| Long pre-mRNA depletion and RNA missplicing contribute to neuronal vulnerability from loss of TDP-43 M Polymenidou, C Lagier-Tourenne, KR Hutt, SC Huelga, J Moran, ... Nature neuroscience 14 (4), 459-468, 2011 | 1352 | 2011 |
| Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAs C Lagier-Tourenne, M Polymenidou, KR Hutt, AQ Vu, M Baughn, ... Nature neuroscience 15 (11), 1488-1497, 2012 | 805 | 2012 |
| Nuclear receptor-induced chromosomal proximity and DNA breaks underlie specific translocations in cancer C Lin, L Yang, B Tanasa, K Hutt, B Ju, KA Ohgi, J Zhang, DW Rose, XD Fu, ... Cell 139 (6), 1069-1083, 2009 | 664 | 2009 |
| Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration C Lagier-Tourenne, M Baughn, F Rigo, S Sun, P Liu, HR Li, J Jiang, ... Proceedings of the National Academy of Sciences 110 (47), E4530-E4539, 2013 | 659 | 2013 |
| Histone methylation-dependent mechanisms impose ligand dependency for gene activation by nuclear receptors I Garcia-Bassets, YS Kwon, F Telese, GG Prefontaine, KR Hutt, CS Cheng, ... Cell 128 (3), 505-518, 2007 | 504 | 2007 |
| Comprehensive discovery of endogenous Argonaute binding sites in Caenorhabditis elegans DG Zisoulis, MT Lovci, ML Wilbert, KR Hutt, TY Liang, AE Pasquinelli, ... Nature structural & molecular biology 17 (2), 173-179, 2010 | 370 | 2010 |
| Developmentally regulated activation of a SINE B2 repeat as a domain boundary in organogenesis VV Lunyak, GG Prefontaine, E Nunez, T Cramer, BG Ju, KA Ohgi, K Hutt, ... Science 317 (5835), 248-251, 2007 | 321 | 2007 |
| Enhancing nuclear receptor-induced transcription requires nuclear motor and LSD1-dependent gene networking in interchromatin granules Q Hu, YS Kwon, E Nunez, MD Cardamone, KR Hutt, KA Ohgi, ... Proceedings of the National Academy of Sciences 105 (49), 19199-19204, 2008 | 309 | 2008 |
| LIN28 binds messenger RNAs at GGAGA motifs and regulates splicing factor abundance ML Wilbert, SC Huelga, K Kapeli, TJ Stark, TY Liang, SX Chen, BY Yan, ... Molecular cell 48 (2), 195-206, 2012 | 302 | 2012 |
| Misregulated RNA processing in amyotrophic lateral sclerosis M Polymenidou, C Lagier-Tourenne, KR Hutt, CF Bennett, DW Cleveland, ... Brain research 1462, 3-15, 2012 | 204 | 2012 |
| Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses K Kapeli, GA Pratt, AQ Vu, KR Hutt, FJ Martinez, B Sundararaman, ... Nature communications 7 (1), 12143, 2016 | 182 | 2016 |
| Sensitive ChIP-DSL technology reveals an extensive estrogen receptor α-binding program on human gene promoters YS Kwon, I Garcia-Bassets, KR Hutt, CS Cheng, M Jin, D Liu, C Benner, ... Proceedings of the National Academy of Sciences 104 (12), 4852-4857, 2007 | 142 | 2007 |
| Retracted: nuclear receptor-enhanced transcription requires motor-and LSD1-dependent gene networking in interchromatin granules E Nunez, YS Kwon, KR Hutt, Q Hu, MD Cardamone, KA Ohgi, ... Cell 132 (6), 996-1010, 2008 | 73 | 2008 |
| Transcriptome–pathology correlation identifies interplay between TDP-43 and the expression of its kinase CK1E in sporadic ALS F Krach, R Batra, EC Wheeler, AQ Vu, R Wang, K Hutt, SJ Rabin, ... Acta neuropathologica 136, 405-423, 2018 | 72 | 2018 |
| Decoding a signature-based model of transcription cofactor recruitment dictated by cardinal cis-regulatory elements in proximal promoter regions C Benner, S Konovalov, C Mackintosh, KR Hutt, R Stunnenberg, ... PLoS genetics 9 (11), e1003906, 2013 | 46 | 2013 |
| Stability and uniqueness of clonal immunoglobulin CDR3 sequences for MRD tracking in multiple myeloma EH Rustad, K Misund, E Bernard, E Coward, VD Yellapantula, ... American journal of hematology 94 (12), 1364-1373, 2019 | 25 | 2019 |
| Gene expression signatures of sporadic ALS motor neuron populations R Batra, K Hutt, A Vu, SJ Rabin, MW Baughn, RT Libby, S Hoon, J Ravits, ... BioRxiv, 038448, 2016 | 25 | 2016 |
| Routine evaluation of minimal residual disease in myeloma using next-generation sequencing clonality testing: feasibility, challenges, and direct comparison with high … C Ho, M Syed, M Roshal, K Petrova-Drus, C Moung, J Yao, AE Quesada, ... The Journal of Molecular Diagnostics 23 (2), 181-199, 2021 | 21 | 2021 |
| Nxf1 Natural Variant E610G Is a Semi-dominant Suppressor of IAP-Induced RNA Processing Defects D Concepcion, KD Ross, KR Hutt, GW Yeo, BA Hamilton PLoS Genetics 11 (4), e1005123, 2015 | 11 | 2015 |
| Multiplexed transcriptome discovery of RNA-binding protein binding sites by antibody-barcode eCLIP DA Lorenz, HL Her, KA Shen, K Rothamel, KR Hutt, AC Nojadera, ... Nature methods 20 (1), 65-69, 2023 | 8 | 2023 |
Gene Yeo PhD MBAProfessor of Cellular and Molecular Medicine at UC San DiegoAdresse e-mail validée de ucsd.edu
