walter erhard muller
walter erhard muller
Professor of pharmacology, University mainz,Mannheim Frankfurt
Verified email at
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Hyperforin as a possible antidepressant component of hypericum extracts
SS Chatterjee, SK Bhattacharya, M Wonnemann, A Singer, WE Müller
Life sciences 63 (6), 499-510, 1998
Mitochondrial dysfunction: an early event in Alzheimer pathology accumulates with age in AD transgenic mice
S Hauptmann, I Scherping, S Dröse, U Brandt, KL Schulz, M Jendrach, ...
Neurobiology of aging 30 (10), 1574-1586, 2009
Hyperforin represents the neurotransmitter reuptake inhibiting constituent of hypericum extract
WE Müller, A Singer, M Wonnemann, U Hafner, M Rolli, C Schäfer
Pharmacopsychiatry 31 (S 1), 16-21, 1998
Abuse and dependence potential for the non‐benzodiazepine hypnotics zolpidem and zopiclone: a review of case reports and epidemiological data
G Hajak, WE Müller, HU Wittchen, D Pittrow, W Kirch
Addiction 98 (10), 1371-1378, 2003
The location of drug binding sites in human serum albumin
KJ Fehske, WE Müller, U Wollert
Biochemical Pharmacology 30 (7), 687-692, 1981
Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice
DC David, S Hauptmann, I Scherping, K Schuessel, U Keil, P Rizzu, ...
Journal of Biological Chemistry 280 (25), 23802-23814, 2005
Effects of hypericum extract (LI 160) in biochemical models of antidepressant activity
WE Müller, M Rolli, C Schäfer, U Hafner
Pharmacopsychiatry 30 (S 2), 102-107, 1997
Parkinson phenotype in aged PINK1-deficient mice is accompanied by progressive mitochondrial dysfunction in absence of neurodegeneration
S Gispert, F Ricciardi, A Kurz, M Azizov, HH Hoepken, D Becker, W Voos, ...
PloS one 4 (6), e5777, 2009
Hyperforin, a major antidepressant constituent of St. John’s Wort, inhibits serotonin uptake by elevating free intracellular Na+ 1 1
A Singer, M Wonnemann, WE Müller
Journal of Pharmacology and Experimental Therapeutics 290 (3), 1363-1368, 1999
Mitochondrial dysfunction, apoptotic cell death, and Alzheimer’s disease
A Eckert, U Keil, CA Marques, A Bonert, C Frey, K Schüssel, WE Müller
Biochemical pharmacology 66 (8), 1627-1634, 2003
Amyloid β-induced changes in nitric oxide production and mitochondrial activity lead to apoptosis
U Keil, A Bonert, CA Marques, I Scherping, J Weyermann, ...
Journal of Biological Chemistry 279 (48), 50310-50320, 2004
Current St. John’s wort research from mode of action to clinical efficacy
WE Müller
Pharmacological research 47 (2), 101-109, 2003
Hyperforin is a dual inhibitor of cyclooxygenase-1 and 5-lipoxygenase
D Albert, I Zündorf, T Dingermann, WE Müller, D Steinhilber, O Werz
Biochemical pharmacology 64 (12), 1767-1775, 2002
Mitochondrion-derived reactive oxygen species lead to enhanced amyloid beta formation
K Leuner, T Schütt, C Kurz, SH Eckert, C Schiller, A Occhipinti, S Mai, ...
Antioxidants & redox signaling 16 (12), 1421-1433, 2012
Hyperforin—a key constituent of St. John's wort specifically activates TRPC6 channels
K Leuner, V Kazanski, M Muller, K Essin, B Henke, M Gollasch, ...
The FASEB Journal 21 (14), 4101-4111, 2007
ROS generation, lipid peroxidation and antioxidant enzyme activities in the aging brain
S Leutner, A Eckert, WE Müller
Journal of neural transmission 108, 955-967, 2001
Mitochondrial dysfunction: common final pathway in brain aging and Alzheimer’s disease—therapeutic aspects
WE Müller, A Eckert, C Kurz, GP Eckert, K Leuner
Molecular neurobiology 41, 159-171, 2010
Stratified medicine for mental disorders
G Schumann, EB Binder, A Holte, ER de Kloet, KJ Oedegaard, ...
European Neuropsychopharmacology 24 (1), 5-50, 2014
Effects of EGb 761® Ginkgo biloba extract on mitochondrial function and oxidative stress
A Eckert, U Keil, S Kressmann, K Schindowski, S Leutner, S Leutz, ...
Pharmacopsychiatry 36 (S 1), 15-23, 2003
Statin effects on cholesterol micro-domains in brain plasma membranes
C Kirsch, GP Eckert, WE Mueller
Biochemical pharmacology 65 (5), 843-856, 2003
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