Genetic assessment of age-associated Alzheimer disease risk: development and validation of a polygenic hazard score RS Desikan, CC Fan, Y Wang, AJ Schork, HJ Cabral, LA Cupples, ... PLoS medicine 14 (3), e1002258, 2017 | 390 | 2017 |
Life extension factor klotho enhances cognition DB Dubal, JS Yokoyama, L Zhu, L Broestl, K Worden, D Wang, VE Sturm, ... Cell reports 7 (4), 1065-1076, 2014 | 341 | 2014 |
Novel loci for major depression identified by genome-wide association study of Sequenced Treatment Alternatives to Relieve Depression and meta-analysis of three studies SI Shyn, J Shi, JB Kraft, JB Potash, JA Knowles, MM Weissman, ... Molecular psychiatry 16 (2), 202-215, 2011 | 338 | 2011 |
A genomewide association study of citalopram response in major depressive disorder HA Garriock, JB Kraft, SI Shyn, EJ Peters, JS Yokoyama, GD Jenkins, ... Biological psychiatry 67 (2), 133-138, 2010 | 335 | 2010 |
Frontotemporal dementia due to C9ORF72 mutations: Clinical and imaging features SJ Sha, LT Takada, KP Rankin, JS Yokoyama, NJ Rutherford, JC Fong, ... Neurology 79 (10), 1002-1011, 2012 | 219 | 2012 |
Atypical, slowly progressive behavioural variant frontotemporal dementia associated with C9ORF72 hexanucleotide expansion BK Khan, JS Yokoyama, LT Takada, JS Sharon, NJ Rutherford, JC Fong, ... Journal of Neurology, Neurosurgery & Psychiatry 83 (4), 358-364, 2012 | 218 | 2012 |
Heightened emotional contagion in mild cognitive impairment and Alzheimer’s disease is associated with temporal lobe degeneration VE Sturm, JS Yokoyama, WW Seeley, JH Kramer, BL Miller, KP Rankin Proceedings of the National Academy of Sciences 110 (24), 9944-9949, 2013 | 196 | 2013 |
Altered network connectivity in frontotemporal dementia with C9orf72 hexanucleotide repeat expansion SE Lee, AM Khazenzon, AJ Trujillo, CC Guo, JS Yokoyama, SJ Sha, ... Brain 137 (11), 3047-3060, 2014 | 160 | 2014 |
Association between genetic traits for immune-mediated diseases and Alzheimer disease JS Yokoyama, Y Wang, AJ Schork, WK Thompson, CM Karch, ... JAMA neurology 73 (6), 691-697, 2016 | 157 | 2016 |
Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies I Broce, CM Karch, N Wen, CC Fan, Y Wang, C Hong Tan, N Kouri, ... PLoS medicine 15 (1), e1002487, 2018 | 139 | 2018 |
Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer’s disease IJ Broce, CH Tan, CC Fan, I Jansen, JE Savage, A Witoelar, N Wen, ... Acta neuropathologica 137 (2), 209-226, 2019 | 138 | 2019 |
Progranulin mutations as risk factors for Alzheimer disease DC Perry, M Lehmann, JS Yokoyama, A Karydas, JJY Lee, G Coppola, ... JAMA neurology 70 (6), 774-778, 2013 | 133 | 2013 |
Genetic architecture of sporadic frontotemporal dementia and overlap with Alzheimer's and Parkinson's diseases R Ferrari, Y Wang, J Vandrovcova, S Guelfi, A Witeolar, CM Karch, ... Journal of Neurology, Neurosurgery & Psychiatry 88 (2), 152-164, 2017 | 124 | 2017 |
A second X chromosome contributes to resilience in a mouse model of Alzheimer’s disease EJ Davis, L Broestl, S Abdulai-Saiku, K Worden, LW Bonham, ... Science translational medicine 12 (558), eaaz5677, 2020 | 113 | 2020 |
p53 is a central regulator driving neurodegeneration caused by C9orf72 poly (PR) M Maor-Nof, Z Shipony, R Lopez-Gonzalez, L Nakayama, YJ Zhang, ... Cell 184 (3), 689-708. e20, 2021 | 109 | 2021 |
Increased prevalence of autoimmune disease within C9 and FTD/MND cohorts: completing the picture ZA Miller, VE Sturm, GB Camsari, A Karydas, JS Yokoyama, LT Grinberg, ... Neurology: Neuroimmunology & Neuroinflammation 3 (6), e301, 2016 | 102 | 2016 |
Shared genetic risk between corticobasal degeneration, progressive supranuclear palsy, and frontotemporal dementia JS Yokoyama, CM Karch, CC Fan, LW Bonham, N Kouri, OA Ross, ... Acta neuropathologica 133, 825-837, 2017 | 101 | 2017 |
Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in … C Pottier, Y Ren, RB Perkerson, M Baker, GD Jenkins, M van Blitterswijk, ... Acta neuropathologica 137, 879-899, 2019 | 96 | 2019 |
Variation in longevity gene KLOTHO is associated with greater cortical volumes JS Yokoyama, VE Sturm, LW Bonham, E Klein, K Arfanakis, L Yu, ... Annals of clinical and translational neurology 2 (3), 215-230, 2015 | 94 | 2015 |
Polygenic hazard score: an enrichment marker for Alzheimer’s associated amyloid and tau deposition CH Tan, CC Fan, EC Mormino, LP Sugrue, IJ Broce, CP Hess, WP Dillon, ... Acta neuropathologica 135, 85-93, 2018 | 92 | 2018 |