|Dual role of phosphatidylinositol-3, 4, 5-trisphosphate in the activation of protein kinase B|
D Stokoe, LR Stephens, T Copeland, PRJ Gaffney, CB Reese, GF Painter, ...
Science 277 (5325), 567-570, 1997
|Protein kinase B kinases that mediate phosphatidylinositol 3, 4, 5-trisphosphate-dependent activation of protein kinase B|
L Stephens, K Anderson, D Stokoe, H Erdjument-Bromage, GF Painter, ...
Science 279 (5351), 710-714, 1998
|Natural killer T cells recognize diacylglycerol antigens from pathogenic bacteria|
Y Kinjo, E Tupin, D Wu, M Fujio, R Garcia-Navarro, MREI Benhnia, ...
Nature immunology 7 (9), 978-986, 2006
|Identification of ARAP3, a novel PI3K effector regulating both Arf and Rho GTPases, by selective capture on phosphoinositide affinity matrices|
S Krugmann, KE Anderson, SH Ridley, N Risso, A McGregor, J Coadwell, ...
Molecular cell 9 (1), 95-108, 2002
|The stress-activated phosphatidylinositol 3-phosphate 5-kinase Fab1p is essential for vacuole function in S. cerevisiae|
FT Cooke, SK Dove, RK McEwen, G Painter, AB Holmes, MN Hall, ...
Current biology 8 (22), 1219-S2, 1998
|Femtomolar transition state analogue inhibitors of 5′-methylthioadenosine/S-adenosylhomocysteine nucleosidase from Escherichia coli|
V Singh, GB Evans, DH Lenz, JM Mason, K Clinch, S Mee, GF Painter, ...
Journal of Biological Chemistry 280 (18), 18265-18273, 2005
|Complementation Analysis in PtdInsPKinase-deficient Yeast Mutants Demonstrates ThatSchizosaccharomyces pombe and Murine Fab1p Homologues Are Phosphatidylinositol 3-Phosphate 5 …|
RK McEwen, SK Dove, FT Cooke, GF Painter, AB Holmes, A Shisheva, ...
Journal of Biological Chemistry 274 (48), 33905-33912, 1999
|Soluble CD36 ectodomain binds negatively charged diacylglycerol ligands and acts as a co-receptor for TLR2|
MJ Jimenez-Dalmaroni, N Xiao, AL Corper, P Verdino, GD Ainge, ...
PloS one 4 (10), 2009
|Lipid binding orientation within CD1d affects recognition of Borrelia burgorferi antigens by NKT cells|
J Wang, Y Li, Y Kinjo, TT Mac, D Gibson, GF Painter, M Kronenberg, ...
Proceedings of the National Academy of Sciences 107 (4), 1535-1540, 2010
|The Vα14 invariant natural killer T cell TCR forces microbial glycolipids and CD1d into a conserved binding mode|
Y Li, E Girardi, J Wang, ED Yu, GF Painter, M Kronenberg, DM Zajonc
Journal of Experimental Medicine 207 (11), 2383-2393, 2010
|Primary deficiency of microsomal triglyceride transfer protein in human abetalipoproteinemia is associated with loss of CD1 function|
S Zeissig, SK Dougan, DC Barral, Y Junker, Z Chen, A Kaser, M Ho, ...
The Journal of clinical investigation 120 (8), 2889-2899, 2010
|ILC2s and T cells cooperate to ensure maintenance of M2 macrophages for lung immunity against hookworms|
T Bouchery, R Kyle, M Camberis, A Shepherd, K Filbey, A Smith, M Harvie, ...
Nature communications 6 (1), 1-13, 2015
|Role of phosphatidylinositol mannosides in the interaction between mycobacteria and DC-SIGN|
NN Driessen, R Ummels, JJ Maaskant, SS Gurcha, GS Besra, GD Ainge, ...
Infection and immunity 77 (10), 4538-4547, 2009
|Structural characterization of mycobacterial phosphatidylinositol mannoside binding to mouse CD1d|
DM Zajonc, GD Ainge, GF Painter, WB Severn, IA Wilson
The Journal of Immunology 177 (7), 4577-4583, 2006
|Structure and Inhibition of a Quorum Sensing Target from Streptococcus pneumoniae|
V Singh, W Shi, SC Almo, GB Evans, RH Furneaux, PC Tyler, GF Painter, ...
Biochemistry 45 (43), 12929-12941, 2006
|Second generation transition state analogue inhibitors of human 5 ‘-methylthioadenosine phosphorylase|
GB Evans, RH Furneaux, DH Lenz, GF Painter, VL Schramm, V Singh, ...
Journal of medicinal chemistry 48 (14), 4679-4689, 2005
|Picomolar inhibitors as transition-state probes of 5′-methylthioadenosine nucleosidases|
JA Gutierrez, M Luo, V Singh, L Li, RL Brown, GE Norris, GB Evans, ...
ACS chemical biology 2 (11), 725-734, 2007
|Energetic mapping of transition state analogue interactions with human and Plasmodium falciparum purine nucleoside phosphorylases|
A Lewandowicz, EAT Ringia, LM Ting, K Kim, PC Tyler, GB Evans, ...
Journal of Biological Chemistry 280 (34), 30320-30328, 2005
|General synthesis of 3-phosphorylated myo-inositol phospholipids and derivatives|
GF Painter, SJA Grove, IH Gilbert, AB Holmes, PR Raithby, ML Hill, ...
Journal of the Chemical Society, Perkin Transactions 1, 923-936, 1999
|Syntheses of tetrahydroxyazepanes from chiro-inositols and their evaluation as glycosidase inhibitors|
GF Painter, PJ Eldridge, A Falshaw
Bioorganic & medicinal chemistry 12 (1), 225-232, 2004