| Dendritic function of tau mediates amyloid-β toxicity in Alzheimer's disease mouse models LM Ittner, YD Ke, F Delerue, M Bi, A Gladbach, J van Eersel, H Wölfing, ... Cell 142 (3), 387-397, 2010 | 1894 | 2010 |
| Amyloid-β and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice V Rhein, X Song, A Wiesner, LM Ittner, G Baysang, F Meier, L Ozmen, ... Proceedings of the National Academy of Sciences 106 (47), 20057-20062, 2009 | 679 | 2009 |
| Mitochondrial dysfunction: an early event in Alzheimer pathology accumulates with age in AD transgenic mice S Hauptmann, I Scherping, S Dröse, U Brandt, KL Schulz, M Jendrach, ... Neurobiology of aging 30 (10), 1574-1586, 2009 | 477 | 2009 |
| Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice DC David, S Hauptmann, I Scherping, K Schuessel, U Keil, P Rizzu, ... Journal of Biological Chemistry 280 (25), 23802-23814, 2005 | 426 | 2005 |
| Dietary Cu stabilizes brain superoxide dismutase 1 activity and reduces amyloid Aβ production in APP23 transgenic mice TA Bayer, S Schäfer, A Simons, A Kemmling, T Kamer, R Tepests, ... Proceedings of the National Academy of Sciences 100 (24), 14187-14192, 2003 | 410 | 2003 |
| Brain aging and neurodegeneration: from a mitochondrial point of view A Grimm, A Eckert Journal of neurochemistry 143 (4), 418-431, 2017 | 389 | 2017 |
| Mitochondrial dysfunction, apoptotic cell death, and Alzheimer’s disease A Eckert, U Keil, CA Marques, A Bonert, C Frey, K Schüssel, WE Müller Biochemical pharmacology 66 (8), 1627-1634, 2003 | 370 | 2003 |
| Amyloid β-induced changes in nitric oxide production and mitochondrial activity lead to apoptosis U Keil, A Bonert, CA Marques, I Scherping, J Weyermann, ... Journal of Biological Chemistry 279 (48), 50310-50320, 2004 | 362 | 2004 |
| Amyloid-Beta interaction with mitochondria L Pagani, A Eckert International Journal of Alzheimer’s Disease 2011, 2011 | 355 | 2011 |
| Amyloid-Beta interaction with mitochondria L Pagani, A Eckert International Journal of Alzheimer’s Disease 2011, 2011 | 355 | 2011 |
| Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing SC Cunnane, E Trushina, C Morland, A Prigione, G Casadesus, ... Nature Reviews Drug Discovery 19 (9), 609-633, 2020 | 327 | 2020 |
| ROS generation, lipid peroxidation and antioxidant enzyme activities in the aging brain S Leutner, A Eckert, WE Müller Journal of neural transmission 108, 955-967, 2001 | 281 | 2001 |
| Mitochondrial dysfunction: common final pathway in brain aging and Alzheimer’s disease—therapeutic aspects WE Müller, A Eckert, C Kurz, GP Eckert, K Leuner Molecular neurobiology 41, 159-171, 2010 | 262 | 2010 |
| Effects of EGb 761® Ginkgo biloba extract on mitochondrial function and oxidative stress A Eckert, U Keil, S Kressmann, K Schindowski, S Leutner, S Leutz, ... Pharmacopsychiatry 36 (S 1), 15-23, 2003 | 242 | 2003 |
| Reduced hippocampal MT2 melatonin receptor expression in Alzheimer's disease E Savaskan, MA Ayoub, R Ravid, D Angeloni, F Fraschini, F Meier, ... Journal of pineal research 38 (1), 10-16, 2005 | 241 | 2005 |
| Neurotoxic mechanisms caused by the Alzheimer's disease-linked Swedish amyloid precursor protein mutation: oxidative stress, caspases, and the JNK pathway CA Marques, U Keil, A Bonert, B Steiner, C Haass, WE Muller, A Eckert Journal of biological chemistry 278 (30), 28294-28302, 2003 | 221 | 2003 |
| Neurotoxic mechanisms caused by the Alzheimer's disease-linked Swedish amyloid precursor protein mutation: oxidative stress, caspases, and the JNK pathway CA Marques, U Keil, A Bonert, B Steiner, C Haass, WE Muller, A Eckert Journal of biological chemistry 278 (30), 28294-28302, 2003 | 221 | 2003 |
| Amyloid-beta leads to impaired cellular respiration, energy production and mitochondrial electron chain complex activities in human neuroblastoma cells V Rhein, G Baysang, S Rao, F Meier, A Bonert, F Müller-Spahn, A Eckert Cellular and molecular neurobiology 29, 1063-1071, 2009 | 215 | 2009 |
| Mitochondrial dysfunction: the first domino in brain aging and Alzheimer's disease? K Leuner, S Hauptmann, R Abdel-Kader, I Scherping, U Keil, ... Antioxidants & redox signaling 9 (10), 1659-1676, 2007 | 211 | 2007 |
| Mitochondrial dysfunction-the beginning of the end in Alzheimer's disease? Separate and synergistic modes of tau and amyloid-β toxicity A Eckert, K Schmitt, J Götz Alzheimer's research & therapy 3, 1-11, 2011 | 182 | 2011 |
walter erhard mullerProfessor of pharmacology, University mainz,Mannheim FrankfurtVerified email at em.uni-frankfurt.de
