampath, K Werrbach-Perez, JR Perez-Polo
Brain research 634 (1), 69-76, 1994
Neurotrophin regulation of energy homeostasis in the central nervous system
GR Jackson, K Werrbach-Perez, Z Pan, D Sampath, JR Perez-Polo
Developmental neuroscience 16 (5-6), 285-290, 1994
ATM and the Mre11-Rad50-Nbs1 complex respond to nucleoside analogue–Induced stalled replication forks and contribute to drug resistance
B Ewald, D Sampath, W Plunkett
Cancer research 68 (19), 7947-7955, 2008
XPO1 inhibition using selinexor synergizes with chemotherapy in acute myeloid leukemia by targeting DNA repair and restoring topoisomerase IIα to the nucleus
P Ranganathan, T Kashyap, X Yu, X Meng, TH Lai, B McNeil, ...
Clinical Cancer Research 22 (24), 6142-6152, 2016
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